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Bioenergetics & Thermodynamics

Total questions: 24

Worksheet time: 27mins

Name
Class
Date
1.

A reaction that is exergonic will be spontaneous. True or False?

(a)  

2.

An endergonic reaction requires an input of energy to proceed. True or False?

(a)  

3.

By definition, a spontaneous reaction is one in which

a)

energy is released

b)

energy is absorbed

c)

the energy change is zero

d)

the reaction is fast

e)

the reaction is slow

4.

Reactions that are thermodynamically unfavourable (energy consuming reactions) can occur in living cells because they can be coupled with reaction which have a negative ΔG\Delta G  . True or False?

a)

true

b)

false

5.

Which statement about ΔG\Delta G  is correct?

a)

a positive or negative ΔG tells us which direction the reaction will proceed

b)

ΔG depends on the concentration of reactants and products

c)

ΔG is affected by temperature

d)

ΔG is affected by pressure and pH

e)

ΔG is negative for endergonic reactions

6.

Which equation defines a system at equilibrium?

a)

ΔG > 0

b)

ΔG° = ΔG

c)

ΔG  = 0

d)

ΔG  = RT ln ([products]/[reactants])

7.

Consider these reactions:

ATP → ADP + Pi ΔG°' = −31 kJ/mol

glucose-6-phosphate → glucose + Pi ΔG°' =  −13 kJ/mol

glucose + ATP → glucose-6-phosphate + ADP ΔG°' = ?

What is the ΔG°' of the last reaction?

a)

-44 kJ/mol

b)

-18 kJ/mol

c)

+18 kJ/mol

d)

+44 kJ/mol

8.

If the  ∆G°' of the reaction A → B is -40 kJ/mol, under standard conditions the reaction ________

a)

is at equilibrium

b)

will never reach equilibrium

c)

will not occur spontaneously

d)

will proceed at a rapid rate

e)

will proceed spontaneously from left to right

9.

The reaction A + B → C has a ΔG0' of –20 kJ/mol at 25 °C.  

Starting under standard conditions, one can predict that ________

a)

at equilibrium, the concentration of B will exceed the concentration of A

b)

at equilibrium, the concentration of C will be less than the concentration of A

c)

at equilibrium, the concentration of C will be much greater than the concentration of A or B

d)

C will rapidly break down to A + B

e)

when A and B are mixed, the reaction will proceed rapidly toward formation of C

10.

A chemical reaction is faster when

a)

∆G > 0

b)

∆G < 0

c)

the activation energy is high

d)

the activation energy is low

11.

Oxidation refers to the

a)

loss of oxygen

b)

gain of oxygen

c)

loss of electrons

d)

gain of electrons

12.

An oxidising agent

a)

loses oxygen

b)

gains oxygen

c)

loses electrons

d)

gains electrons

13.

Biological oxidation-reduction reactions always involve ________

a)

transfer of electron(s)

b)

direct participation of oxygen

c)

mitochondria

d)

formation of water

e)

transfer of hydrogens

14.

In biological redox reactions, hydrogen ions are usually transferred along with electrons. True or false

a)

true

b)

false

15.

Standard reduction potential (E°) is measured in Volts in standard conditions, and relates with the affinity for electrons of an electron acceptor. True or False?

a)

true

b)

false

16.

Which of the following is not true about enzymes:

a)

they increase ∆G of reactions

b)

they are usually made of amino acids

c)

they lower the activation energy of chemical reactions

d)

each one is specific to the particular substrate(s) to which it binds

17.

Which of the following senetences about endergonic and exergonic reactions is false?

a)

endergonic reactions have a positive ΔG and exergonic reactions have a negative ΔG

b)

endergonic reactions consume energy and exergonic reactions release energy

c)

both endergonic and exergonic reactions require energy to overcome an activation barrier

d)

endergonic reactions take place slowly and exergonic reactions take place quickly

18.

Which of the following is the best way to judge the relative activation energies between two given chemical reactions?

a)

compare the ΔG values between the two reactions

b)

compare their reaction rates

c)

compare their ideal environmental conditions

d)

compare the spontaneity between the two reactions

19.

Which of the following is not true about enzymes:

a)

they increase ΔG of reactions

b)

they are usually made of amino acids

c)

they lower the activation energy of chemical reactions

d)

each one is specific to the substate(s) to which it binds

20.

If the ΔG0ΔG^{'0}   of the reaction A \rightarrow  B is 40 kJ/mol, under standard conditions the reaction:

a)

is at equilibrium

b)

will proceed spontaneously from left to right

c)

will proceed spontaneously from right to left

d)

will never reach equilibrium

e)

will proceed at a rapid rate

21.

For the reaction A → B, ΔG0ΔG^{'0}   = – 60 kJ/mol.

The reaction is started with 10 mmol of A; no B is initially present.

After 24 hours, analysis reveals the presence of 8 mmol of A and 2 mmol of B. Which option is the most likely explanation?

a)

A and B have reached equilibrium concentrations

b)

an enzyme has shifted the equilibrium toward A

c)

the formation of B is kinetically slow; equilibrium has not been reached by 24 hours

d)

formation of B is thermodynamically unfavourable

e)

the result described is impossible, given the fact that ΔG'0 is -60 kJ/mol

22.

Which of the following compounds releases the most free energy on hydrolysis?

phosphoenolpyruvate – 61.9 kJ/mol

1,3-bisphosphoglycerate – 49.4 kJ/mol

ATP (→ AMP) – 45.6 kJ/mol

Phosphocreatine – 43.1 kJ/mol

GTP (→ GDP) – 30.5 kJ/mol

a)

phosphoenolpyruvate

b)

1,3-bisphosphoglycerate

c)

ATP (→ AMP)

d)

Phosphocreatine

e)

GTP (→ GDP)

23.

Biological oxidation-reduction reactions always involve ________

a)

transfer of election(s)

b)

direct participation of oxygen

c)

mitochondria

d)

formation of water

e)

transfer of hydrogens

24.

Bioenergetics studies energy transformations. Muscle contractions involve the conversation of

a)

chemical energy to kinetic energy

b)

chemical energy to potential energy

c)

kinetic energy to chemical energy

d)

potential energy to chemical energy

e)

potential energy to kinetic energy