WorksheetsGlucose and Glycogen Metabolism (NUR-1F)
Total questions: 15
Worksheet time: 11mins
Which of the following is true about oxaloacetate?
It is an intermediary in the synthesis of glucose from glycerol
It can cross mitochondrial membranes
It is an intermediary in glycolysis
It is an intermediary in the synthesis of glucose from lactate
Which enzyme catalyzes the conversion of pyruvate to oxaloacetate?
Pyruvate Carboxylase
Pyruvate Dehydrogenase
Pyruvate Kinase
Pyruvate Phosphatase
Which glycolytic reaction cannot be directly reversed in gluconeogenesis?
Glucose-6-Phosphate → Fructose-6-Phosphate
Fructose-1,6-Bisphosphate → Glyceraldehyde-3-Phosphate
Fructose-6-Phosphate → Fructose-1,6-Bisphosphate
3-Phospho-Glycerate → 2-Phospho-Glycerate
Which of the following enzymes does NOT participate in gluconeogenesis?
Glucose-6-Phosphatase
Pyruvate Kinase
Pyruvate Carboxylase
Fructose-1,6-Bisphosphatase
Gluconeogensis in __________ provides a source of ___________ for transport in the bloodstream and use by ___________.
Muscle; glucose-6-phosphate; liver
Liver; ATP; brain
Liver; glucose-6-phosphate; brain
Liver; glucose; brain and muscle
Hexokinase is an isoenzyme of glucokinase that adds a Phosphate to Glucose upon entry to the cell. Which of the following organ expresses hexokinase?
Kidney
Liver
Muscle
Brain
All the following enzymes are involved in glycogen synthesis EXCEPT:
Hexokinase
Glycogen Synthetase
Phospho-gluco Mutase
Glycogen Synthase
This compound is broken into two in order to produce energy that will drive the reaction of UDP-glucose and Glycogenin. What is it called?
Diphosphate
Bisphosphate
Pyrophosphate
Phyrophosphate
Name the bond making up branches in glycogen
alpha-1,4-glycosidic bond
alpha-1,6-glycosidic bond
beta-1,4-glycosidic bond
beta-1,6-glycosidic bond
Primary storage site for glycogen is __________.
liver and heart
liver and skeletal muscle
liver and brain
brain and heart
How does glycogenolysis break down glycogen into glucose?
It cuts the glycogen in half
It brings the entire glycogen molecule to be broken into energy
It rearranges the glycogen molecule into glucose
It starts at the end of the branches and breaks glucose off one at a time
In which type of cell does glycogenolysis occur?
Myocytes
Hepatocytes
Both
Neither
Glycogenolysis is inactive when _______.
Muscles are active
Heart rate is normal
Heart rate is elevated
Muscles are at rest
Which of the following is NOT an activity of the debranching enzyme?
α-1,6-glucosidation
α-1,4-glucosidation
phosphorylation
glucose transfer
Glucose-6-Phosphate gets converted to Glucose in the ________ using the enzyme ________, which cannot be found in the ________.
smooth ER ; glucose-6-phosphatase ; liver cells
smooth ER ; glucose-6-phosphorylase ; liver cells
smooth ER ; glucose-6-phosphatase ; muscle cells
smooth ER ; glucose-6-phosphorylase ; muscle cells
