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WorksheetsSC 30244 Final Exam Feb 2022 M 5/4
Total questions: 205
Worksheet time: 3hrs 25mins
In RNA, the nitrogen base____ replaces ____ that was present in DNA.
A, U (adenine, uracil)
C, G (cytosine, guanine)
U, T (uracil, thymine)
U, A (uracil, adenine)
The "central dogma" states that genetic information flows from
Protein-->mRNA-->DNA
Protein-->DNA-->mRNA
mRNA-->DNA-->Protein
DNA-->mRNA-->Protein
Which do DNA and RNA have in common?
Both are double stranded.
Both contain ribose molecules.
Both contain phosphate groups.
Both contain uracil.
T-G-A-C-C-A
T-G-A-G-C-A
5'-AUG-UCU-UCG-UUA-UCC-UUG-3'
What must happen to a newly made polypeptide before it can be secreted from a cell?
it must be translated by a ribosome found in the cytoplasm of the cell and then sent toward the cell membrane
it must be produced by a ribosome on the rough ER and sent to the golgi apparatus
It must be produced by a ribosome in the golgi apparatus and sent to the rough ER.
The image shows part of a polypeptide. What determines the order in which the amino acids are connected to each other in the polypeptide?
the chemical structure of each R-group in the amino acid
the order of the the nitrogenous bases in a gene
the random nature of ribosome function
the sequence of amino acids that make up the gene
What is a promoter?
Sequence of DNA at the beginning of the gene that tells RNA polymerase where to start transcription.
Sequence of RNA that tells the ribosome where to start translation.
Sequence of DNA at the beginning of the gene that tells the ribosome where to start transcription
Sequence of RNA that tells RNA polymerase where to start translation.
Question
What is a gene
A long length of DNA that codes for a chromosome
A short length of DNA that codes for a chromosome
A short length of DNA that codes for a protein.
The number of human chromosomes is
23
46
92
64
From smallest to largest how would genetic information be organized?
genes, cell, nucleus, chromosome, DNA
chromosome, cell, gene, DNA, nucleus
DNA, gene, chromosome, nucleus, cell
nucleus, cell, gene, DNA, chromosome
Which one is not chromosomal aberration
Deletion
Duplication
Insertion
Translocation
. In sickle-cell anaemia, ________________
valine is substituted with proline.
valine is substituted with glutamic acid.
glutamic acid is substituted with proline.
glutamic acid is substituted with valine.
Hydroxylamine is a mutagen. It converts cytosine to a compound which pairs up with
adenine. If DNA is treated with hydroxylamine, the mutation which results is an example
of a base ________
deletion
insertion.
inversion.
substitution.
One possible result of chromosomal breakage can be that a fragment reattaches to
the original chromosome in a reverse orientation. This is called ______________
deletion.
inversion
disjunction
translocation
Frameshift mutation is caused by base insertion or deletion except in the case where the number of base pair involved is
one
two
three
seven
Cri du Chat syndrome is due to
deletion at chromosome 9
deletion at chromosome 5
inversion at chromosome 2
duplication at chromosome 3
Errors during DNA replication, repair or recombination can lead to base-pair
substitutions. Such changes are called ____________________
A. conditional mutations.
A. mutagens.
spontaneous mutations
A. saltatory changes.
Non-disjunction involving the X chromosomes occurs during oogenesis and produces two kinds of eggs, XX and O (no X chromosomes). If normal sperms fertilize the two types of eggs, which are the possible genotypes produced?
XX AND XY
XYY AND XO
XXY AND XO
YY AND XO
Generally speaking, males have an XY chromosome, and females have an XX chromosome. However, not everyone is born this way.
What is it called when someone has an XXY chromosomes?
down syndrome
Klinefelter syndrome
Archaeopteryx
dinosaurs
Built models to determine that DNA was a double helix shape with base pairs A-T and G-C in rungs between the sugar/phosphate backbone of DNA.
Watson & Crick
Franklin
Wilkins
Pauling
Chargaff
Worked on DNA imaging techniques and published Franklin's x-ray crystallography image of DNA
Watson & Crick
Franklin
Wilkins
Pauling
Chargaff
Provided clear x-ray crystallography images of DNA
Watson & Crick
Franklin
Wilkins
Pauling
Chargaff
One of the first scientists to use x-ray crystallography to observe DNA, hypothesized that there was a helix shape
Watson & Crick
Franklin
Wilkins
Pauling
Chargaff
Discovered that there was the same amount of A and T in a cell, and C and G in a cell.
