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WorksheetsNSCLC
Total questions: 15
Worksheet time: 15mins
What is lung cancer?
Starts when lung cell become abnormal.
Grow out of control.
Only local invasive and never spread.
80-85% are Non small cell lung cancer.
The following are the etiologies of Non small cell lung cancer?
Active smoking.
Non smokers.
Genetic Susceptibility.
Radon.
Which of the following shows the growth of NSCLC?
Involved in the protection of the airways.
Arise from epithelial cells of the lung of the central bronchi to terminal alveoli.
Invasive and rapidly growing cancer.
Involve genes of BRCA 1 and 2
Below is the type of histological subtype of NSCLC?
Squamous cell lung carcinoma
Lung large cell carcinoma
Lung adenocarcinoma
Small cell lung cancer.
Non small cell lung cancer normally occurs at
Distal
Central
Proximal
Peripheral
The genetic pathogenesis of NSCLC is due to
Amplification
Activation
Inactivation
Invasive
Risk factors of NSCLC?
History of tobacco usage
Exposure among secondhand smoke
Occupational exposure
Beta carotene supplements in heavy smokers.
Adenocarcinoma
Others name is bronchoalveolar carcinoma
TTF -1 is positive
CK 7 negative
CK 20 negative
Squamous cell carcinoma consist of cells that produce a keratin, normally the histochemically tend to
TTF-1 negative
Positive in CK 5 & 6
Negative in P63
Positive in P40
The followings tumour markers are commonly use in NSCLC?
CEA
ALK
EGFR
BRCA
Diagnostic and staging for NSCLC?
Physical examination.
Chest X ray
Biopsy
Tumour marker
The reason of administering a skin test - intradermal injection lignocaine 2 % (0.1 ml) 1 day before procedure?
Sedation purpose.
Reduce an allergic reaction.
Reduce a bronchospasm.
As anesthetic agent.
Pre medication commonly given for Bronchoscopy procedure?
IM Pethidine
IM Ranitidine
IM Atropine
Nitroderm patch
The followings drugs are common used to treat NSCLC?
Carboplatin
Cisplatin
Irinotecan
Gemcitabine
Which are following EGFR may effective to stop or slowing the growth of lung cancer?
Erlotinib
Gefitinib
Avastin
Cetuximab
