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WorksheetsPharmacology- Endocrine drugs
Total questions: 28
Worksheet time: 17mins
It consist of ductless glands to secrete hormones
(a)
A chemical substance synthesized from amino acids and cholesterol
(a)
Endocrine glands are are consist of: Pituitary, thyroid, parathyroid, adrenal, gonads, pancreas.
TRUE
FALSE
It is the master gland also known as HYPOPHYSIS
2 lobes:
anterior/adenohypophysis - master gland
posterior- ADH or vasopressin and oxytocin
(a)
It stimulates the release of glucocorticoids (cortisol), mineralocorticoids (aldosterone) and androgen
(a)
It acts on bone tissues and skeletal muscle.
Regulated by GH-RH, GH-IH
(a)
It secretes T4 and T3
It controls metabolic rate and activity
It affects cardiac output, oxygen consumption, CHO use, CHON synthesis and lipolysis
It affects body heat regulation and menstrual cycle
(a)
It regulates Ca in the blood.
(a)
It has 2 sections: Adrenal medulla, adrenal cortex
(a)
It has exocrine and endocrine.
Exocrine- secretes digestive enzymes into the duodenum
Endocrine- has cell clusters; alpha islet cells, beta cells
(a)
GH: Somatostatin it is not GIVEN ORALLY, but given?
SQ
IV
IM
ID
Drugs for the deficiency of GH. It promotes bone growth at epiphyseal plates of long bones.
Acts on newly forming bone
GH can increase height by foot
bromocriptine mesylate (Parlodel)
somatrem (Protropin)
ocreotide (Sandostatin)
somatropin (Humatrope)
liotyronine (Cytomel)
It is a genetic disorder with growth deficiency, deverely obese, severe respiratory impairment
(a)
Drugs for Excess in GH. Gigantism and acromegaly.
it is due to GH hypersecretion or pituitary hormone.
bromocriptine mesylate (Parlodel)
acetohexamide (Orinase)
none
ocreotide (Sandostatin)
It is a purified extract of TSH used to diagnose primary and secondary hypothyroidism
desmopressin (DDAVP)
thyrotropin (Thyropar)
vasopressin (Pitressin)
It is used in the treatment of adrenal gland insufficiency.
It suppresses inflammatory and immune response
propanalol (Inderal)
levothyroxine (Synthroid)
corticotropin (Acthar)
If deficit, it leads to Diabetes Insipidus.
(a)
Term for hypothyroidism in adults
(a)
Term for hypothyroidism in infants
(a)
It deficient in ADH (antidiuretic hormone) , what drug will you take?
desmopressin (DDAVP)
propylthiouracil (PTU)
methimazole (Tapazole)
vasopression (Pitressin)
It is the abnormally decreased secretion of thyroid hormone
hypothyroidism
hyperthyroidism
cretinism
myxedema
Choose the right manifestation for myxedema
bradycardia
sweating
elevated HR
dysrythmia
low body temp
Drug for HYPOTHYROIDISM.
it is commonly used to increase T3 and T4
Drug of choice.
Excreted in the bile and feces
liothyronine (Cytomel)
levothyroxine (Synthroid,Levothroid)
liotrix (Euthroid)
It is the abnormal increase secretion of thyroid hormone
(a)
Check the following manifestations for hyperthyroidism
heat intolerance
exopthalmos
sweating
tachycardia
it is usually given to control cardiac symptoms for hyperthyroidism.
methimazole (Tapazole)
propythiouracil
Propanalol (Inderal)
It is the drug of choice for hyperthyroidism. It blocks thyroid hormone. No effect with thyroid tissue
Propanalol (Inderal)
thiourea derivatives (Thioamides)
paracetamol for hyperthyroidism
It is used to suppress thyroid function for those who have undergone subtotal thyroidectomy.
iodide preparations
strong Iodine solution (Lugol's sol, Potassium iodide sol)
propanalol (Inderal)
meglitinide