Watson & Crick
Franklin
Wilkins
Pauling
Chargaff
Using x-ray diffraction to determine the structure of a crystal, such as DNA
x-ray crystallography
gas chromatography
chromatography
gel electrophoresis
A pair of parallel strands that twist together about an axis
nucleotide
double helix
base pair
esther bonds
basic structural unit of DNA. Examples: adenine, guanine, cytosine, thymine
nucleotide
phosphate
ribose sugar
enzyme
basic structural unit of DNA. Examples: adenine, guanine, cytosine, thymine
nucleotide
phosphate
ribose sugar
enzyme
5 carbon sugars and phosphates linked together through chemical bonds to provide the structural framework for nucleotides
chromosome
nucleotide
phosphate-sugar backbone
enzyme
Base pairs (correctly matched)
A-G and C-T
A-C and G-T
A-T and G-C
C-A and T-G
made up of a long strand of DNA that is bonded to proteins in a way that makes them condense/fold to form chromosomes
genetics
chromosome
proteins
DNA
a piece of a chromosome that is composed of specific nucleotide sequences of DNA
chromatid
nucleotide
gene
circular DNA
REVIEW: The property of water that allows for plants to carry water from the soil, through roots and stems, to leaves
pH (neutral, acidic, basic)
hydrogen bonding (adhesion, cohesion)
polarity (soluble, insoluble)
temperature (high heat capacity, solid water's density)
REVIEW: when cells take in oxygen and glucose and convert them into water, carbon dioxide, and ATP energy
DNA synthesis
cellular respiration
breathing
photosynthesis
deoxyribonucleic acid: the molecule that contains the basic instructions for life.
gene
chromosome
DNA
nucleotide
Factory for making a protein
mRNA
rRNA
tRNA
Carries the amino acid used to make a protein
mRNA
rRNA
tRNA
Where does transcription occur?
Cytoplasm
Mitochondria
Nucleus
ER
This image shows a picture of a ribosome - what type of RNA is this?
rRNA
mRNA
tRNA
What type of RNA is shown in this image?
rRNA
mRNA
tRNA
What type of RNA is shown in this image?
rRNA
mRNA
tRNA
Identify.
DNA
mRNA
rRNA
tRNA
Identify.
DNA
mRNA
rRNA
tRNA
Identify.
DNA
mRNA
tRNA
rRNA
Three consecutive nucleotides on a tRNA molecule
Translation
Transcription
anticodon
codon
Three consecutive nucleotides on a mRNA molecule
Translation
Transcription
anticodon
codon
3'-GCT-5'
T-G-A-C-C-A
T-G-A-C-C-A-A
AGA-TTC-ATA-GCG
Mutant-
AGA-TTC-AAT-AGC-G
The mutated DNA segment is TTACGCAAC. This is an example of ___ mutation.
A change in a gene, group of genes or chromosome that results in a change in the proteins
Replication
Mutations
Translation
Transcription
One nucleotide base is changed so only one amino acid
is affected
Substitution Mutation
Point Mutation
Translocation
Inverse Mutation
A substitution mutation that has no effect
on amino acids sequence
Insertion Mutation
Translocation
Silent Mutation
Deletion Mutation
A mutation that results in an amino acid change
Translocation
Homeostasis
Silent Mutation
Expressed Mutation
A nucleotide base is inserted or deleted shifting the entire DNA sequence. Entire protein will be changed.
Substitution Mutation
Silent Mutation
Frameshift Mutation
Translocation
Mutations that involve parts of or all of
a chromosome
Replication
Deletion Mutation
Chromosomal Mutation
Transcription
A point mutation where DNA adenine (A)
is replaced by thymine (T) resulting in a single amino acid change during translation(affects blood cell
shape and function)
Encephelitis
Hemophilia
Sickle Cell Anemia
Influenza
True or false, mutations create genetic diversity?
True
False
Mutations are SOMETIMES helpful to the organism.
true
false
Mutations are random.
True
False
Genetic Engineering is...
The manipulation of an organism's genes
The manipulation of an organism's chromosomes
Having 2 sets of chromosomes is called what?
Diploid
Haploid
Where does non-disjunction occur?
Metaphase
Anaphase
Prophase
Telophase
Which is NOT a condition that arises from non disjunction?
Klinefelter Syndrome
Down Syndrome
Turner’s Syndrome
Hurler Syndrome
Having 2 sets of chromosomes is called what?
Diploid
Haploid
What is another name for down syndrome?
Trisomy 18
Trisomy 21
Trisomy 13
Trisomy 23
What is non-disjunction?
Unable to form cells
Unable to form chromosomes
Unable to separate cells
Unable separate chromosomes
The presence of an abnormal number of chromosomes in a cell is called
Euploidy
Aneuploidy
Monoploidy
Polyploidy
Non-disjunction occurs in
Only mitosis
Only meiosis
Both mitosis and meiosis
If non disjunction occurs in meiosis 2, what is not separated?
