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Slow learner quiz_clinical_2021-22

Total questions: 15

Worksheet time: 8mins

Name
Class
Date
1.

Organogenesis occurs during

a)

Pre-embryonic.

b)

Embryonic.

c)

Pre-Fetal.

d)

Fetal.

2.

Tachyphylaxis is:

a)

A drug interaction between two similar types of drugs

b)

Very rapidly developing tolerance

c)

A decrease in responsiveness to a drug, taking days or weeks to

develop

d)

A drug interaction between two different types of drugs

3.

What is the type of drug-to-drug interaction which is connected with

processes of absorption, biotransformation, distribution and excretion?

a)

Pharmacodynamic interaction

b)

Physical and chemical interaction

c)

Pharmaceutical interaction

d)

Pharmacokinetic interaction

4.

A teratogenic action is:

a)

A. Toxic action on the liver

b)

B. Negative action on the fetus causing fetal malformation

c)

C. Toxic action on blood system

d)

D. Toxic action on kidneys

5.

Therapeutic index (TI) is:

a)

A. A ratio used to evaluate the safety and usefulness of a drug for

indication

b)

B. A ratio used to evaluate the effectiveness of a drug

c)

C. A ratio used to evaluate the bioavailability of a drug

d)

D. A ratio used to evaluate the elimination of a drug

6.

Indicate major role of clinical pharmacist

a)

A. Premarketing surveillance

b)

B. Post-marketing surveillance

c)

C. Preclinical study

d)

D. Patient Counseling

7.

Service provided by community pharmacist in guiding patients and

helping them locate appropriate health professionals is considered as:

Clinical Pharmacology

a)

A. Referral service

b)

B. Personalized patient care service

c)

C. Clinical service

d)

D. Consultant service

8.

Which of the following is an aspect of non-verbal communication

a)

A. Volume

b)

B. Tone

c)

C. Facial expression

d)

D. Language

9.

Administration of which drug in pregnancy is associated with

Phocomelia?

a)

A. Tetracycline

b)

B. Alcohol

c)

C. Thalidomide

d)

D. Phenytoin

10.

Which of these strategies will improve patient compliance?

a)

A. Multiple doses

b)

B. Inappropriate packing

c)

C. Complex therapeutic regimen

d)

D. Simple regimen (single dose)

11.

Increased CNS depressant observed when alcohol is combined with

sedatives is due to which of the following?

a)

A. Drugs having opposing pharmacological effects

b)

B. Drugs having similar pharmacological effects

c)

C. Idiosyncrasy

d)

D. Pharmacokinetic

12.

Which of the following medication is safe to use in the third trimester of

pregnancy?

a)

A. Acetaminophen

b)

B. Warfarin

c)

C. Aspirin

d)

D. Oxycodone

13.

Which of the following statement is true about Phase-II clinical trials?

a)

A. Large number of healthy volunteers are studied.

b)

B. Used to determine maximum tolerated dose

c)

C. Used to determine efficacy

d)

D. Used to determine toxicity

14.

Study to detect ADR, where group of patients with disease due to a drug is

compared with group who does not receive drug is:

a)

A. Disease oriented system

b)

B. Drug oriented system

c)

C. Complication oriented system

d)

D. Mixed system

15.

Reduced therapeutic activity of Diazepam, theophylline etc. in smokers is

due to which of these alterations?

a)

A. Alteration of absorption

b)

B. Alteration of distribution

c)

C. Alteration of metabolism

d)

D. Alteration of excretion.