Oxygen independent killing mechanism requires phagosome-lysosome fusion.

Hydrogen peroxide (H₂O₂) is one the microbicidal compounds involved in the intracellular pathogen killing mechanisms.

Classical dendritic cells respond to IFN-γ produced by adaptive immune cells.

B cells are the antigen presenting cells for the T-dependent antigens.

The Major Histocompatibility Complex (MHC) is located on the long arm of chromosome 6.

HLA-DP, HLA-DQ and HLA-DR are the HLA class 1 molecules.

The β2 microglobulin chain is part of class II HLA molecule.

Non-consanguineous marriage in a human population may contribute to their survival from a novel infectious disease outbreak.

Antigen processing for presentation by MHC class II molecules involves HLA-DM.

HLA class I is stabilized by chaperones in the endosomal vesicles.

Restricted HLA class II antigens are recognized by the CD4+ T cells.

Expression of RAG genes is required for the maturation process of both T and B cells.

High-affinity antibodies are produced by B cells activated by lipid antigens.

Signals from complement proteins enhance the activation of B cells by polysaccharide antigens.

Increase in total IgE is seen in patients with parasitic infections.

Follicular dendritic cells display native antigens to memory B cells during affinity maturation.

During negative selection, thymocytes that can recognise self-antigens on self MHCs with high avidity are allowed to survive.

Signals from co-stimulatory molecules cause the differentiation of naïve T cells into effector T cells.

Expression of FAS ligand (FasL) on activated cytotoxic T lymphocytes causes the lysis of target cells expressing Fas.