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RESPIRATORY SYSTEM: MICROBIOLOGY, PHARMACOLOGY AND VIROLGY 2

Total questions: 20

Worksheet time: 14mins

Name
Class
Date
1.

A 40 year old man reports to casualty. He was previously diagnosed with community acquired pneumonia. On examination he is confused, and respiratory rate of 32 bpm blood preessure of 86/58 mmHg. what is the CRB-65 score for this patient?

a)

0

b)

1

c)

3

d)

4

2.

Which of the following factors does not determine the likelihood of TB transmission?

a)

immune status of the person

b)

time exposed to the TB contaminated air

c)

sitting with a patient who was diagnosed with TB and taking her medications for 3 months

d)

Number of organism expelled into the air

3.

Which of the following is an advantage of microscopy in diagnosis of TB.

a)

monitoring treatment success

b)

low sensitivity

c)

cannot detect drug resistance

d)

Does not distinguish mycobacteria spp

4.

Which of the following microbiological diagnosis in phenotypic tests is gold standard in diagnosing drug resistance TB?

a)

microscopy

b)

Culture

c)

DNA extraction

d)

Line probe assay

5.

Which of the following is NOT challenge of TB diagnosis.

a)

lost specimen

b)

specimen labelled correctly

c)

poor quality sputum

d)

contaminated sputum

6.

It is defined as a pneumonia not incubating at the time of hospital admission and occurring 48 hours and more after admission

(a)  

7.

Which of the following is the commonest cause of community acquired pneumonia

a)

Streptococcus pneumonia

b)

pseudomonas aeroginosa

c)

legionella

d)

Mycoplasma pneumonia

8.

What is the major virulence determinant in streptococcus pneumoniae which interferes with complement deposition on the organism thus preventing phagocyte recognition and engulfment

(a)  

9.

Pertusis commonly affects...

a)

teenagers

b)

middle aged

c)

infants

d)

Septugenarians

10.

A 4 year old boy boy was brought to casualty department by his father. He complained of fever, malaise and sneezing. He later developed paroxysmal coughing, which are typoically worse at night. what is the most likely diagnosis?

a)

Bordetella pertusis

b)

intestinal malrotation

c)

Tubercolosis

d)

Pyrexia

11.

It is defined as microorganisms that live on another organism(human or animal) without causing disease.

(a)  

12.

The following drug is a cell wall synthesis inhibitor

a)

penicillin

b)

gentamycin

c)

ciprofloxacin

d)

erythromycin

13.

Which of the following is not a characteristic of of mycobacterium tuberculosis

a)

Acid fast bacillus

b)

mycolic acids within cell wall

c)

slow growing

d)

anaerobic

14.

Which of the following is a cough suppressant

a)

Antitussive

b)

Expectorants

c)

mucolytic

d)

mucokinetics

15.

In phase 2 of TB treatment which 2 drugs are used over a period of 4 months?

a)

Rifampicin and isoniazid

b)

Rifampicin and ethambutol

c)

Rifampicin and Erythromycin

d)

Streptomycin and Pyrazinamide

16.

Complicated form of Extra-pulmonary tubercolosis is treated for how long

a)

4 months

b)

7 months

c)

6 months

d)

9 months

17.

In 1957 the H2N2 influenza A pandemic that killed 2 million people was also known as...

a)

Spanish influenza

b)

Asian flu

c)

Hong kong flu

d)

swine flu

18.

The abrupt change of antigenicicity due to genetic reassortment between two viruses from different host species producing a novel virus, also causes pandemics.

(a)  

19.

Which of the following is not a factor affecting vaccine respond

a)

Age

b)

social status

c)

obesity

d)

chronic underlying conditions

20.

The process that results in the production of a new genome derived from two parental genomes.

(a)