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Worksheets

Honors Genetics

Total questions: 48

Worksheet time: 28mins

Name
Class
Date
1.

Which of the following describes the difference between a purine and a pyrimidine?

a)

Purines are single ring structures and include C and A while pyrimidines are double ring structures and include T and G

b)

Pyrimidines are single ring structures and include C and A while purines are double ring structures and include T and G.

c)

Purines are single ring structures and include T and C while pyrimidines are double ring structures and include A and G

d)

Pyrimidines are single ring structures and include T and C while purines are double ring structures and include A and G.

2.

What is the correct sequence of protein synthesis?

A. tRNA brings amino acids to the ribosome

B. DNA molecules serve as the templates for mRNA.

C. mRNA molecules move to ribosomes.

D. Polypeptides are formed on ribosomes.

a)

A-B-C-D

b)

B-C-A-D

c)

C-B-A-D

d)

D-B-A-C

3.

This is what DNA stands for

a)

dinucleotideadenosine

b)

doublenucleotide acid

c)

dinucleotide acid

d)

deoxyribonucleic acid

4.

What are the building blocks (monomers) that compose DNA and RNA?

a)

amino acids

b)

nucleic acids

c)

nucleotides

d)

proteins

5.

A relatively weak bond that forms between the two nitrogen bases holding the two sides of the DNA molecule together.

a)

hydrogen bond

b)

covalent bond

c)

peptide bond

d)

ionic bond

6.

Deoxyribose is

a)

the nucleotide of DNA

b)

the sugar found in DNA

c)

the sugar found in RNA

d)

none of the above

7.

Name the three components of the nucleotides that compose DNA.

a)

sugar, nitrogen base, protein

b)

sugar, phosphate, hydrogen bond

c)

phosphate, nitrogen base, hydrogen bond

d)

sugar, nitrogen base, phosphate

8.

What are Chargaff's (complementary) base pairing rules for DNA?

a)

A--T

C--G

b)

C--G

A--U

c)

C--A

G--T

d)

C--T

G--A

9.

1.Which nitrogen base is found in RNA, but not found in DNA?

a)

thymine

b)

uracil

c)

adenine

d)

guanine

10.

Why is transcription necessary?

a)

DNA has to directly be used to make a protein, so we have to turn it into amino acids

b)

DNA can't leave the nucleus, and ribosomes, which make proteins, aren't in the nucleus.

c)

RNA can't leave the nucleus so DNA has to be converted to make a protein.

d)

none of the above

11.

What makes up the “sides” or backbone of the DNA ladder?

a)

nitrogen bases

b)

alternating sugars and phosphates

c)

sugars and bases

d)

phosphates and bases

12.

What purpose does DNA serve in a cell?

a)

short-term energy storage

b)

long-term energy storage

c)

stores instructions for making proteins and hereditary information

d)

none of the above

13.

Which molecule is this?

a)

protein

b)

carbohydrate

c)

nucleotide

d)

lipid

14.

Name the 3 parts of the molecule

a)

1. sugar

2. phosphate

3. nitrogen base

b)

1. phosphate

2. nitrogen base

3. sugar

c)

1. phosphate

2. sugar

3. nitrogen base

d)

1. nitrogen base

2. phosphate

3. sugar

15.

What about DNA, specifically, determines the traits of an organism and what protein is made?

a)

the order of the bases

b)

how many bases

c)

which cell the DNA is in

d)

none of the above

16.

DNA is ___stranded; RNA is ____ stranded

a)

single;single

b)

double; single

c)

double; double

d)

single; double

17.

What is this molecule?

a)

mRNA

b)

RNA

c)

tRNA

d)

rRNA

18.

In order for genes to be expressed (“made” so to speak), what two processes must occur?

a)

first translation, then transcription

b)

first DNA replication, then transcription

c)

first DNA replication, then transcription, then translation

d)

first transcription then translation

19.

This protein adds complementary RNA bases to a strand of DNA during transcription

a)

DNA polymerase

b)

Helicase

c)

RNA polymerase

d)

none of the above

20.

What is the function of tRNA?

a)

carries information from DNA to the ribosome

b)

reads the mRNA

c)

turns DNA into mRNA

d)

brings amino acids to the ribosome

21.

The purpose of mRNA is to carry the protein building instructions from __1__ in the ___2_ to the __3__ located in the ___4____

a)

1.RNA

2.DNA

3. Ribosome

4. cytoplasm

b)

1. DNA

2. RNA

3. Ribosome

4. Cytoplasm

c)

1. DNA

2. Nucleus

3. Ribosome

4. Cytoplasm

d)

1. Ribosome

2. Cytoplasm

3. DNA

4. Nucleus

22.

Where does transcription occur?

a)

cytoplasm

b)

rough ER

c)

nucleus

d)

A and B

23.

