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IB HL - Enzymes & Metabolism Intro

Total questions: 15

Worksheet time: 8mins

Name
Class
Date
1.

Which of the following describes the active site?

a)

the part of an enzyme that binds only to the product molecules

b)

the sequence of amino acids responsible for the catalytic activity of enzymes

c)

the sequence of amino acids responsible for the structure of an enzyme

d)

the specific area responsible for the activity of all proteins

2.

What determines the specificity of an enzyme for its substrate?

a)

the temperature at which is it operating

b)

the optimum pH of the enzymes

c)

the concentration of the substrate

d)

the structure of the enzyme molecule

3.

Which levels of protein structure can determine the specificity of an enzyme?

a)

primary

secondary

tertiary

b)

primary

secondary

tertiary

quaternary

c)

tertiary

quaternary

d)

primary

secondary

quaternary

4.

Which of the following determines the specificity of an enzyme?

1 - the bonding between the R groups of the polypeptide

2 - the optimum pH of the enzyme

3 - the peptide bonds between animo acids of the polypeptide

4 - the shape of the substrate molecule

a)

1, 2, 3 and 4

b)

1 and 3 only

c)

1 only

d)

2, 3 and 4 only

5.

According to the induced fit model of enzyme function,

which of the following statements is correct?

a)

active sites on enzymes are specific to a single substrate

b)

the shape of the active site can be changed by the binding of an allosteric inhibitor

c)

the binding of the substrate changes the shape of the active site slightly

d)

competitive inhibitors can change the shape of enzymes

6.

Which of the following statements are correct for the induced fit hypothesis?


1 - folding of an enzyme molecule causes the formation of the active site


2 - the shape of the active site changes to enable the substrate to bind


3 - temporary bonds hold the substrate in the active site


4 - more ES complexes are formed at the optimum temperature

a)

1 and 2

b)

1 and 3

c)

2, 3 and 4

d)

2 and 4

7.

Which of the following statements is true about enzymes?

a)

they lower the energy of activation for a reaction

b)

allosteric inhibitors bind to the active site

c)

they are used up in the reactions they catalyse

d)

they supply the energy of activation for a reaction

8.

Which statement is true of all enzymes?

a)

they are denatured at temperatures above 60°C

b)

they are inactivated at low pH values

c)

they catalyse the breakdown of large molecules into smaller ones

d)

they reduce the amount of energy required to start a reaction

9.

The graph shows the activation energy of an enzyme catalysed reaction and the same reaction without a catalyst.


Which arrow shows the activation energy of the uncatalysed reaction?

a)

A

b)

B

c)

C

d)

D

10.

The diagram shows the energy changes in a chemical reaction. What would happen to the changes in energy if this reaction was controlled by an enzyme?

a)

I would increase

b)

II would decrease

c)

I and IV would decrease

d)

II and III would decrease

11.

The graph shows the effect of an enzyme on a reaction. Which labels are correct?

a)

X is the reaction without the enzyme, W is the activation energy.

b)

X is the reaction with the enzyme, Z is the overall energy change.

c)

Y is the reaction with the enzyme, W is the difference in activation energy.

d)

Z is the energy gained by the product, W is the activation energy with the enzyme.

12.

Which reaction is an example of catabolism?

a)

Photolysis of water

b)

Denaturation of a protein by a change in pH

c)

Production of maltose from amylose by amylase

d)

Condensation of glucose to form starch

13.

Which type of chemical reaction is an example of anabolism?

a)

Combustion

b)

Condensation

c)

Hydrolysis

d)

Photolysis

14.

In which processes are macromolecules broken down into monomers?

a)

Anabolism and catabolism

b)

Catabolism and hydrolysis

c)

Hydrolysis and reduction

d)

Reduction and anabolism

15.

The equation shows a reversible reaction. In this reaction, on which molecule does an active site occur and what types of reaction occur at 1 and 2?

a)

active site on sucrase

1 = hydrolysis

2 = condensation

b)

active site on sucrase

1 = condensation

2 = hydrolysis

c)

active site on sucrose

1 = hydrolysis

2 = condensation

d)

active site on sucrose

1 = condensation

2 = hydrolysis