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IT2 - Exam 4 TAN

Total questions: 34

Worksheet time: 21mins

Name
Class
Date
1.

Which of these describes the protein coat of the virus?

a)

Capsid

b)

Envelope

c)

Spikes/Envelope Glycoprotein

2.

Which of these describes a host derived phospholipid membrane that encapsulates the capsid. It contains proteins from both the host and the virus?

a)

Capsid

b)

Envelope

c)

Spikes/Envelope Glycoprotein

3.

A naked virus is lacking a...?

a)

Capsid

b)

Envelope

c)

Spikes/Envelope Glycoprotein

4.

A host derived phospholipid membrane that encapsulates the capside.

a)

Capsid

b)

Envelope

c)

Spikes/Envelope Glycoprotein

5.

determine the specificity (host range), virulence and antigenic properties of enveloped viruses. They are also used for recognition, attachment, fusion adn entry into host cells by way of specific host cell membrane receptors.

a)

Capsid

b)

Envelope

c)

Spikes/Envelope Glycoprotein

6.

What is true about viruses?

a)

Lack a cell wall and cell membrane

b)

They do not carry out metabolic processes

c)

They carry out metabolic processes

d)

Are living

e)

Are nonliving

7.

What is true about the viral replication process?

a)

Viruses hijack the transcriptional and metabolic machinery of the host

b)

The host cell may or may not be destroyed during viral replication

c)

Viruses are obligate intracellular parasites

d)

Viruses are aerobic parasites

e)

Viral replicative processes and host metabolic processes are very intimately associated

8.

What is true about the challenges for antiviral therapy?

a)

Few drugs are selective enough to prevent viral replication without injury to infected host cells.

b)

Nonselective inhibitors of virus replication interfere with host cell function and result in toxicity

c)

All drugs are active only when replicating. They do not affect latent viruses.

d)

Clinical sx appear late in course of the disease in which most of viral particles have replicated.

e)

Some antivirals can be used as prophylactic agents

9.

_________ of virus replication interfere w/ host cell function and result in toxicity.

a)

Nonselective inhibitors

b)

Selective inhibitors

c)

Antiviral therapy

d)

MHC Class 1

10.

Herpesviridae can cause:

a)

Herpes (HSV)

b)

CMV retinitis

c)

Chicken Pox

d)

Shingles

e)

Hep B

11.

Hepadnaviridae can cause:

a)

Hepatitis B

b)

Chicken Pox

c)

MERS

d)

Hemorrhagic fever

12.

Coronaviridae can cause:

a)

Covid-19

b)

Dengue

c)

AIDs

d)

Chicken Pox

13.

Flaviviridae can cause:

a)

Hep C

b)

Hep B

c)

Influenza

d)

Herpes

e)

AIDS

14.

Flaviviridae can cause:

a)

Dengue

b)

Encephilitis

c)

Yellow fever

d)

Hep C

e)

Erythema

15.

Orthomyxoviridae can cause:

a)

Influenza

b)

Rabies

c)

Rubella

d)

COVID

e)

Herpes

16.

Paramyxoviridae can cause:

a)

Measles

b)

Mumps

c)

Bronchiolitis/pneumonia (RSV)

d)

Rubella

e)

URI

17.

Picornaviridae can cause:

a)

Polio

b)

Diarrhea

c)

URI

d)

Hep A

e)

Hep B

18.

Retroviridae can cause:

a)

AIDS

b)

Rubella

c)

Dengue

d)

URI

e)

Chicken pox

19.

Rhabdoviridae can cause:

a)

Rubella

b)

Rabies

c)

Smallpox

d)

Dengue

e)

Encephalitis

20.

Togaviridae can cause:

a)

Rubella

b)

Rabies

c)

Measles

d)

Mumps

e)

Herpes

21.

Shingles in AIDS patients can lead to..

a)

Pneumonia

b)

Encephalitis

c)

Meningitis

d)

Rash

e)

Cold sores

22.

Herpes simplex virus 1 can result in:

a)

Cold sore

b)

Genital herpes

c)

Swollen gums

d)

Encephalitis

e)

Chicken Pox

23.

Herpes simplex virus 2 can result in:

a)

Cold sore

b)

Genital herpes

c)

Swollen gums

d)

Encephalitis

e)

Chicken Pox

24.

Varicella zoser can result in:

a)

Cold sore

b)

Genital herpes

c)

Swollen gums

d)

Shingles

e)

Chicken Pox

25.

A mononucleosis, no FDA-approved drugs; acyclovir is used off label, virus establishes latency in B-cells and can increase the risk of Burkitt's Lymphoma.. describes..

a)

Epstein-Barr

b)

HSV-1

c)

HSV-2

d)

Cytomegalovirus

e)

Roseolovirus

26.

Which topical drug interferes with viral entry for HSV?

a)

Docosanol (abreva)

b)

Valacyclovir

c)

Acyclovir

d)

Cidofovir

e)

Letermovir

27.

Which structure is this?

a)

Docosanol

b)

Acyclovir

c)

Valacyclovir

d)

Viroptic

e)

Ganciclovir

28.

What is true about Docosanol (Abreva)?

a)

Saturated long fatty chain alcohol

b)

OTC 10% topical cream for herpes

c)

Cannot be systemically absorbed

d)

Inhibits virus attachment/fusion

e)

Has a latent phase

29.

Which are CMV treatments?

a)

Ganciclovir

b)

Valganciclovir

c)

Acyclovir

d)

Penciclovir

e)

Trifluridine

30.

Which is a ophthalmic treatment for HSV?

a)

Trifluridine

b)

Famciclovir

c)

Penciclovir

d)

Ganciclovir

e)

Foscarnet

31.

True or false: Antiherpes drugs are tricyclic analogs of dGMP.

a)

False

b)

True

32.

True or false: Antiherpes drugs are acyclic analogs of dGMP.

a)

False

b)

True

33.

True or false: The substrates for DNA synthesis are nucleotide triphosphates.

a)

False

b)

True

34.

Which medication is used for HSV but is only used for opthalmic use?

a)

Trifluridine

b)

Famciclovir

c)

Penciclovir

d)

Valacyclovir

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