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23. DNA Replication

Total questions: 52

Worksheet time: 2hrs 38mins

Name
Class
Date
1.
Which enzyme has the job of unzipping the double helix?
a)
Helicase
b)
Polymerase
c)
Ligase
d)
Primerase
2.
Which enzyme fixes the Okazaki fragments in the lagging strand?
a)
Helicase
b)
Polymerase
c)
Ligase
d)
Primerase
3.
If a strand reads:
3' A A A T T T C 5'
The matching strand would read...
a)
5' T T T A A A G 3'
b)
3' T T T A A A G 5'
c)
5' A A A T T T C 3'
d)
3' U U U A A A G 5'
4.
This picture is illustrating the ____ nature of DNA.
a)
anti-parallel
b)
deoxyribosic
c)
helical
d)
radioactive
5.
3' and 5' refer to...
a)
How effectively the helicase works
b)
What direction the nucleotides are pointing
c)
Where the RNA primer attaches
d)
Okazaki's famous experiment
6.
The enzyme that splits open the DNA creates what's called a fork - where the DNA separates into the lagging strand and the ______ strand.
a)
leading
b)
leveraging
c)
Okazaki
d)
ligase
7.
A DNA nucleotide contains all of the following, except...
a)
Deoxyribose
b)
Phosphate group
c)
Nitrogenous base
d)
Cholesterol
8.
What is the shape of DNA?
a)
Double helix
b)
Triple helix
c)
Flat, bilayer
d)
Three-pronged rigid ladder
9.
DNA replication turns one strand of DNA into two new strands of DNA. What percent of each new strand is the old strand?
a)
Half of each new DNA is the old DNA
b)
The old strand of DNA was digested, so none
c)
The new DNA is entirely made up of the old DNA
d)
About every sixth base comes from the old DNA
10.
Sometimes, DNA is called "semi-conservative." Why might this be?
a)
The old strand is "conserved" and used to make the new strands
b)
Uracil is "conserved" in that it is only used to make the new strands
c)
ATP is "conserved" via the usage of facilitated diffusion
d)
Ligase is "conserved" in that it is denatured by the process
11.

The picture below shows the steps of DNA replication beginning with step one and ending with step three.


​Because you are reusing the old, or parent, DNA strand DNA replication is said to be

a)

Semi- Conservative

b)

Semi-discontinuous

c)

Continuous

d)

Fully-Conserveative

12.

The picture below shows an enzyme unwinding and unzipping DNA.

​

​What is the name of this enzyme?

a)

DNA Helicase

b)

DNA Ligase

c)

DNA polyermase

d)

RNA Polymerase

13.

Match he nucleotide with its complementary nucleotide. (DNA to DNA).


Adenine -

a)

Thymine

b)

Guanine

c)

Cytosine

14.

Match he nucleotide with its complementary nucleotide. (DNA to DNA).


Cytosine-

a)

Thymine

b)

Guanine

c)

Adenine

15.

Which enzyme is responsible for adding the free nucleotides to the replicating DNA? ​

a)

DNA Helicase

b)

DNA Ligase

c)

DNA polyermase

d)

RNA Polymerase

16.

Which is the first step?

a)

DNA Helicase unwinds original DNA strand

b)

RNA Primase lays down RNA primer for new nucleotide bases.

c)

DNA polymerase builds new strands by bring in new nucleotide bases.

d)

Ligase knits together fragments on lagging strand

17.

Which is the second step?

a)

DNA Helicase unwinds original DNA strand

b)

RNA Primase lays down RNA primer for new nucleotide bases.

c)

DNA polymerase builds new strands by bring in new nucleotide bases.

d)

Ligase knits together fragments on lagging strand

18.

Which is the third step?

a)

DNA Helicase unwinds original DNA strand

b)

RNA Primase lays down RNA primer for new nucleotide bases.

c)

DNA polymerase builds new strands by bring in new nucleotide bases.

d)

Ligase knits together fragments on lagging strand

19.

DNA replication runs from ______' to _____' and is said to be ______________________

a)

5, 3, antiparallel

b)

3, 5, antiparallel

c)

5, 3, parallel

d)

3, 5, parallel

20.
Which sequence of DNA bases would pair with this partial strand
CAT TCA CTG
a)
ATG TGA CAG
b)
TAC ACT GTC
c)
GTA AGT GAC
d)
CAT TCA CTG
21.
Place the following in sequential order
1. Recoil
2. Straightens the double helix
3. Breaks Hydrogen bonds
4. Adds Free nucleotides
a)
1, 2, 3, 4
b)
3, 4, 2, 1
c)
3, 2, 4, 1
d)
2, 3, 4, 1
22.
Why does DNA replicate?
a)
To create another copy for the new cell
b)
To create a duplicate copy in case the original gets damaged
c)
To create a new copy to replace the damaged original
23.

DNA replication results in

a)

2 completely new DNA molecules

b)

2 DNA molecules that each contain a strand of the original

c)

1 new DNA molecule and 1 old

d)

1 new molecule of DNA

24.

Enzyme that breaks hydrogen bonds (unzips)

a)

Ligase

b)

Polymerase

c)

Primase

d)

Helicase

25.

