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WorksheetsENDORENAL SPCS
Total questions: 18
Worksheet time: 10mins
According to ADA, at what age should screening for DM start?
35
50
55
None of the above
Which of the following supports the diagnosis of DM?
FPG 115 mg/dl
FPG 115 g/dl
OGTT 150 mg/dl
None of the above
What is the most common cause of Cushing’s syndrome?
ACTH-producing pituitary adenoma
Chronic use of glucocorticoids
Adrenocortical adenoma
Adrenocortical carcinoma
Effects of insulin include the ff. EXCEPT:
Promotes glucose storage as glycogen
Increased protein synthesis
Decreased triglyceride storage
Inhibits conversion of fatty acids and amino acids to keto acids
Which of the ff clinical features is most frequently seen in Cushing syndrome with any age?
Moon facies
Hirsutism
Truncal Obesity
Obesity
Which glucose transporter is responsible for insulin uptake of glucose into muscle and adipose tissues?
GLUT 2
GLUT 3
GLUT 4
GLUT 5
A sellar mass compressing the cavernous sinus would present with which of the following
Ophthalmoplegia with or without ptosis or diplopia
Facial numbness
All of the above
None of the above
This genetic syndrome typically presents with spotty skin pigmentation, myxomas, and endocrine tumors such as testicular, adrenal, and pituitary tumor
Carney complex
McCune Albright Syndrome
MEN1
None of the above
Which of the following class of drugs activates the enzyme AMP-activated protein kinase (AMPK) and reduce hepatic glucose production?
Biguanides
Sulfonylureas
Thiazolidinediones
Meglitinides
All of the following are treatment goals for adults with diabetes EXCEPT:
Preprandial capillary plasma glucose: 80-140 mg/dL
Postprandial capillary plasma glucose: <180 mg/dL
HbA1c: <7%
BP <140/90
Which of the ff statements about the changes in glucocorticoid blood levels is/are correct?
The changes in the blood levels vary throughout the day
The drop of blood levels occurs in the early morning hours
The rise of blood levels occurs in the early phase of sleep
All of the Above
A 50-year-old male was diagnosed with CT scan finding of pituitary adenoma. He has clinical features of hypogonadism and galactorrhea. Which of the ff is the probable cell origin?
Gonadotroph
Lactotroph
Mixed gonadotroph and lactotroph
Mammosomatotroph
Patient J.K. has the following lab results:
DEX overnight test >70 nmol/L
Plasma ACTH 25 pg/ml
What should be done next?
Perform unenhanced CT
Perform petrosal sinus sampling
Perform CRH test and high-dose DEX test
None of the above
A patient presents with persistent hypercortisolism despite undergoing transsphenoidal resection. What would be the appropriate treatment for the patient?
Mifepristone & ketoconazole
Pasireotide
Pituitary irradiation
All of the above
Which of the following is true regarding the fluid management of diabetic ketoacidosis?
2-3L of 0.9% saline over first 1-2h
Subsequently, 0.45% saline at 250-500mL/h
Then, change to 1% glucose and 0.45% saline at 150-250 mL/h when plasma glucose reaches 250 mg/dL
None of the Above
Which of the following inferior petrosal sinus sampling results favor an ectopic ACTh secretion
Basal IPSS: peripheral = 1
Basal IPSS: peripheral = 2
CRH-induced IPSS: peripheral = 3
CRH-induced IPSS: peripheral = 4
A 30-year-old male is diagnosed with Cushing’s disease with bilateral micronodular adrenal hyperplasia. Which of the ff is the recommended treatment?
Transsphenoidal pituitary surgery
Inferior adrenalectomy
Bilateral adrenalectomy
Unilateral adrenalectomy
Apart from glucose lowering actions, this agent lowers triglycerides and increases HDL cholesterol without affecting total cholesterol and LDL choles levels.
Rosiglitazone
Pioglitazone
Dapagliflozin
Empagliflozin
