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Cytoscreener pre test 1

Total questions: 25

Worksheet time: 51mins

Name
Class
Date
1.

Select the type of cells seen in the smear

a)

Parabasal cells

b)

Metaplastic cells

c)

Endocervical cells

d)

Dysplastic cells

e)

Endometrial cells

2.

What is the most likely pathological change seen in the cells pointed by black arrow ?

a)

High grade dysplasia

b)

Low grade dysplasia

c)

Parakeratosis

d)

Degeneration

e)

Eosinophilic change

3.

What is the diagnostic category for this smear ?

a)

Low grade squamous intra epithelial lesion

b)

High grade squamous intraepithelial lesion

c)

NILM with atrophic changes

d)

NILM

e)

ASCUS low grade

4.

What is the most suitable name for the cells indicated by arrow ?

a)

Reactive endocervical cells

b)

Endometrial cells

c)

Endocervical cells with tubal metaplasia

d)

High grade dysplastic cells

e)

Atypical glandular cells

5.

What is the most likely option for the material indicated by arrow ?

a)

Contamination with cotton wool

b)

Cervical mucus

c)

Actinomycosis colonies

d)

Necrotic material

e)

Bacterial colonies

6.

What is the most likely diagnosis for the smear shown here ?

a)

NILM

Candida

b)

NILM

Leptotrix

c)

NILM

Fungal hyphae

d)

LSIL

Candida

e)

LSIL

Leptotrix

7.

What are the cells pointed by arrow ?

a)

Endocervical cells

b)

Endometrial cells

c)

Dysplastic cells

d)

Macrophages

e)

Lymphocytes

8.

Select all responses which are correct.

The smear shows

a)

Cells with viral cytopathic changes

b)

Features suggestive of HSV infection

c)

Cells with high grade squamous dysplasia

d)

Features of non specific infection

e)

Histiocytic giant cells

9.

What are the cells / organisms seen in the smear ?

Select all responses which are true.

a)

Intermediate cells

b)

Parabasal cells

c)

Neutrophils

d)

Trichomonas

e)

Candida

10.

What is the most likely diagnosis ?

a)

LSIL

b)

HSIL

c)

NILM

d)

ASCUS LG

e)

ASCUS HG

11.

Which of the following are true regarding the given smear ?

Select all responses which are true.

a)

Viral cytopathic changes

b)

Koilocytic aypia

c)

HPV infection

d)

LSIL

e)

ASCUS LG

12.

What is the most likely diagnosis ?

a)

Squamous cell carcinoma

b)

Adenocarcinoma

c)

High grade SIL

d)

Glandular cell atypia

e)

Low grade SIL

13.

The cell cluster seen in the smear is best described as

a)

Reactive endocervical cells

b)

Endometrial cells

c)

Atypical glandular cells

d)

Metaplastic cells

e)

HSIL

14.

What are the oval shaped structures seen in the smear?

a)

HSV inclusions

b)

HSIL cells

c)

Giant cells

d)

Pin worm eggs

e)

Keratinized cells

15.

This smear is unsatisfactory. What is the most likely error.?

a)

Inadequate cells

b)

Extensive air drying

c)

Contamination with blood

d)

Poor staining quality

e)

Poor fixation

16.

Select all correct responses

In a cervical cytology smear, features of a dysplastic squamous epithelial cell include,

a)

nuclear hyperchromasia

b)

orangiophilic cytoplasm

c)

cytolysis

d)

nuclear membrane irregularity

e)

chromatin clumping

17.

Select all correct responses

Cytoplasmic vacuolation of squamous/ glandular epithelial cells occurs in

a)

reactive changes due to an infection

b)

changes due to intra uterine contraceptive devices

c)

atrophic changes in post-menopausal females

d)

cytopathic changes due to Human Papilloma Virus infection

e)

malignant cells in invasive squamous cell carcinoma

18.

Select all correct responses

Regarding cervical cancer

a)

Squamous cell carcinoma is commoner than adenocarcinoma

b)

Both squamous and adenocarcinomas are caused by Human Papilloma virus

c)

Vaccination with bivalent HPV vaccine completely eliminates the risk of cervical cancer

d)

It occurs in females 30-50 years of age

e)

High risk sexual behaviour places women at increased risk

19.

Select all correct responses

Precursor lesions of cervical cancer

a)

invariably proceed to cervical cancer

b)

progression to invasive carcinoma occurs over months

c)

are caused by Human Papilloma Virus type 6 and 11

d)

are detected in cervical cancer screening

e)

are diagnosed definitely by colposcopic biopsy

20.

Select all correct responses

Following cytological/ smear changes and the associated infections are correctly paired

a)

Leptotrix - Chlamydia

b)

Giant cell formation - Herpes simplex infection

c)

Clue cells - Bacterial vaginosis

d)

Cytolysis - Candidiasis

e)

Chromatin clumping - Trichomonas vaginalis

21.

Select all correct responses

Regarding the cervix

a)

The position of the squamocolumnar junction changes during reproductive life

b)

The endocervix is lined by stratified squamous epithelium

c)

The low vaginal pH predisposes to squamous metaplasia of cervix

d)

The transformation zone is highly vulnerable to HPV induced changes

e)

Sampling of the squamocolumnar junction can be recognized when assessing a PAP smear

22.

Select all correct responses

Reactive glandular cells

a)

Show prominent nucleoli

b)

Are arranged in flat sheets

c)

Show nuclear membrane irregularity

d)

Show clumping of chromatin

e)

Show nuclear orientation in the same direction

23.

Select all correct responses

PAP smear of a patient with adenocarcinoma shows

a)

feathering

b)

the cells arranged in papillae

c)

three dimensional clusters

d)

macronucleoli

e)

tumour diathesis

24.

Select all correct responses

Regarding cervical cytology smear

a)

Presence of parakeratosis excludes malignancy

b)

Presence of polymorphs (neutrophils) indicates infection

c)

Tingible body macrophages are seen in follicular cervicitis

d)

Follicular cervicitis leads to lymphoma

e)

Polyballs with neutrophil infiltration are seen in patients with IUCD

25.

Select all correct responses

Regarding quality assurance in cervical cytology

a)

QC slide should run with each set of staining

b)

10% of negative slides of a cytoscreener should be re-screened

c)

The laboratory is not responsible for errors in sample collection

d)

All HSIL smears should be re-screened by a second pathologist

e)

HSIL smears should be correlated with histology