The new DNA strand formed after DNA replication is an exact copy of its parent strand

a)

True

b)

False

26.
A scientist observes a base sequence of AGCTAGCTAGCT.  Which of the following would be the complimentary strand?
a)
TGCATGCATGCA
b)
TCGATCGATCGA
c)
TAGCTAGCTAGC
d)
TTAAGGCCTTCC
27.
If a strand reads:
3' A A A T T T C 5'
The matching strand would read...
a)
5' T T T A A A G 3'
b)
3' T T T A A A G 5'
c)
5' A A A T T T C 3'
d)
3' U U U A A A G 5'
28.

The separation of the two single strands of DNA creates a ‘Y’ shape?

a)

enzyme

b)

unzip

c)

A replication fork

29.
What do we call DNA replication since new DNA has 1 parent strand and 1 new strand?
a)
Conservative 
b)
Semiconservative 
c)
Dispersive
30.
What is the backbone of DNA made of?
a)
Nitrogen bases
b)
Amino acids
c)
Double H
d)
Sugar & Phosphate
31.
Why is it crucial that living things are able to replicate their DNA?
a)
Each cell must have its own DNA
b)
Less copies of DNA are needed when a new cell is created
c)
A cell needs multiple copies of DNA
d)
Only muscle cells need DNA 
32.
Which enzyme is responsible for adding nucleotides?
a)
Topoisomerase
b)
DNA Polymerase
c)
Ligase
d)
Primase
33.
What are the 4 nitrogen bases?
a)
adenine, thymine, cytoplasm, and guanine
b)
adenine, thymine cytosine, and guanine
c)
adenine, thymine, cytosine, and gylcerol
d)
adenine, thymine, cytosine, and glucose
34.
What is the correct complimentary strand for the following DNA?ATCGAG
a)
TACGAG
b)
ATCGAG
c)
TAGCTG
d)
TAGCTC
35.
Which of the following best describes a DNA molecule?
a)
double helix
b)
contains ribose
c)
made of amino acids
d)
contains Uracil
36.
Which sequence of DNA bases would pair with this partial strand
ATG TGA CAG
a)
ATG TGA CAG
b)
TAC ACT GTC
c)
GTA AGT GAC
d)
CAT TCA CTG
37.
What determines the code, or information, of a DNA molecule?
a)
the shape (structure) of the nitrogen bases
b)
the order (sequence) of the nitrogen bases
c)
the color of the nitrogen bases
d)
the frequency (number) of nitrogen bases
38.

Which two molecules form the sides (backbone) of the DNA ladder?

a)

deoxyribose sugar and adenine

b)

deoxyribose sugar and a hydrogen bond

c)

deoxyribose sugar and the nucleus

d)

deoxyribose sugar and phosphate

39.
Replicate the following strand of DNA: 
AATCATGGA
a)
AATCATGGA
b)
TTAGTACCT
c)
UUAGUACCU
d)
GGATAUCUA
40.
Sometimes, DNA is called "semi-conservative." Why might this be?
a)
The old strand is "conserved" and used to make the new strands
b)
Uracil is "conserved" in that it is only used to make the new strands
c)
ATP is "conserved" via the usage of facilitated diffusion
d)
Ligase is "conserved" in that it is denatured by the process
41.
Rosalind Franklin's "Photo 51" allowed Watson and Crick to determine the _______ of DNA.
a)
Shape
b)
Backbone
c)
Nitrogen bases
d)
Hydrogen bonds
42.
Which sequence of complementary DNA bases would pair with this partial strand
ATG TGA CAG?
a)
ATG TGA CAG
b)
TAC ACT GTC
c)
GTA AGT GAC
d)
CAT TCA CTG
43.
Which of the following is the correct order of molecules?
a)
DNA -> RNA -> Proteins
b)
Proteins -> DNA -> RNA
c)
RNA -> DNA -> Proteins
d)
There is no specific order of these molecules
44.
Which of the following is the sugar found in RNA?
a)
Ribose
b)
Maltose
c)
Deoxyribose
d)
Amylose
45.
Which of the following is a correct difference between RNA and DNA?
a)
RNA is single stranded and DNA is double stranded
b)
RNA is double stranded and DNA is single stranded
c)
DNA uses Uracil and RNA uses Thymine
d)
RNA has deoxyribose and DNA has ribose
46.
The monomer of DNA is called a(n)
a)
Monosaccharide
b)
Amino Acid
c)
Triglyceride
d)
Nucleotide
47.
Which of the following is not a nitrogen base in DNA?
a)
Adenine
b)
Cytosine
c)
Uracil
d)
Thymine
48.
Which two processes are involved in protein synthesis?
a)
Replication and Transcription
b)
Replication and Translation
c)
Transcription and Translation
49.
The process of making mRNA from DNA is called.
a)
Replication
b)
Transcription
c)
Translation
d)
Protein synthesis
50.
What is the transcribed mRNA strand for CATTAA
a)
GUAAUU
b)
GTAATT
c)
AUGGUU
d)
CATTAA
51.
Choose the nucleotide sequence of the RNA strand that would be complementary to the following strand: 
GTAGTCA
a)
UATUAGA
b)
ACGACTG
c)
CAUCAGU
d)
CATCAGT
52.
Which is the mRNA molecule that would be transcribed from this DNA template:
TGGCAAGTACGT
a)
ACCGTTCATGCA
b)
UGGCAAGUACGU
c)
UCCGUUCUUGCU
d)
ACCGUUCAUGCA

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