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WorksheetsCell-&-Bond Round 1
Total questions: 27
Worksheet time: 20mins
The correct temporal sequence for events at the neuromuscular junction is
action potential in the motor nerve;
depolarization of the muscle end plate;
uptake of Ca2+ into the presynaptic nerve terminal
uptake of Ca2+ into the presynaptic terminal;
release of acetylcholine (ACh);
depolarization of the muscle end plate
release of ACh;
action potential in the motor nerve;
action potential in the muscle
uptake of Ca2+ into the motor end plate;
action potential in the motor end plate;
action potential in the muscle
Sensory receptor potentials
are action potentials
always bring the membrane potential of a receptor cell toward threshold
always bring the membrane potential of a receptor cell away from threshold
are graded in size, depending on stimulus intensity
During exercise, total peripheral resistance (TPR) decreases because of the effect of
the sympathetic nervous system on splanchnic arterioles
the parasympathetic nervous system on skeletal muscle arterioles
local metabolites on skeletal muscle arterioles
local metabolites on cerebral arterioles
An increase in contractility is demonstrated
on a Frank–Starling diagram by
increased cardiac output for a given end-diastolic volume
increased cardiac output for a given end-systolic volume
decreased cardiac output for a given end-diastolic volume
decreased cardiac output for a given end-systolic volume
Which of the following lung volumes or capacities can be measured by spirometry?
Functional residual capacity (FRC)
Physiologic dead space
Total lung capacity (TLC)
Vital capacity (VC)
Which of the following is true during inspiration?
Intrapleural pressure is positive
The volume in the lungs is less than the functional residual capacity(FRC)
Alveolar pressure equals atmospheric pressure
Intrapleural pressure is more negative than it is during expiration
Which of the following substances has the highest renal clearance?
Para-aminohippuric acid (PAH)
Inulin
Glucose
Na+
Cholecystokinin (CCK) inhibits
gastric emptying
pancreatic HCO3– secretion
pancreatic enzyme secretion
contraction of the gallbladder
Selective destruction of the zona glomerulosa of the adrenal cortex would produce a deficiency of which hormone?
Aldosterone
Androstenedione
Cortisol
Dehydroepiandrosterone
Which of the following causes increased aldosterone secretion?
Decreased blood volume
Administration of an inhibitor of angiotensin-converting enzyme (ACE)
Hyperosmolarity
Hypokalemia
Which of the following characteristics is shared by simple and facilitated diffusion of glucose?
Occurs down an electrochemical gradient
Is saturable
Requires metabolic energy
Is inhibited by the presence of galactose
Cutting which structure causes blindness in the temporal fields of the left and right eyes?
Optic nerve
Optic chiasm
Optic tract
Geniculocalcarine tract
The greatest pressure decrease in the circulation occurs across the arterioles because
they have the greatest surface area
the velocity of blood flow through them is the highest
the velocity of blood flow through them is the lowest
they have the greatest resistance
Carboxylation of clotting factors by VItamin K is required to be biologically active.Which of the following amino acid is carboxylated?
Histidine
Histamine
Glutamate
Aspartate
Which of the following is not an enzyme of Urea Cycle?
Arginosuccinate synthetase
Ornithine transcarbamoylase
Carbamoyl Phosphate Synthetase
Glutamate Dehydrogenase
All of the following are true about Sickle disease,except
Single nucleotide change results in change of Glutamine to Valine
RFLP result from a single base change
‘Sticky patch’ is generated as a result of replacement of a nonpolar residue with a polar residue
HbS confers resistance against malaria in heterozygotes.
Which of the following groups of proteins assist in the folding of other proteins?
Proteases
Proteosomes
Templates
Chaperones
Which is true about enzyme kinetics for competitive inhibition:
Low km high affinity
High km high affinity
High Km low affinity
Low Km low affinity
Substrate level phosphorylation is by:
Pyruvate kinase
Phosphofructokinase
Hexokinase
ATP Synthase
Sequence of events in glycogenolysis:
Phosphorylase, glucan transferase, debranching,phosphorylase
Debranching, phosphorylase, transferase, phosphorylase
Transferase, phosphorylase, debranching, phosphorylase
Any of the above
Metabolites in HMP Shunt are all except:
Glycerol-3-phosphate
Sedoheptulose-7-phosphate
Glyceraldehyde-3-phosphate
Xylulose-5-phosphate
Glycosphingolipid is not made up of:
Glucose
Glycerol
Sphingosine
Fatty acids
The first step in fatty acid synthesis involves:
Acetyl CoA Carboxylase
Beta-Hydroxyl CoA Hydrogenase
Acetyl Dehydrogenase
Pyruvate kinase
Radiolabelled DNA was allowed to replicate twice in a nonradioactive environment. Which of
the following is true?
All the strands will have radioactivity
Half of the DNA will have no radioactivity
No strands will have radioactivity
Three–fourth of the DNA replicated will have radioactivity.
Correct sequence of enzymes required for DNA formation is:
DNA polymerase → protein unwinding enzyme → DNA ligase → DNA Isomerase → Polymerase I
Protein unwinding enzyme → polymerase I → DNA ligase → DNA isomerase → DNA polymerase
RNA polymerase → DNA polymerase III →DNA polymerase I → DNA ligase
RNA polymerase → DNA polymerase III → DNA ligase → exonuclease → DNA polymerase I
Shine-Dalgarno sequence in bacterial mRNA is
near:
AUG codon
UAA codon
UAG codon
UGA codon
Severe thiamine deficiency is associated with:
Decreased RBC transketolase activity
Increased clotting time
Decreased RBC transaminase activity
Increased xanthurenic acid excretion
