WorksheetsU4L3 - Mutations
Total questions: 17
Worksheet time: 19mins
What mutation has occurred here?
T-G-A-C-C-A
T-G-A-G-C-A
Substitution
Deletion
Insertion
Frameshift
DNA molecule segment is : TTACGCAAG
The mutated DNA segment is TTACGCAAC. This is an example of ___ mutation.
Substitution
Insertion
Inversion
Translocation
ATT-TGA-GCC- Original
ATT-GAG-CC - Mutated
The example above is an example of a
Insertion- Frameshift
Deletion- Substitution
Deletion -Frameshift
All of the above
DNA molecule segment is : TTA-CGC-AAG
The mutated DNA segment is TTC-GCA-AG. This is an example of ___ mutation.
Substitution
Deletion
Insertion
Inversion
Original DNA: CAT GAT CCA
New DNA: CAT TGA TCC A
What mutation occurred?
deletion
substitution
tranverse
insertion
Mutation: ATC GCAT
What mutation occurred?
What type of gene mutation has occurred here? Normal-
AGA-TTC-ATA-GCG
Mutant-
AGA-TTC-AAT-AGC-G
deletion frameshift
insertion frameshift
substitution
nonsense
Why are insertion and deletion mutations so harmful?
They change all of the codons from the mutation on down the line, which changes the amino acid sequence
They insert things that an organism doesn't need.
They often delete things that organisms need.
Insertion and deletions are not any more harmful than substitution mutations.
Which of the following is true regarding substitution mutations ...
a missense mutation. This could affect the 3D structure of the protein.
a silent mutation. The mutation causes no effect as the first mRNA codon still codes for the same amino acid even though the base has been substituted.
a nonsense mutation. The mutation causes the second mRNA codon to become a stop codon, which means it stops synthesis of the amino acid chain prematurely. This will likely result in a non-functional protein.
frameshift mutation. This causes all of the amino acids shown to change. This will cause a non-functional protein.
have no effect on the amino acids produced during protein synthesis.
silent mutation
causes a stop codon instead of a normal amino acid codon. This causes translation to be terminated prematurely, causing a shorter protein.
nonsense mutation
causes a codon to code for a different amino acid than the original one.
missence mutation
causes the “reading frame” of the codons to shift forwards or backwards. This can change the entire sequence of amino acids.
frameshift mutation
causes a change to one base and potentially one amino acid of the polypeptide chain
point mutation
Label each of the following chromosomal mutations
Identify which of the following are true and which are false
