Pessaries are known to be

Bougies are known to be

When suppositories promote defecation and treat anorectal diseases it is said to have a?

When suppositories introduces drug into the body it is said to have a ?

A pediatric suppository can be which of the following?

The pH of the mucous layer in the rectum is 6.8-7.4, with ?

Which of the following statements are TRUE about Rectal Drug Absorption? Select all that apply

Which of the following are considered Physiological Factors affecting rectal drug absorption? Select all that apply

Which of the following are Physicochemical properties of APIs affecting rectal drug absorption? Select all that apply

Which of the following are Physicochemical properties of the base affecting rectal drug absorption? Select all that apply

Which of the following are limitations of rectal administration? Select all that apply

Suppositories for local action are mostly used to reduce pain and itching due to hemorrhoids.

Which of the following is an example of Suppositories for local action?

Which of the following is an example of Suppositories for systemic action?

Shape is an important characteristic of a vaginal insert and should be carefully designed.

Which of the following are TRUE about Shape & Size of Vaginal Inserts? Select all that apply

When Vaginal Delivery is Beneficial? Select all that apply

Preferential delivery to the uterus on vaginal is the first uterine pass effect.

Systemic drug absorption is unfavorable when a vaginal insert containing an antibiotic for the treatment of a vaginal infection is administered to a patient.

Which of the following are TRUE about Vaginal Drug Absorption? Select all that apply

Which of the following are examples for Vaginal Inserts for Systemic Action? Select all that apply

Which of the following drugs is a Contraceptive for termination of pregnancy from 12th to 20th gestational week?

Which of the following is beneficial for drugs subjected to extensive first-pass metabolism?

Which of the following are the commonly delivered drugs for treatment of vaginal disorders? Select all that apply

GENDER specific, is one of the limitations of Vaginal Administration/

Commonsense!

Which of the following ingredients is very important in the typical suppository composition?

The drug loading in a Typical Suppository Composition?

The BASE/VEHICLE (and protectant) in a Typical Suppository Composition?

Common sense

Understand this

Cocoa Butter (Theobroma Oil) is considered which type of base?

Which of the following are TRUE about Cocoa Butter (Theobroma Oil) ? Select all that apply

Due to polymorphism cocoa butter should not be melted at high temperature and chilled quickly. This leads to a metastable form (α) that has a lower melting temperature

Which form of cocoa butter has the highest melting point?

Which of the following is similar to cocoa butter, but show no polymorphism?

Which of the following bases do not melt at body temperature (melting point is above body temperature) , but slowly dissolve in body fluids and it is less frequently used?

Liquid at RT, clear, colorless

Semisolid, wax-like, white

Solid, wax-like, white (3350 & 8000)

Which of the following need to contain at least 20% water to prevent irritation?

Understand this

Which of the following is a water soluble base incorporating at least 20% water in the base causing irritation.

Which of the following is Not for Rectal Use , but suitable for vaginal inserts and is hygroscopic and thus can cause dehydration?

Hygroscopicity and Potential interactions with APIs are Disadvantages of Glycerinated Gelatin Base.

Which of the following are excipients agents decreasing Melting-point? Select all that apply

Which of the following are excipients agents increasing Melting-point? Select all that apply

Understand the choices based on solubility

Which of the following is the most common method for all kind of suppositories?

In fusion molding if necessary, lubricate mold with SMALL amount of mineral oil or glycerin.

Uses special suppository-making machine to compress paste-like mass into suppository and APIs insoluble in the base.

Which of the following applies to Packaging of Suppositories? Select all that apply

Which of the following statements is TRUE about Suppositories?

Which of the following is a Quality Assurance test that oversees for suppositories dosage forms?

Which of the following suppositories should be moistened with water before insertion? Select all that apply

Which of the following are TRUE statements about Patient Counseling in Suppositories? Select all that apply

If needed a suppositories can be cut in half.

The desired property of a base is the absorption of water.