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Bone Formation and Remodeling Quiz

Total questions: 22

Worksheet time: 18mins

Name
Class
Date
1.

What type of bone can be found at this blue arrow?

(a)  

2.

What's this pink layer called at the blue arrow?

(a)  

3.

Which of the following is derived from the fusion of multiple hematopoietic stem cells?

a)

A

b)

B

c)

C

d)

D

4.

Which of the following are formed from osteoblasts?

a)

A

b)

B

c)

C

d)

D

5.

What kinds of cells are in the area labeled B?

(a)  

6.

Which of these are irregular bones?

a)

tibia

b)

humerus

c)

metacarpals

d)

tarsals

e)

vertebrae

7.

Which of these are short bones?

a)

tibia

b)

carpals

c)

metacarpals

d)

tarsals

e)

vertebrae

8.

Osteoblasts are derived from undifferentiated mesenchymal cells or (a)   .

9.

Osteoblasts are formed from osteoprogenitor and mesenchymal cells in what location(s)?

a)

periosteum

b)

endosteum

c)

compact bone

d)

yellow bone marrow

10.

What do you call the organic matrix of bone that osteoblasts secrete?

(a)  

11.

Which of these are characteristics of osteoid?

a)

60-70% type I collagen

b)

includes proteoglycans

c)

>80% type II collagen

d)

forms calcium oxalate crystals

e)

>90% type I collagen

12.

Osteoid mineralizes following increase of calcium and...

(a)  

13.

How long does mineralization of osteoid in humans take?

a)

2-3 days

b)

2-3 weeks

c)

1-2 months

d)

1-2 years

14.

What allows osteocytes to contact each other?

a)

blood vessels

b)

canaliculi

c)

lacunae

d)

osteoblasts

e)

proteoglycans

15.

Which of these are potential "fates" of osteoblasts?

a)

osteocytes

b)

osteoclasts

c)

apoptosis

d)

bone-lining cells

e)

osteoprogenitor cells

16.

Osteoclasts are often located in what spaces? (be specific)

(a)  

17.

Which of these do osteoclasts release?

a)

H+

b)

CO2

c)

lysosomal enzymes

d)

type I collagen

e)

proteoglycan

18.

What is the primary signal for pre-osteoclasts cells to differentiate into osteoclasts?

(a)  

19.

Which of the following are true about osteoclast differentiation?

a)

PTH binds to osteoclast PTH receptors

b)

PTH binds to osteoblast PTH receptors

c)

osteoclasts release RANKL

d)

osteoblasts release M-CSF

e)

binding to RANK receptors on pre-osteoclasts

20.

Osteoprotegerin production by osteoblasts is stimulated by what hormone?

(a)  

21.

What does osteoprotegerin do?

a)

stimulates bone resorption

b)

binds to RANKL

c)

binds to RANK

d)

inhibits bone formation

22.

What law refers to the capacity for functional adaptation of bone - responding to external strain through modification of form?

(a)