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Mutations/Genetic Engineering

Total questions: 40

Worksheet time: 29mins

Name
Class
Date
1.

DNA molecule segment is : TTACGCAAG

The mutated DNA segment is TTACGCAAC. This is an example of ___ mutation.

a)

Substitution

b)

Insertion

c)

Inversion

d)

Translocation

2.
Any change in the sequence of DNA is...
a)
transgenic shift
b)
Single Genotype
c)
Monohybrid Trait
d)
Mutation
3.

Which organelle is DNA usually found in?

a)

cell membrane

b)

vacuole

c)

chloroplast

d)

nucleus

4.

ATT-TGA-GCC- Original

ATT-GAG-CC - Mutated

The example above is an example of a

a)

Insertion- Frameshift

b)

Deletion- Substitution

c)

Deletion -Frameshift

d)

All of the above

5.

Original DNA: CAT GAT CCA

New DNA: CAT TGA TCC A

What mutation occurred?

a)

deletion

b)

substitution

c)

tranverse

d)

insertion

6.
Original: ATC CAT
Mutation: ATC GCAT
What mutation occurred?
a)
deletion
b)
insertion
c)
silent
d)
transverse
7.
Mutated DNA sequences that can be passed from parent to offspring --
a)
occur in somatic cells (body cells)
b)
occur in gametic cells (sex cells)
c)
are rejected by meiosis
d)
only occur if the parent is exposed to harmful substances
8.
a)
This karyotype shows Trisomy 21
b)
This karyotype has no abnormality
c)
This karyotype is missing a sex chromosome (monosomy x)
d)
This karyotype is from a gamete
9.
Based on the Karyotype shown, at which chromosome pair can we identify a genetic disorder? 
a)
Chromosome pair 5
b)
sex chromosomes
c)
Chromosome pair 21
d)
There are no chromosomal disorders
10.
What is the chromosomal condition of the individual whose karyotype is seen in the image?
a)
Monosomy X (Turner's Syndrome)
b)
Trisomy 21 (Down's Syndrome)
c)
Trisomy 13 (Patau Syndrome)
d)
Trisomy 18 (Edwards's Syndrome)
11.
Nondisjunction can result in 
a)
trisomy conditions
b)
monosomy conditions
c)
additional sex chromosomes
d)
all of these
12.
When chromosomes fail to separate correctly during anaphase of meiosis, what can occur?
a)
extra chromosomes are found in the sex cell
b)
chromosomes of the sex cell are doubled
c)
chromosomes of the sex cell are halved
d)
meiosis never completes
13.
Down's syndrome occurs because of a(n)
a)
missing sex chromosome
b)
extra sex chromosome
c)
additional 21st chromosome
d)
additional 18th chromosome
14.

What would you call the failure of one or more pairs of homologous chromosomes or sister chromatids to separate normally during meiosis?

a)

nondisjunction

b)

anaphase I

c)

nondiploidy

d)

karyotype

15.
Determine the sex of the individual whose karyotype is displayed in the image.
a)
female
b)
male
16.
What makes this individual's karyotype not normal?
a)
An extra sex chromosome
b)
An extra autosome
c)
A missing sex chromosome
d)
A missing autosome
17.

Turner's Syndrome, as shown in this karyotype, has a karyotype notation of

a)

47XX+21

b)

47XXY

c)

45XO

d)

44XX

18.

Klinefelter's Syndrome as shown in this karyotype has a notation of

a)

47XX+21

b)

47XXY

c)

45XO

d)

44XX

19.
Which would be considered a somatic cell?
a)
Sperm cell
b)
Egg Cell
c)
Skin Cell
d)
All of these
20.
If the Diploid number of Carrots is 18, the haploid number is
a)
18
b)
9
c)
27
d)
36
21.

The cells produced by meiosis are called:

a)

sex cells/gametes

b)

somatic cells

c)

body cells

d)

skin cells

22.

What is recombinant DNA

a)

DNA from 2 different organisms combined

b)

DNA from 2 different ribosomes

c)

DNA that is separated out from a vector

23.
When DNA is manipulated and moved from one source to another it is known as
a)
genetic engineering
b)
electrophoresis
c)
gene therapy
d)
GMO
24.
Which term refers to a farmer choosing the best corn from this year to plant next year?
a)
natural selection
b)
selective breeding
c)
genetic engineering
d)
genetic transformation
25.
Someone has a wild cat breed with a house cat in order to have a cat that looks wild but is more gentle. This is__.
a)
Genetic Modification
b)
Gene Therapy
c)
Animal Husbandry
d)
Selective breeding
26.
Choosing which organisms can have offspring is_____.
a)
Selective Breeding
b)
Gene Modification
c)
Gene Therapy
d)
Animal Husbandry
27.

What is a GMO?

a)

An organism that has had its DNA modified by humans

b)

An organism missing a chromosome

c)

Epigenetics

d)

A genetically identical organism

28.
Putting the gene for bioluminescence into a fish is an example of...
a)
Genetic Engineering
b)
Selective Breeding
c)
Artificial Selection
d)
Gene Mutation
29.
DNA can be spliced, in order to insert it in a different organism, using
a)
prescription enzymes
b)
digestive enzymes
c)
restriction enzymes
d)
transcription enzymes
30.
When human DNA is inserted in bacterial DNA to create insulin it is called
a)
viral DNA
b)
bacterial DNA
c)
recombinant DNA
d)
transcribed DNA
31.
Which two bat species are most closely related?
a)
 Bat 1 and Bat 2
b)
Bat 1 and Bat 3
c)
Bat 2 and Bat 3
d)
There’s no way to tell
32.

A student performed a gel electrophoresis experiment. The results are represented in the diagram

below. Compared to the fragments at the top of the gel, the fragments at the lower end are

a)

larger, and move slower

b)

larger, and move faster

c)

smaller, and move faster

d)

smaller, and move slower

33.

What is the first cloned mammal?

a)

goat

b)

cat

c)

sheep

d)

cow

34.

Clones have the exact same:

a)

Personalities

b)

Physical appearances

c)

Intelligence levels

d)

Genetic material

35.

A technique for making millions of copies of a specific region of DNA.

a)

DNA ligase

b)

restriction enzymes

c)

gel electrophoresis

d)

polymerase chain reaction

36.

Which suspect should be charged with the crime?

a)

Suspect 1

b)

Suspect 2

c)

Suspect 3

d)

None of these suspects

37.

In a gel electrophoresis tank, will the DNA move towards the positive or negative electrode?

a)

Positive

b)

Negative

38.

Hair samples found at the crime scene during a murder investigation were used to obtain the genetic profile. The sample was checked against the 3 suspects. Which of the suspects committed the crime?

a)

Suspect 3.

b)

Any of them could be the killer.

c)

Suspect 1.

d)

Suspect 2.

39.
Genetic engineering has been used to produce
a)
medicines.
b)
food animals.
c)
improved crops.
d)
all of these.
40.
Based on these results whose blood was found in the blood stain at the crime scene?
a)
Bob
b)
Sue
c)
John
d)
Lisa

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