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Day 14: Virulence Factors

Total questions: 10

Worksheet time: 5mins

Name
Class
Date
1.

Botulinum toxin is an example of a(n):

a)

Carbohydrate

b)

Exotoxin

c)

Endotoxin

d)

LPS

2.

Which of the following would be a sign of an infection?

a)

Muscle aches

b)

Fever

c)

Headache

d)

Dizziness

3.

The ______ is the time that lapses between encounter with a pathogen and the first symptoms

a)

Period of convalescence

b)

Period of invasion

c)

Period of incubation

d)

Prodromal period

4.

Endotoxins are associated with Gram-negative bacteria and are part of their cell _______ and are released when the cell ________/___________, while exotoxins are produced and released by Gram-positive and some Gram-negative bacteria and are called _________ if they affect the nervous system and _________ if they affect the digestive system.

a)

membrane; shrivels/enlarges; leukocidins; hemolysins

b)

walls; divides/dies; neurotoxins; enterotoxins

c)

cycle; shrivels/enlarges; hemolysins; leukocidins

d)

flagella; divides/dies; enterotoxins; neurotoxins

5.

A short period early in a disease that manifests with general malaise and achiness is the:

a)

Period of convalescence

b)

Period of incubation

c)

Prodromal period

d)

Period of invasion

6.

Which of the following applies to hyaluronidase?

a)

It acts as a spreading factor

b)

It is produced by immune cells to target pathogens

c)

It is an example of an adhesin

d)

It promotes blood clotting

7.

Pathogen A has an ID50 of 50 particles, Pathogen B has an ID50 of 1000 particles, and Pathogen C has an ID50 of 1X106 particles.  Which pathogen is most virulent?

a)

A

b)

B

c)

All are equally virulent

d)

C

8.

Which of the following is not a portal of entry for pathogens?

a)

Blood

b)

Parenteral route

c)

Mucous membranes of the respiratory tract

d)

Mucous membranes of the GI tract

9.

Which of the following choices lists the steps of pathogenesis in the correct order?

a)

invasion, infection, adhesion, exposure

b)

adhesion, exposure, infection, invasion

c)

exposure, adhesion, invasion, infection

d)

disease, infection, exposure, invasion

10.

A positive antibody test for HIV would be a ______ of infection

a)

Symptom

b)

Syndrome

c)

Sequela

d)

Sign