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Worksheets

Pediatric Dosing

Total questions: 21

Worksheet time: 17mins

Name
Class
Date
1.

You are writing an Rx for a child weighing 27lbs. What is the child's weight in kg?

a)

12.27

b)

10.81

c)

14.95

d)

27.32

2.

To convert lbs to kg you should take the weight in pounds and _____

a)

divide by 2.2

b)

multiply by 2.2

c)

subtract 2.2

d)

add 2.2

3.

Neonatal gastric pH is usually around?

a)

6-8

b)

8-10

c)

4-6

d)

1.5-3.5

4.

Due to increased neonatal pH this results in _____ bioavailability of acid-labile drugs such as ampicillin and nafcillin

a)

increased

b)

decreased

5.

Children's Benadryl (diphenhydramine) is a weak base with a pKa of 8.8. Newborns that are given children's Benadryl (not recommended) will have what absorptive effect?

a)

Increased

b)

Decreased

6.

Drugs that are administered via IM will have what effect on absorption?

a)

Increased

b)

Decreased

7.

Infants and children have greater levels of skin hydration and a thinner stratum corneum resulting in decreased absorption compared to adults

a)

True

b)

False

8.

Infants have a higher percentage of water and lower percentage of body fat. This results in _____ distribution of water soluble drugs and _____ distribution of lipophilic drugs.

a)

Increased, Increased

b)

Decreased, Decreased

c)

Increased, Decreased

d)

Decreased, Increased

9.

Due to a decreased number of CYP450 enzymes, infant metabolism is slower with slower hepatic clearance when compared to adults.

a)

True

b)

False

10.

CrCl and GFR decreases with age with peak being at birth resulting in quick renal excretion of medications.

a)

True

b)

False

11.

Calculating pediatric dose based from adult dosing based on age is known as?


Peds dose = [age/(age+12)] * adult dose

a)

Young's rule

b)

Clark's rule

c)

Body surface area

12.

Calculating pediatric dose based from adult dosing based on weight is known as?


Peds dose = (weight in lbs/150) * adult dose

a)

Young's rule

b)

Clark's rule

c)

Body surface area

13.

1 teaspoon is approximately equal to how many mL?

a)

~1mL

b)

~2mL

c)

~3mL

d)

~4mL

e)

~5mL

14.

15mL is approximately equal to which of the following?

a)

1 teaspoon

b)

1 tablespoon

c)

1 cup

d)

1 fl oz

15.

Which of the following drugs is not contraindicated for pediatric use

a)

Tetracyclines

b)

ASA

c)

Sulfonamides

d)

SSRIs

e)

Acetaminophen

16.

Both codeine and promethazine are contraindicated in pediatric use due to risk of which of the following?

a)

Growth suppression

b)

Cartilage toxicity

c)

Tooth discoloration

d)

Kernicterus

e)

Respiratory depression

17.

A mother presents with her child who has been febrile for the past 4 days. After evaluation you recommend symptomatic tx with Tylenol. The pediatric recommended dose of liquid Tylenol is 10-15 mg/kg/dose. You should recommend what mg/kg/dose of Tylenol to the mother?

a)

10mg/kg/dose

b)

12.5 mg/kg/dose

c)

15 mg/kg dose

d)

18 mg/kg/dose

e)

9 mg/kg/dose

18.

Tylenol recommended pediatric dosing is 10-15mg/kg/dose PO q4-6hr. Recommend the daily dose for a 22lb child who will be given the 160mg/5mL strength TID.

a)

12 mL/day

b)

4 mL/day

c)

25 mL/day

d)

120mL/day

19.

Tylenol recommended pediatric dosing is 10-15mg/kg/dose PO q4-6hr. Recommend the daily dose for a 43lb child who will be given the 500mg/5mL strength q4 hrs.

a)

14.6 mL/day

b)

2,44 mL/day

c)

25 mL/day

d)

1221.5 mL/day

20.

Amoxicillin recommended pediatric dosing for AOM is 80-90mg/kg/day PO q8-12hr. Recommend the daily dose for a 31lb child who will be given the 250mg/5mL strength BID.

a)

24 mL/day

b)

250 mL/day

c)

1198 mL/day

d)

12 mL/day

21.

Amoxicillin recommended pediatric dosing for AOM is 80-90mg/kg/day PO q8-12hr. Recommend the single dose for a 28lb child who will be given the 400mg/5mL strength.

a)

6.75 mL/dose

b)

13.5 mL/dose

c)

10.63 mL/dose

d)

5.51 mL/dose