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B6 Disease

Total questions: 25

Worksheet time: 14mins

Name
Class
Date
1.

What is a pathogen?

a)

A micro-organism.

b)

A macro-organism that causes disease.

c)

A micro-organism that causes disease.

2.

Special proteins produced by white blood cells (lymphocytes) to attack foreign invaders.

a)
antibodies
b)
antigen
3.

Proteins on the surface of pathogens that initiate an immune response.

a)
antibodies
b)
antigens
4.

Introduction into the body of a weakened, killed or piece of a disease-causing agent to prevent disease.

a)

vaccination

b)

immunity

5.
A vaccines main goal is to:
a)
make people sick
b)
prevent disease
c)
start an epidemic
d)
start a pandemic
6.
 Following a vaccination, the white cells produce . . .
a)
antibiotics
b)
antibodies
c)
statins.
d)
toxins.
7.

What is herd immunity

a)

When everyone is vaccinated.

b)

A form of immunity that occurs when the vaccination of a significant portion of a population provides a measure of protection for individuals who have not developed immunity.

c)

When all of a group of farm animals have been immunised.

d)

When a disease spreads throughout a population.

8.

Antibiotics are not effective against.....

a)

viruses

b)

bacteria

9.

Why is it bad to stop taking your antibiotic before the doctor recommends?

a)

not all of the bacteria is killed, possibly leading to resistance

b)

you will weaken your immune system

c)

you'll get MRSA

d)

you'll gain weight

10.

Why is antibiotic resistance a problem?

a)

Resistant bacteria give you different symptoms

b)

It is difficult to get rid of the infection

c)

Resistant bacteria are more harmful

11.
What is a placebo?
a)
A second type of drug given to all people in a trial
b)
A 'dummy' pill given to all people in the trial
c)
A 'dummy' pill given to half of the people in the trial
d)
A drug that will probably harm the patients taking it 
12.
What is a double blind trial?
a)
The participants take the drug blindfolded
b)
When the scientist and the participants are unaware of whether they are taking the drug or placebo
c)
When the participants choose what they want to take without telling the scientist
d)
When the scientist knows who is taking the drug but the participants don't
13.
Why are clinical drug trials important?
a)
They can improve the health of patients
b)
To understand whether the drug causes any harmful side effects
c)
They help test the effectiveness of the drug 
d)
To test whether the drug works and if it causes any harmful side effects
14.
Why are double blind trials important?
a)
They make sure the results are fair and unbiased
b)
If the scientist knows who has taken the drug they will lie or change results to show it works
c)
They are the only type of clinical trials available 
d)
Patients might lie about any side effects they feel 
15.
Why are placebos so important?
a)
To help understand if the drug actually makes any real difference
b)
It is too expensive to give all the people who want to volunteer the drug 
c)
To save some people from the risk of harmful side effects 
16.

Which drug originated from foxgloves?

a)

Cocaine

b)

Aspirin

c)

Ibuprofen

d)

Digitalis (heart drug)

17.

Which type of drug was first produced from the Penecillium mould?

a)

Stimulants

b)

Antiseptics

c)

Insulin

d)

Antibiotic

18.

A new drug will be tested for toxicity. What does that mean?

a)

Tested to see what benefits it has

b)

Tested to see if it works

c)

Tested to see how poisonous it is

19.

New drugs need to be tested for efficacy. What does efficacy mean?

a)

To see how toxic it is

b)

To see what side effects it has

c)

To see how well the drugs works

d)

To work out the drug cost

20.

Which types of testing is pre-clinical testing?

a)

Testing on cells only

b)

Testing on human volunteers

c)

Testing on mammals only

d)

Testing on cells, tissues or animals

21.

Which types of testing is clinical testing?

a)

Testing on cells only

b)

Testing on human volunteers

c)

Testing on mammals only

d)

Testing on cells, tissues or animals

22.

Why are only low doses of a new drug given to human volunteers in the first clinical trial?

a)

To check for any harmful side effects

b)

To work out what the ideal dose should be

23.

What are Monoclonal antibodies ?

a)

An antibody produced by the body.

b)

An antibody produced by a single clone of cells or cell line and consisting of identical antibody molecules.

c)

An antibody produced by a single clone of cells or cell line and consisting of many different antibody molecules.

d)

An antibody produced in a lab

24.
What is a hybridoma cell?
a)
A particular antibody
b)
A B lymphocyte fused with a cancer cell
c)
An antibody fused with a lymphocyte
d)
None of the above
25.
What is the first stage of producing monoclonal antibodies?
a)
Stimulating mouse lymphocytes to make an antibody
b)
collect spleen cells from a mouse
c)
Form hybridoma cells
d)
produce myeloma cells