WorksheetsCancer 2
Total questions: 16
Worksheet time: 13mins
________________is a critical point where stop and go signals can regulate the cycle
Metastasis
Checkpoint
Malignant
Benign
Which of the following are checkpoints that the cell must pass before dividing?
Have enough nutrients
Be large enough to divide
Have correctly copied all DNA
All of the above
What is the role of protein kinases?
remove phosphate groups to deactivate enzymes
trigger apoptosis
add phosphate groups and energy to activate enzymes
stop the cell cycle
Which of these may be assessed by various proteins during a "checkpoint"? CHECK ALL THAT APPLY
Ensure that all chromosomes have lined up in the center of the cell before sister chromatids separate
Ensure that spindle fibers have attached to all centromeres before cell division
Ensure that DNA has been replicated properly
Which of the following correctly describes cells that are in the G0 phase?
Mature nerve and muscle cells are unable to divide and are permanently in G0.
Many cells enter G0 when they reach the checkpoint during the M phase.
Cells in G0 are growing and preparing for cell division.
DNA replication occurs during G0.
Which region represents the G2 phase?
Oncogenes
are mutated forms of tumor suppressor genes
are mutated forms of genes that code for proteins that normally assist in apoptosis
are mutated genes the inhibit the cell cycle
are mutated genes that code for proteins which activate cell division too often or at the improper time
Which of the following ensure that your cells will divide properly and maintain tissue homeostasis? CHECK ALL THAT APPLY!
proto-oncogenes & tumor suppressor genes
DNA repair system
apoptosis
mutations