Homologous chromosomes
Sister chromatids
Non disjunction in what phase causes all gametes to be abnormal?
Anaphase 1
Anaphase 2
A ______________ is created when chromosomes (homologous pairs) are grouped in ordered pairs and photographed.
pedigree
Punnett Square
Venn Diagram
Karyotype
Analyze the karyotype and determine the type of the non-disjunction that is shown.
This karyotype shows Trisomy 21
This karyotype has no abnormality
This karyotype shows a monosomy at the location of the sex chromosome
This karyotype shows a translocation at location 1 of the karyotype.
Which of the following would be considered a Gamete cell?
Egg Cell
Sperm Cell
Both of these
None of these
A pair of identical chromosomes shown in a karyotype, one inherited from the female, and one inherited from the male are called
sister chromotids
centromeres
homologous chromosomes
autosomes
Chromosome mutation involving a segment of a chromosome breaking off and attaching to a non-homologous chromosome.
Deletion
Inversion
Translocation
Duplication
What process occurs during meiosis that can result in chromosomal disorders?
crossing over
non-disjunction
anaphase I
prophase II
Non-disjunctions usually happen during which stage of meiosis?
Anaphase I- When Homologous Pairs do not separate correctly
Anaphase II- When Chromosomes do not separate correctly
Metaphase I- When Homologous Pairs do not condense
Prophase II- When Spindle Fibers do not form
Which response describes the behavior of chromosomes in metaphase I and Anaphase II of meiosis
A
B
C
D
T/F: A zygote is a sex cell.
Truee
False
Humans have a total of how many diploid chromosomes?
23 pairs
22 pairs
48 chromosomes
22 individual chromosomes
How is the doubling of chromosomes prevented in each generation?
Meiosis is a halving mechanism
Mitosis occurs
Body cells combine to form a zygote
All gametes are diploid
This is the attachment point between two sister chromatids
Centromere
Centriole
Chromatid
Chiasma
Crossing over results in... (select all that apply)
Genetic mutation
Recombination of alleles
Genetic diversity
Non-homologous chromosomes trading places
T/F: Crossing over increases genetic variation through recombination, leading to more variety in gametes (sex cells).
True
False
This image shows...
Two separate chromosomes
A bivalent
One pair of sister chromatids
Homologous chromosomes
Identify the phase
Prophase I
Anaphase II
Prophase II
Telophase II
What leads to the vast genetic diversity on our planet? (Select all that apply)
Crossing over
Random orientation
Mutations
Mitosis
What is non-disjunction?
A failure of chromosomes to separate at anaphase.
A hip new pop band.
When chromosomes pair up at the equator.
When chromosomes separate at anaphase
What is trisomy 21?
Too many chromosomes at Chromosome 21 (Down Syndrome)
Too many chromosomes at Chromosome X (Triple X- Syndrome)
A single chromosome at Chromosome 21
Non-disjunction of Chromosome 56
What is Mendel's Law of Independent Assortment?
Just because you get one allele for one gene, doesn't mean you'll get another allele for another gene. The genes are unlinked.
All genes come together regardless of where they are or what chromosome they are on.
All alleles are the same for the same species.
Gametes are guaranteed to get specific alleles on on every single chromosome.
How long does a cell spend dividing?
1 hour
24 hours
1 week
Depends on the type of cell
If a cell has 24 chromosomes, how many sister chromatids does it have?
24
12
48
92
Which part of the chromosome holds the sister chromatids together?
centromere
centriole
chromatin
DNA
What are the two parts of mitotic division?
interphase and mitosis
interphase and cytokinesis
mitosis and cytokinesis
What are the two phases of the cell cycle?
Interphase and Mitotic Division
Mitosis and Cytokinesis
Interphase and Cytokinesis
Metaphase and Interphase
What is being replicated (copied) during interphase?
DNA
mitochondria
glucose
lysosomes
Why must all DNA be copied during interphase?
So each new daughter cell can transport materials for homeostasis.
To release ATP.
So each new cell with have identical information and the cell can function properly.
Why is cell division important for the body?
To get the right amount of water.
To get the right amount on oxygen.
To replace old cells or repair injured tissue.
What is recombinant DNA
DNA from 2 different organisms combined
DNA from 2 different ribosomes
DNA that is separated out from a vector
Which of the following could be used as a vector for a human gene?
Bacterial Plasmid
Bacteria
A mitochondria
mRNA
In which ways can genetic engineering can improve crops
Make them pest or drought resistant
Make them more nutritious
Make them larger
All answers are correct
A circular piece of DNA, found in bacteria, is called:
A plasmid
mRNA
Ribosome
Nucleotide
