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Phamacology 1

Total questions: 10

Worksheet time: 7mins

Name
Class
Date
1.

What functional group is acidic?

a)

alcohol

b)

guanidines

c)

ketones

d)

sulfonamides

2.

What drug has a quaternary ammonium and cannot cross the BBB?

a)

neostigmine

b)

clopidogrel

c)

polytoin

d)

warfarin

3.

What pH are unionized acidic and basic drugs absorbed in?

a)

HA- high pH

B- low pH

b)

HA- low pH

B- high pH

c)

A-: high pH

BH+: low PH

d)

A-: low pH

BH+: high pH

4.

Endocytosis is a form of?

a)

active transport

b)

simple diffusion

c)

facilitated simple diffusion

d)

ion channel

5.

What drug is acid labile?

a)

excedrin

b)

phenegran

c)

aspirin

d)

insulin

6.

If a P.C > 1 ; the drug is?

a)

hydrophobic

b)

hydrophilic

c)

lipophilic

d)

amphipathic

7.

what is the strongest bond strength to weakest?

a)

ionic, covalent, hydrophobic, hydrogen, van der waals

b)

covalent, ionic, hydrogen, hydrophobic, van der waals

c)

covalent, ionic, hydrophobic, hydrogen, van der waals

d)

covalent, hydrogen, ionic, hydrophobic, van der waals

8.

which drugs bind to the protein albumin? 3 of 5

a)

barbiturates

b)

benzodiazepines

c)

propranalol

d)

methadone

e)

NSAID

9.

microsomal enzymes are located where? non-microsomal?

(a)  

10.

GFR molecular weight max? binary excretion min?

(a)