Are the most often consideration when red blood cells are used as the carrier particle

The reaction where the red blood cells are the indicator particles

These particles are inexpensive, stable and are not subject to cross-reactivity with other antibodies

The use of semi-synthetic beads or particles provides the advantage of consistency, uniformity and stablity

If the sample has no free hapten, the reagent antibody is able to combine with the ___ and produce a visible agglutination

Systems using bacteria as the inert particles to which antibody is attached is called Coagglutination

This is a technique that detects non-agglutinating antibody by means of coupling with a second antibody also called Indirect Coomb's test

It is used to demonstrate in vivo attachment of antibody or complement to an individual's red blood cells.

Agglutination is the visible aggregation of particles caused by combination with two specific antibody

Sensitization step involves antigen-antibody combination through single ___ determinants on the particle surface.

Passive agglutination employs particles which are coated with antigens not normally found on their surfaces

Agglutination inhibition reactions are based on the ___ between particulate and soluble antigens for limited antibody-combining sites.

Heterophile antibody and rheumatoid factors are two interfering antibodies that may produce a false-positive result.

Coomb's test is the most widely used procedure in blood banking

This type of testing is used to detect antibodies to certain viruses such as rubella, mumps, measles, herpes virus and adenovirus

The use of ___ has greatly cut down on cross-reactivity, but there i still a possibility of interference

Quality Control and Quality Assurance must standardize method of reading, incubation time, concentration of antigen temperature and diluent

This protein naturally absorbs the FC portion of antibody molecules which is found in staphylococcus aureus

Antigenics that produce such reaction are often called Agglutinins which involves sensitization followed by lattice formation