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WorksheetsJustoza Neev Program Quiz
Total questions: 23
Worksheet time: 23mins
NAME
HQ
REGION
Drug Master File (DMF) is a submission to the Food and Drug Administration (FDA) about the ___________________, processing, packaging, and storing of one or more human drugs.
Taxonomy
Manufacturing
Purification
All of the above
DMF grade API for formulation comes from ___________________________certified plants
USFDA
EUGMP
WHO
All of the Above
Kidneys reabsorb Glucose via which of the following transporters? (More than 1 Answer)
GLUT-4
GLUT-2
SGLT-1
SGLT-2
DAPA HF Trial had _____% pts who were Diabetic
44%
42%
45%
43%
Justoza provides ______% reduction in NTproBNP post 8 month of treatment
22
23
21
24
Increased Renal Glucose ___________________ May Contribute To Hyperglycemia In Diabetes.
Reabsorption
Excretion
Secretion
All of the above
SGLT2 Inhibitors _________________Renal Threshold for Glucose Excretion (RTG)
Decrease
Increase
SGLT-2i offer which of the following benefits. (More than 1 options can be correct)
Excess of Glucose is excreted through the Urine
Caloric Loss- Loss of Weight
Reduction in BP
Unique Insulin independent MOA
Dapagliflozin reduces CV Mortality by ___________% as per DAPA-HF
25
36
18
27
Dapagliflozin causes Hypoglycemia similar to Insulin
True
False
In patients with heart failure (NYHA II-IV) with reduced ejection fraction _______________reduces the risk of CV death and hospitalization for heart failure as per DAPA-HF Trial?
ARNI
Dapagliflozin
Canagliflozin
All of the above
Justoza is recommended by _______________as first line therapy in T2DM with CKD & HF
AHA Guidelines 2022
ADA Guidelines 2022
ACC Guidelines 2022
In patients with T2DM with established CVD or multiple CV risk factors, to reduce the risk of hospitalization for Heart Failure dapagliflozin was approved as per which trial?
DAPA HF
DAPA-CKD
DECLARE TIMI 58
All of the Above
As per the VA, Dapagliflozin is now indicated as Component of First-line therapy in HFrEF patients as per ____________________________.
2021 ACC Expert Consensus Decision Pathway.
ESC HF 2021 Guidelines
ACC HF 2021 Guidelines
All of the above
As per Dapa HF Study In HFrEF patients without Diabetes, Dapagliflozin showed _____% reduction in primary composite End point of CV death or Heart Failure Hospitalization
24
27
25
26
As per Dapa HF Study In HFrEF patients without Diabetes, Dapagliflozin showed _____% reduction in Hospitalization for Heart Failure
38
37
39
40
Justoza10 mg costing –
Rs. 9.90/tab
Rs. 7.50/tab
Rs.10.95 /tab
Justoza 5mg costing –
Rs. 9.90/tab
Rs. 7.50/tab
Rs.10.95 /tab
Declare-TIMI trial, the largest CVOT with an SGLT2i conducted on T2DM patients showed that in primary prevention patients, Dapagliflozin reduced the risk of HHF by ___________.
44%
26%
36%
32%
The Primary Composite Outcome of which trial is reduction in Sustained ≥50% eGFR Decline, ESKD, Renal or CV Death?
DAPA-HF
DAPA-CKD
DECLARE-TIMI