Transcribe and translate the following DNA strand:

TTCTACTGGCCCACT

a)

AAGAUGACCGGGUGA

MET-THR-GLY-Stop

b)

AAGAUGACCGGGUGA

c)

AAGATGACCGGGTGA

MET-THR-GLY-Stop

d)

AAGATGACCGGGTGA

LYS-MET-GLY-stop

24.

What happens to the DNA strand after transcription is completed?

a)

its is destroyed

b)

it is replicated

c)

nothing

d)

it zips back up

25.

The start codon is

a)

MET

b)

AUG

c)

UAC

d)

none of the above

26.

What is transcription?

a)

turning mRNA into a protein

b)

Replicating DNA

c)

turning DNA into mRNA

d)

turning mRNA into tRNA

27.

What is the central dogma? Choose all that apply

a)
b)
c)

DNA is transcribed into mRNA which is translated into a polypeptide.

d)

DNA is replicated. The replicated DNA is transcribed into mRNA and the mRNA is translated into a protein.

28.

What does #1 represent?

a)

DNA

b)

tRNA

c)

protein

d)

mRNA

29.

The monomer of proteins

a)

polypeptide

b)

nucleotide

c)

peptide

d)

amino acid

30.

A codon is

a)

a sequence of 3 bases found on mRNA

b)

a sequence of 3 bases found on tRNA

c)

a sequence of 3 bases found on DNA

d)

3 nucleotides on tRNA and mRNA

31.

how many codons code for 1 amino acid?

a)

1

b)

2

c)

3

d)

4

32.

A gene is (choose all that apply)

a)

a section of DNA that gives instructions for making a protein

b)

found on chromosomes

c)

made up of chromosomes

d)

made up of nucleotides

33.

What type of bonds connect amino acids?

a)

covalent

b)

peptide

c)

ionic

d)

hydrogen

34.

What does #4 represent?

a)

codons

b)

amino acid

c)

anticodon

d)

mRNA

35.

This section of mRNA is edited out

a)

intron

b)

exon

c)

TATA box

d)

poly-A tail

36.

This section of mRNA is expressed

a)

intron

b)

poly-a tail

c)

exon

d)

5' cap

37.

What is the complementary strand of DNA to the one below?

5' CAGTGCTGA 3'

a)

5' GUCACGACU 3'

b)

5' GTCACGACT 3'

c)

3' GUCACGACU 5'

d)

3' GTCACGACT 5'

38.

Which enzyme unzips DNA during replication?

a)

RNA polymerase

b)

DNA polymerase

c)

Helicase

d)

Primase

39.

DNA polymerase is responsible for (CHOOSE ALL THAT APPLY)

a)

proofreading DNA strands

b)

pairing new DNA bases during transcription

c)

pairing new DNA bases during replication

d)

pairing mRNA bases for transcription

40.

Which of the following represents semi-conservative? CHOOSE ALL CORRECT

a)
b)
c)
d)

each newly synthesize DNA molecule is made of one original strand and one new strand

41.

Ligase

a)

glues okazaki fragments together on the leading strand

b)

glues okazaki fragments together on the lagging strand

c)

adds RNA primers so replication can begin

d)

proofreads the new strand

42.

Which is the first step?

a)

DNA Helicase unwinds original DNA strand

b)

RNA Primase lays down RNA primer for new nucleotide bases.

c)

DNA polymerase builds new strands by bring in new nucleotide bases.

d)

Ligase knits together fragments on lagging strand

43.

Which is the second step?

a)

DNA Helicase unwinds original DNA strand

b)

RNA Primase lays down RNA primer for new nucleotide bases.

c)

DNA polymerase builds new strands by bring in new nucleotide bases.

d)

Ligase knits together fragments on lagging strand

44.

Which is the third step?

a)

DNA Helicase unwinds original DNA strand

b)

RNA Primase lays down RNA primer for new nucleotide bases.

c)

DNA polymerase builds new strands by bring in new nucleotide bases.

d)

Ligase knits together fragments on lagging strand

45.

Which is the fourth step?

a)

DNA Helicase unwinds original DNA strand

b)

RNA Primase lays down RNA primer for new nucleotide bases.

c)

DNA polymerase builds new strands by bring in new nucleotide bases.

d)

Ligase knits together fragments on lagging strand

46.

The directionality of DNA is said to be ___________, because it is side by side by goes in opposite directions.

a)

Anti-directional

b)

Parallel

c)

Anti-parallel

d)

Anti-uniform

47.

direction new nucleotides are synthesized on the new strand

a)

5' to 3' (new nucleotides added to the 3' end)

b)

3' to 5' (new nucleotides added to the 5' end)

c)

3' to 5' (new nucleotides added to the 3' end)

d)

5' to 3' (new nucleotides added to the 5' end)

48.

Lagging strand is the :

a)

Continuous strand

b)

Parental strand

c)

New strand

d)

Discontinuous strand