WorksheetsGI Physiology Review
Total questions: 23
Worksheet time: 18mins
Which of the following substances is
released from neurons in the GI tract and
produces smooth muscle relaxation?
Secretin
Gastrin
CCK
VIP
GIP
Which of the following is the site of
secretion of intrinsic factor?
Gastric Antrum
Gastric Fundus
Duodenum
Ileum
Colon
Vibrio cholerae causes diarrhea because it
Increases HC03- secretory channels in
intestinal epithelial cells
increases CI- secretory channels in crypt
cells
prevents the absorption of glucose and
causes water to be retained in the intestinal
lumen isosmotically
inhibits cyclic adenosine monophosphate
(cAMP) production in intestinal
epithelial cells
inhibits inositoll,4,5-triphosphate (IP3)
production in intestinal epithelial cells
Cholecystokinin (CCK) has some gastrin like
properties because both CCK and
gastrin
are released from G cells in the stomach
are released from I cells in the
duodenum
are members of the secretin-homologous
family
have five identical C-terminal amino
acids
have 90% homology of their amino acids
Which of the following is transported in
intestinal epithelial cells by aNa+ -dependent
co transport process?Which of the following is transported in
intestinal epithelial cells by aNa+ -dependent
co transport process?
Fatty acids
Triglycerides
Fructose
Alanine
Oligopeptides
A 49-year-old male patient with severe
Crohn disease has been unresponsive to
drug therapy and undergoes ileal resection.
After the surgery, he will have steatorrhea
because
the liver bile acid pool increases
chylomicrons do not form in the intestinal lumen
micelles do not form in the intestinal
lumen
dietary triglycerides cannot be
digested
the pancreas does not secrete lipase
Cholecystokinin (CCK) inhibits
gastric emptying
pancreatic HC03- secretion
pancreatic enzyme secretion
contraction of the gallbladder
relaxation of the sphincter of Oddi
Which of the following abolishes
"receptive relaxation" of the stomach?
Parasympathetic stimulation
) Sympathetic stimulation
Vagotomy
Administration of gastrin
Administration of vasoactive intestinal
peptide (VIP)
Secretion of which of the following substances
is inhibited by low pH?
Secretin
Gastrin
Cholecystokinin (CCK)
Vasoactive intestinal peptide (VIP)
Gastric inhibitory peptide (GIP)
Which of the following is the site of
secretion of gastrin?
Gastric antrum
Fundus
Duodenum
Ileum
Colon
Micelle formation is necessary for the
intestinal absorption of
glycerol
galactose
vitamin D
Bile salts
Which of the following changes occurs
during defecation?
Internal anal sphincter is relaxed
External anal sphincter is contracted
Rectal smooth muscle is relaxed
Intra-abdominal pressure is lower than
when at rest
Segmentation contractions predominate
Which of the following is characteristic
of saliva?
Hypotonicity relative to plasma
A lower HC03- concentration than plasma
The presence of proteases
Secretion rate that is increased by
vagotomy
Modification by the salivary ductal cells
involves reabsorption ofK+ and HC03-
Which of the following substances is
secreted in response to an oral glucose load?
Secretin
Gastrin
CCk
VIP
GIP
Which of the following is true about the
secretion from the exocrine pancreas?
It has a higher CI- concentration than
does plasma
It is stimulated by the presence ofHC03-
in the duodenum
Pancreatic HCQ3- secretion is increased
by gastrin
Pancreatic enzyme secretion is increased
by cholecystokinin {CCK)
It is hypotonic
Which of the following substances must
be further digested before it can be absorbed
by specific carriers in intestinal cells'?
Fructose
Sucrose
Alanine
Dipeptides
Tripeptides
Slow waves in small intestinal smooth
muscle cells are
action potentials
phasic contractions
tonic contractions
oscillating resting membrane
potentials
oscillating release of cholecystokinin
(CCK)
A 24-year-old male graduate student
participates in a clinical research study on
intestinal motility. Peristalsis of the small
intestine
mixes the food bolus
is coordinated by the central nervous
system (CNS)
involves contraction of circular smooth
muscle behind and in front of the food
bolus
involves contraction of circular smooth
muscle behind the food bolus and relaxation
of circular smooth muscle in front
of the bolus
involves relaxation of circular and longitudinal
smooth muscle simultaneously
throughout the small intestine
A 38-year-old male patient with a
duodenal ulcer is treated successfully
with the drug cimetidine. The basis for
cimetidine's inhibition of gastric H
secretion is that it
blocks muscarinic receptors on parietal
cells
blocks H2 receptors on parietal cells
increases intracellular cyclic adenosine
monophosphate (cAMP) levels
blocks H+,K+-adenosine triphosphatase
(ATPase)
enhances the action of acetylcholine
(ACh) on parietal cells
Which of the following substances inhibits
gastric emptying?
Secretin
Gastrin
CCK
VIP
GIP
When parietal cells are stimulated, they
secrete
HCl and intrinsic factor
HCl and pepsinogen
HCl and HC03-
HC03- and intrinsic factor
mucus and pepsinogen
A 44-year-old woman is diagnosed with
Zollinger-Ellison syndrome. Which of the
following findings is consistent with the
diagnosis?
Decreased serum gastrin levels
increased serum insulin levels
Increased absorption of dietary lipids
Decreased parietal cell mass
Peptic ulcer disease
Which of the following is the site of
Na+-bile acid cotransport?
Antrum
Fundus
Duodenum
Ileum
Colon
