Calculate ANC: PMNs 33%, bands 8%, WBC 4000

Calculate ANC: PMNs 20%, bands 9%, WBC 3300

A patient is found to have febrile neutropenia (current temp 102 F, ANC 380). The source of infection is currently unidentified but they have received empiric antimicrobials within an hour. What tool do you use to evaluate for a source?

Which of the following isn't a gram-positive bacteria common for early febrile neutropenia?

Which of the following are gram-negative causes of early febrile neutropenia?

JK is a 56 year old sedated neuro patient being evaluated for febrile neutropenia. They are considered immunocompromised, febrile @ 103 F, and neutropenic @ 250 ANC. On examination, they have easily noticeable inflammation, erythema, and swelling around their central line. Their oral cavity also shows redness hinting at GI mucositis and the beginning of some white spots. What pathogen is most likely here?

What is the single most important goal of febrile neutropenia management?

Which of the following would put an FN patient into high risk?

YU is a recently admitted 70 year old female with a recent ANC of 480 and a current fever of 102F. They are believed to have developed an infection from a grandbaby with influenza. YU is expected to decline to an ANC of 200 for a short period while treatment takes effect. Their ACOG score is 1 due to hip pain restricting activity lightly. Their outpatient medications include Tylenol, Pepcid, Motrin, Allegra, and alemtuzumab. What risk category are they in and what empiric treatment do you recommend?

Should daptomycin be used in lung infections?

A low risk febrile neutropenia patient is finishing up at your clinic. They are qualified for outpatient po treatment. Their MASCC is 21, ECOG 0, and they don't have any major ongoing comorbidities. Their medications in the past two weeks have included Zicam, pseudoephedrine, Tylenol, levofloxacin, lisinopril, and Norco. They have a severe allergy to amoxicillin. What medication do you recommend for their febrile neutropenia?

A physician asks for a consult on their severe febrile neutropenia patient. The patient is in the ICU with profound and prolonged neutropenia. The causative pathogen is unknown but Pseudomonas and MRSA should be included in the coverage. The physician has asked for a course of Ertapenem and Vancomycin IV until the pathogen is confirmed. Is this acceptable?

Which pathogen is incorrectly matched to its drug(s) of choice?

OP is a 32 year old ICU patient with a high risk Pseudomonas aeruginosa respiratory infection. Their ANC is 187 and their fever is high. What is the best recommendation for OP?

Which of the following would be useful for treating E. coli bacteremia causing febrile neutropenia?