WorksheetsPCC2 - Exam 3 - Mirza
Total questions: 22
Worksheet time: 11mins
You are compounding a gel. Which of the following would you select as a gelling agent?
magnesium stearate
petrolatum
sucrose
carbomer
Which physiochemical property of gels is exploited in the formulation of Milk of Magnesia (an oral laxative)?
imbibition
thixotropy
syneresis
swelling
Which of the following is false with reference to pharmaceutical creams?
creams are semi solid emulsions for external application
creams consist of at least two phases
creams do not require a preservative because of their high oil content
creams are used for their emollient properties
Which of the following semisolid preparations would not spread readily on the skin?
ointments
creams
pastes
lotions
Gel formation is a two-step process that involves hydration of a gelling agent followed by its gelation?
true
false
Which of the following shows the correct increasing order of the drug release potential of ointment bases?
emulsion bases<water-soluble bases<absorption bases<oleaginous bases
absorption bases<emulsion bases<oleaginous bases< water-soluble bases
water-soluble bases<emulsion bases<absorption bases<oleaginous bases
oleaginous bases<absorption bases<emulsion bases<water-soluble bases
Which of the following types of ointment bases is washable?
oleaginous base
o/w emulsion base
w/o emulsion base
Which of the following best describes the term “occlusive dressing”?
refers to an air and moisture impermeable barrier
refers to a semipermeable membrane
refers to a moisturizing film
A compounding pharmacist needs to incorporate a water-soluble API into an ointment base. The most appropriate way to process is
to disperse the drug in the ointment base
to dissolve the drug in a small volume of water
to dissolve the drug in the ointment base
Which of the following topical dosage form is most suitable for the treatment of oozing wounds?
an ointment
a cream
a paste
Which of the following is a compendial requirement for
hardness test
disintegration test
microbial content
peel adhesion test
Choose which of the following statements is false
synthetic polymers, natural gums, and clays are common gelling agents
two phase gels are thixotropic
a typical dispersion medium of oleogeis is water
Semi solid systems in which a liquid phase is constrained within a three-dimensional polymeric matrix are defined as
gels
creams
suppositories
ointments
plasters
Which of the following describes the mechanism of stabilization of emulsions by emulsifiers?
by reducing the interfacial tension between oil and aqueous phases
by increasing the interfacial tension between oil and aqueous phase
by increasing sedimentation rate of the internal phase
by decreasing the sedimentation rate of the internal phase
When compounding an emulsion that contains a flavoring agent, the flavoring agent should be added to
the continuous phase (external) phase
the disperse (internal) phase
the internal aqueous phase
the internal oil phase
the emulsifier
“Dry gum” method (also known as the 4:2:1 method) is often used to prepare emulsion formulations. According to this method, how much oil should be used to compound 140 ml of a primary emulsion
10 ml
20 ml
60 ml
40 ml
80 ml
Which of the following correctly describes the use of tween (polysorbate) in pharmaceutical formulations?
it is a surfactant
it is used as a thickening agent
its a non-aqueous solvent
As a pharmacy intern, you are asked to prepare an emulsion using the English gum method (also known as the wet gum method). What will be your very first step in preparing the emulsion?
Triturate the gum with water
triturate the gum with oil
thoroughly mix oil and water
combine oil, water, and gum altogether
According to Bancroft's rule, the phase in which an emulsion is less soluble constitutes a continuous phase.
true
false
Which of the following auxiliary labels one needs to use for an oral emulsion?
shake well before use
for oral use only
for external use only
A pharmacist is preparing an emulsion and wishes to choose the most lipophilic surface active agent he has in the pharmacy. Which of the following excipients would be the preferred option?
sorbitan monostearate (HLB=4.7)
Sorbitan tristearate (HLB=2.1)
Glyceryl monostearate (HLB=3.8)
POE sorbitan trioleate (HLB=11)
POE sorbitan stearate (HLB=13.1)
A pharmacist is preparing an emulsion and wishes to choose the most hydrophilic surface agent he has in the pharmacy. Which of the following excipients would be the preferred option?
sorbitan monostearate (HLB=4.7)
Sorbitan tristearate (HLB=2.1)
Glyceryl monostearate (HLB=3.8)
POE sorbitan trioleate (HLB=11)
POE sorbitan stearate (HLB=13.1)
