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Osteoporosis Drug Quiz

Total questions: 23

Worksheet time: 20mins

Name
Class
Date
1.

Which of these T-scores can be considered Osteoporosis?

a)

-3

b)

-2.5

c)

-2

d)

-1.5

e)

-3.5

2.

Which of these are antiresorptive agents for osteoporosis?

a)

Estrogen

b)

Calcitonin

c)

Bisphosphonates

d)

Teriparatide

e)

Romosozumab

3.

Anabolic agents used as therapies for osteoporosis include romosozumab, abaloparatide, and (a)   .

4.

Central DXA measures bone density at what 2 locations?

(a)  

5.

You want to evaluate your patient's fracture risk. What assessment tool can you use?

(a)  

6.

Based on the NOF guidelines, you should consider pharmacologic therapy if your patient has had which of the following?

a)

hip fracture

b)

T-score = -1.8 at the femoral neck

c)

low bone mass and 10-year probability of hip fracture = 2% based on FRAX

d)

T-score = -2.6 in the lumbar spine

e)

low bone mass and 10-year probability of major osteoporosis-related fracture = 15%

7.

Which of these stimulate bone formation?

a)

PTH analogs

b)

Sclerostin inhibitors

c)

Estrogen

d)

SERMs

e)

Bisphosphonates

8.

Bisphosphonates are antiresorptive agents that include zoledronic acid, risedronate, ibandronate, and (a)   .

9.

Denosumab can be used as osteoporosis therapy for which of the following?

a)

postmenopausal osteoporosis prevention

b)

postmenopausal osteoporosis treatment

c)

glucocorticoid-induced osteoporosis prevention

d)

glucocorticoid-induced osteoporosis treatment

10.

Which of these medications are indicated to use as postmenopausal osteoporosis prevention?

a)

calcitonin

b)

raloxifene

c)

ibandronate

d)

alendronate

e)

zoledronic acid

11.

Calcitonin has been shown to be effective in reducing which of the following?

a)

vertebral fracture

b)

nonvertebral fracture

c)

hip fracture

12.

Risedronate has been shown to be effective in reducing which of the following?

a)

vertebral fracture

b)

nonvertebral fracture

c)

hip fracture

13.

Raloxifene has been shown to be effective in reducing which of the following?

a)

vertebral fracture

b)

nonvertebral fracture

c)

hip fracture

14.

Which of these are safety risks with bisphosphonates?

a)

breast cancer

b)

VTE

c)

osteonecrosis of the jaw

d)

esophageal irritation

e)

UTI

15.

What's shown here?

(a)  

16.

Which are risk factors for ONJ?

a)

bisphosphonate exposure

b)

raloxifene exposure

c)

cancer

d)

corticosteroid use

17.

Denosumab is a fully human monoclonal antibody to what osteoclast differentiating factor?

(a)  

18.

Which of these are 1st line osteoporosis treatments?

a)

bisphosphonates

b)

denosumab

c)

raloxifene

d)

calcitonin

19.

Teriparatide has been shown to be effective in reducing which of the following?

a)

vertebral fracture

b)

nonvertebral fracture

c)

hip fracture

20.

Which drug can potentially cause osteosarcomas?

a)

teriparatide

b)

raloxifene

c)

bisphosphonates

d)

calcitonin

21.

Which drug is an antibody to sclerostin, an osteocyte-secreted glycoprotein regulator of bone formation?

a)

romosozumab

b)

abaloparatide

c)

teriparatide

d)

denosumab

22.

This can occur as an adverse effect of which drug(s)?

a)

estrogen

b)

calcitonin

c)

raloxifene

d)

bisphosphonates

e)

denosumab

23.

You've decided to prescribe Alendronate to your patient with osteoporosis. What dosing would you recommend?

a)

5 mg daily

b)

2.5 mg daily

c)

210 mg once a month

d)

60 mg daily