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Ceutics Final - Dosage Form 2

Total questions: 13

Worksheet time: 7mins

Name
Class
Date
1.
Formation of a complex of drugs in the GI fluid may alter the rate and extent of drug absoption
a)
true
b)
false
2.
The complexing agent may be<br />
a)
a substance normal to the GI tract
b)
a dietary component
c)
an excipient of a dosage form
3.
When a crystalline compound is entrapped in a water solvent, it is considered a
a)
Hydrate
b)
Anhydrous
4.
Conversion from an anhydrous form to a hydrate form within the solid dosage form may reduce their dissolution rate which may
a)
reduce the rate and extent of absorption
b)
increase the rate and extent of absorption
5.
An ideal drug molecule should have
a)
an optimum partition coefficient
b)
high diffusion through lipid layers
c)
stable chemical groups
d)
a decent partition coefficient
6.

In the Zero Order release equation, X = X0 - Kt, what is X

a)

the amount (mg) or % of drug remaining to be dissolved

b)

the initial amount (mg) or 100%

c)

the zero-order dissolution rate constant (mg/hr or %/hr)

d)

time (hours)

7.

In the Zero Order release equation, X = X0 - Kt, what is X0

a)

the amount (mg) or % of drug remaining to be dissolved

b)

the initial amount (mg) or 100%

c)

the zero-order dissolution rate constant (mg/hr or %/hr)

d)

time (hours)

8.

In the Zero Order release equation, X = X0 - Kt, what is K

a)

the amount (mg) or % of drug remaining to be dissolved

b)

the initial amount (mg) or 100%

c)

the zero-order dissolution rate constant (mg/hr or %/hr)

d)

time (hours)

9.

In the Zero Order release equation, X = X0 - Kt, what is t

a)

the amount (mg) or % of drug remaining to be dissolved

b)

the initial amount (mg) or 100%

c)

the zero-order dissolution rate constant (mg/hr or %/hr)

d)

time (hours)

10.

In the First Order release equation, X = X0(1 - e^(-Kt)), what is X

a)

the cumulative amount (mg) or % of drug dissolved

b)

the initial amount (mg) or 100%

c)

the first order release rate constant (hr^-1)

d)

time (hours)

11.

In the First Order release equation, X = X0(1 - e^(-Kt)), what is X0

a)

the cumulative amount (mg) or % of drug dissolved

b)

the initial amount (mg) or 100%

c)

the first order release rate constant (hr^-1)

d)

time (hours)

12.

In the First Order release equation, X = X0(1 - e^(-Kt)), what is K

a)

the cumulative amount (mg) or % of drug dissolved

b)

the initial amount (mg) or 100%

c)

the first order release rate constant (hr^-1)

d)

time (hours)

13.

In the First Order release equation, X = X0(1 - e^(-Kt)), what is t

a)

the cumulative amount (mg) or % of drug dissolved

b)

the initial amount (mg) or 100%

c)

the first order release rate constant (hr^-1)

d)

time (hours)