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Cytoskeleton and Extracellular Matrix

Total questions: 15

Worksheet time: 8mins

Name
Class
Date
1.

Which of the following filaments are found in ALL animal cells?

a)

Keratins

b)

Vimentins

c)

Nuclear Lamins

d)

Neurofilaments

2.

Which of the following make up mitotic spindle?

a)

Intermediate filaments

b)

Microtubules

c)

Nuclear Lamins

d)

Actin filaments

3.

Microtubules are

a)

rope like

b)

mesh like

c)

hollow tubes

d)

interlocking chains and ropes

4.

The end of a growing microtubule is rich in which type of tubulin?

a)

GTP bound tubulin molecules

b)

GDP bound molecules

c)

ATP bound tubulin

d)

ADP bound molecules

5.

During muscle contraction the myosin and actin filaments do not change length?

a)

True

b)

False

6.

Inside a muscle fibre, what triggers sarcomeres to contract?

a)

sudden rise in intracellular Na+

b)

Increase levels of ATP

c)

Cell polarisation

d)

A sudden rise in intracellular Ca2+

7.

When a muscle is stimulated to contract:

a)

calcium binds to troponin which moves the tropomyosin that otherwise blocks the interaction of actin and myosin.

b)

calcium binds to tropomyosin which moves the troponin that otherwise blocks the interaction of actin and myosin

c)

calcium binds to actin allowing it to associate with myosin.

d)

calcium binds to myosin allowing it to associate with actin

8.

Supportive tissues such as bone, get their strength from

a)

cells

b)

extracellular matrix

c)

cytoskeleton filaments

9.

In connective tissues the tensile strength of the tissue is provided by

a)

Proteoglycans

b)

Collagen

c)

Actin

d)

Cellulose

10.

Which protein on a fibroblast membrane attaches to the extracellular matrix outside the cell (through adapter molecules) to actin on the inside?

a)

Proteoglycan

b)

Cadherin

c)

Fibronectin

d)

Integrin

11.

Which of the following is NOT true of gap junctions?

a)

They allow inorganic ions and small water-soluble molecules to move directly between cells.

b)

They allow ATP-driven pumps to move substances from one cell to another

c)

They allow an electrical and a metabolic coupling between the cells. They may be opened or closed as needed.

12.

In the extracellular matrix of animal tissues, which of the following molecules allows the matrix to resist compression?

a)

. Integrin

b)

Collagen

c)

Fibronectin

d)

Proteoglycans

13.

Cadherin proteins:

a)

create an electrical and metabolic coupling between epithelial cells

b)

link epithelial cells together by binding to similar cadherins in adjacent epithelial cells.

c)

allow ions and small molecules to pass from one plant cell to another.

d)

anchor epithelial cells to the basal lamina.

14.

Which type of epithelial junction plays a role in an epithelial sheet’s ability to develop tension or change its shape by contraction?

a)

Desmosome

b)

Gap junction

c)

Tight junction

d)

Adherens junction

15.

Which is the toughest and most durable of the three types of cytoskeletal filaments?

a)

Intermediate filaments

b)

Microtubules

c)

Actin Filaments