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THYROID GLAND FUNCTION

Total questions: 21

Worksheet time: 12mins

Name
Class
Date
1.

Thyroid gland secretes three different hormones, but generally thyroid hormones refer to .. ?

a)

T3, T4

b)

Calcitonin

c)

T3, Calcitonin

d)

T4

2.

T3 and T4 helps to .. ?

a)

Increase cell metabolism

b)

Increase oxygen consumption

c)

Regulate body temperature

d)

Regulate blood pressure

3.

Hyposecretion of thyroid hormones cause .. ?

a)

Decreased body temperature

b)

Weight gain

c)

Elevated cholesterol level in blood

d)

High blood pressure

4.

When you are in a cold room, skin receptor sends signals and cause Hypothalamus to secrete ...... which then increase the secretion of ... by pituitary gland. This hormone circulates in bloodstream and then stimulate the release of .... and ... into blood. Body metabolism increase and produces heat to withstand the cold room.

a)

TRH, TSH, T3 & T4

b)

T4, T3, TSH & TRH

c)

TSH, TRH, T4 & T3

d)

TRH, T3, TSH & T$

5.

The synthesis of thyroid hormones requires .. ?

a)

Tyrosine

b)

Iodide

c)

Magnesium

d)

Glutamine

6.

The reaction of organification of iodide results in ... and ....

a)

MIT

b)

DIT

c)

TIT

d)

PIT

7.

DIT + DIT =

a)

T3

b)

T4

c)

T5

d)

Calcitonin

8.

DIT + MIT =

a)

T3

b)

T4

c)

T5

d)

Calcitonin

9.

T3 and T4 hormones need transport proteins in the plasma, which are .. ?

a)

Albumin

b)

Transthyretin

c)

Thyroxine-binding globulin

d)

Tyrosine

10.

Goiter can occur due to .. ?

a)

Hypothyroidism

b)

Hyperthyroidism

c)

Hyperglycemia

d)

Hypotension

11.

How does goiter in hypothyroidism occur?

a)

Nonfunctional T3&T4 cannot promote negative feedback

b)

Malfunction of thyroid gland and produce many thyroid hormone

c)

Continuous stimulation of thyroid gland

d)

Thyroid gland stimulated to secrete more T3&T4

12.

How does goiter in primary hyperthyroidism occur?

a)

Nonfunctional T3&T4 cannot promote negative feedback

b)

Malfunction of thyroid gland and produce many thyroid hormone

c)

Continuous stimulation of thyroid gland

d)

Thyroid gland stimulated to secrete more T3&T4

13.

The secondary hyperthyroidism found in goiter patient happens due to .. ?

a)

TSH & TRH become abnormal and no longer sensitive to negative feedback

b)

TSH & TRH become abnormal and no longer sensitive to positive feedback

c)

T3 & T4 become abnormal and no longer sensitive to negative feedback

d)

T3 & T4 become abnormal and no longer sensitive to positive feedback

14.

Hypothyroidism can be caused by either thyroid gland malfunction (primary) or Pituitary deficiency of TSH (secondary). How can we differentiate the two causes?

a)

TSH measurement

b)

TRH measurement

c)

FT4 measurement

d)

FT3 measurement

15.

Primary hypothyroidism can cause .. ?

a)

Cretinism

b)

Myxedema

c)

Hashimoto's thyroiditis

d)

Graves disease

16.

An abnormal level of TSH with normal level of FT4 can be a sign of .. ?

a)

Subclinical hyperthyroidism

b)

Primary hypothyroidism

c)

Secondary hypothyroidism

d)

Hyperthyroidism

17.

Aside for Thyroid Function Test, we can also perform Radioactive Iodine Uptake (RAIU) as diagnostic test. Low uptake of radioactive iodine means .. ?

a)

Gland is metabolically inactive

b)

Gland is metabolically active

c)

Hashimoto's thyroiditis

d)

Toxic adenoma

18.

Cretinism is a disease caused by hypothyroidism due to .. ?

a)

Hypofunction/absence of gland

b)

Diminished production of thyroxine

c)

Autoimmune antibodies attack the gland

d)

Autoimmune disease that cause gland to be overactive

19.

Myxedema is a disease caused by hypothyroidism due to .. ?

a)

Hypofunction/absence of gland

b)

Diminished production of thyroxine

c)

Autoimmune antibodies attack the gland

d)

Autoimmune disease that cause gland to be overactive

20.

Hashimoto's thyroiditis is a disease caused by hypothyroidism due to .. ?

a)

Hypofunction/absence of gland

b)

Diminished production of thyroxine

c)

Autoimmune antibodies attack the gland

d)

Autoimmune disease that cause gland to be overactive

21.

Graves disease is a disease caused by hyperthyroidism due to .. ?

a)

Hypofunction/absence of gland

b)

Diminished production of thyroxine

c)

Autoimmune antibodies attack the gland

d)

Autoimmune disease that cause gland to be overactive