WorksheetsMICR 187 LO9 Review - Microbiology Antimicrobials
Total questions: 30
Worksheet time: 18mins
Which option represents the definition of mode of action?
Targets Gram positive organisms
Cell wall synthesis inhibitor
Bacteriostatic drug
Which antibiotic group contains drugs with a beta-lactam ring?
Cell membrane inhibitors
RNA synthesis inhibitors
Protein synthesis inhibitors
Cell wall synthesis inhibitors
Which organism gains resistance by the presence of the mecA gene?
VRE
ESBL
MRSA
PBP2
What is the most common antimicrobial from the glycopeptide group?
(a)
What type of infection should nitrofurantoin be used for?
Anaerobic infection
Urinary tract infection
Blood stream infection
Gastrointestinal tract infection
What drug is only appropriate for anaerobic infections?
Vancomycin
Penicillin
Clindamycin
Metronidazole
What is the only drug that inhibits RNA synthesis?
(a)
Which two drugs are used in combination to target the folic acid pathway?
Sulfonamides
Nitrofurantoin
Penicillin
Trimethoprim
What is the name of the cell wall protein to which beta-lactam drugs bind?
(a)
True or False? Vancomycin is active against Gram negative organisms.
True
False
What is the treatment of choice for Vancomycin-resistant Enterococcus (VRE)?
(a)
Which group of drugs will not work for a patient which an infection from Mycoplasma sp.?
Beta-lactams
Aminoglycosides
Sulfonamides
Trimethoprims
What is the treatment of choice for Neisseria meningitidis?
SXT
Erythromycin
Penicillin
Ciprofloxacin
What is the treatment of choice for Enterobacterales?
Ampicillin
Vancomycin
Metronidazole
Erythromycin
What is the most common media used for Kirby-Bauer testing?
(a)
How many planes are required when swabbing a suspension over a KB MH plate?
1
2
3
4
A bacterial suspension is made in saline to 0.5 McF equivalent. It is left to sit for 45 minutes before the tech finishes setting up the KB test. What will be the result of the zones of inhibition after incubation?
Falsely increased
No change
Falsely decreased
What genus demonstrates growth that can be ignored within the zone of inhibition for the KB test?
(a)
An isolate of Escherichia coli is sent for KB testing. How long should the MH plate be incubated?
12-14 hours
16-18 hours
20-24 hours
24 hours
An isolate of Streptococcus pneumoniae is sent for KB testing. How long should the MH with blood plate be incubated?
12-14 hours
16-18 hours
20-24 hours
24 hours
An isolate of suspect Methicillin resistant Staphylococcus aureus is sent for KB testing. How long should the MH plate be incubated?
12-14 hours
16-18 hours
20-24 hours
24 hours
What method is NOT appropriate for testing suspect colonies of Staphylococcus aureus for methicillin resistance?
Cefoxitin e-strip
Cefoxitin disk
Oxacillin e-strip
Oxacillin disk
What incubation atmosphere is required for all KB tests set up on HTM media?
Aerobic
Anaerobic
Capnophilic
Microaerophilic
What unit is required when recording a result from an epsilometer strip?
mm
mm/mL
ug
ug/mL
If the growth of an organism intersects on an e-strip between two numbers, which number should be recorded?
Higher concentration
Lower concentration
What test can be used to detect the presence of a beta-lactamase in an organism?
(a)
What is the name given to organisms that display resistance to extended spectrum beta-lactam drugs?
MRSA
VRE
ESBL
CPO
What is the screening method used to detect resistance to third-generation cephalosporins?
ESBL disk screen
PBP2a
Vancomycin screen
What gene is responsible for inducible clindamycin resistance?
mecA
erm
vanA/B/C
esb
Which two drugs are used in the D-zone test?
Ampicillin
Clindamycin
Erythromycin
Gentamicin
