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post test cardiovascular pharmacology

Total questions: 10

Worksheet time: 6mins

Name
Class
Date
1.

When given orally, what is the calcium channel blocker with the most rapid onset of action?

a)

Nifedipine

b)

Verapamil

c)

Felodopine

d)

Diltiazem

2.

Significant intravenous absorption/inadvertent intravenous injection of bupivacaine can cause profound bradycardia and sinus node arrest. Which of the following best describes the mechanism of cardiac toxicity of bupivacaine?

a)

Bupivacaine binds inactivated fast sodium channels and dissociates from them

slowly

b)

Bupivacaine binds activated fast sodium channels and dissociates from them

slowly

c)

Bupivacaine binds inactivated slow sodium channels and dissociates from them

slowly

d)

Bupivacaine binds activated slow sodium channels and dissociates from them

slowly

3.

Which of the following antianginal agents has the highest coronary vasodilating

potential?

a)

Nitrates

b)

Verapamil

c)

Dihydropyridines

d)

β-Blockers

4.

Administration of protamine to a patient who has not received heparin can

result in

a)

Anticoagulation

b)

Hypercoagulation

c)

Profound bradycardia

d)

Hypertension

5.

Hypothyroidism and hyperthyroidism could develop in patients receiving

which of the following antidysrhythmic drugs ?

a)

Amiodarone

b)

Verapamil

c)

Procainamide

d)

Lidocaine

6.

A 54- year-old patient is undergoing a three- vessel coronary artery bypass

graft (CABG) under general anesthesia. After induction, the pulmonary

capillary wedge pressure is 15 mmHg and PA pressures are 26/13 mmHg.

Suddenly, new 30-mmHg V waves appear on the monitor screen. Systemic

blood pressure is 120/70 mmHg, heart rate is 75 beats/min, and PA pressure

is 50/35 mmHg. Which of the following drugs should be administered to the patient ?

a)

Nitroglycerin

b)

Nitroprusside

c)

Esmolol

d)

Dobutamine

7.

A 22- year-old man with HOCM is undergoing an elective cholecystectomy

under general anesthesia. Immediately after induction with propofol, 2.5

mg/kg IV , the arterial blood pressure decreases from 140/82 to 70/40 mmHg.

What would be the most appropriate drug for treatment of hypotension in this

patient ?

a)

Ephedrine

b)

Epinephrine

c)

Isoproterenol

d)

Phenylephrine

8.

Allergic reactions to protamine can occur with each of the following

EXCEPT

a)

Diabetes treated with NPH insulin

b)

Diabetes treated with regular insulin

c)

Diabetes treated with PZI insulin

d)

Previous vasectomy

9.

Which of the following medications blocks angiotensin at the receptor ?

a)

Losartan

(Cozaar)

b)

Terazosin

(Hytrin)

c)

Lisinopril

(Prinivil, Zestril)

d)

Spironolactone

(Aldactone)

10.

The effects of clopidogrel (Plavix) can be rev ersed with

a)

Fresh frozen plasma

b)

Factor VIII concentrate

c)

Aprotinin

d)

None of the above