WorksheetsTherapy Refresher - Diabetes
Total questions: 24
Worksheet time: 12mins
After Digestion & Absorption of Glucose in Blood from Small Intestine ,glucose is utilized in -
Body cell
Blood
Liver
Adipose Tissues
After Digestion & Absorption glucose is stored as glycogen in -
Body Cell
Blood
Liver
Adipose Tissuesl
After Digestion & Absorption glucose is stored as fat in -
Body Cell
Blood
Liver
Adipose Tissues
Diabetes is defined as -
Metabolic disorder characterized by hypoglycemia due improper metabolism
Acute metabolic disorder characterized by persistent hyperglycemia due to insulin deficiency only
Acute metabolic disorder characterized by persistent hyperglycemia due to insulin resistance only
Chronic metabolic disorder characterized by persistent hyperglycemia due to insulin deficiency or insulin resistance or both
Gluconeogenesis is the Process of -
a. Formation of new Glucose from the Non-Carbohydrate Source (fats & Proteins) in Liver
b. Formation of new Glucose from Glycogen in Liver
Both a & b
None
INSULIN is secreted -
When glucose level is Higher than the Normal level in the blood
When glucose level is Lower than the Normal level in the blood
When glucose level is same as the Normal level in the blood
None
INSULIN is secreted from -
Beta cells of Liver
Beta cells of Pancreas
Alpha cells of Liver
Alpha cells of Pancreas
The Function of INSULIN, is to regulate the Blood Glucose Level by -
Digesting carbohydrate
Informing the body cells to allow the entry of Glucose inside the cells
Informing liver to convert Glycogen to Glucose & initiate Gluconeogenesis
All of the above
There are ______ of INSULIN Secretion.
1 phase
2 phases
3 phases
4 phases
GLUCAGON is secreted ________
When glucose level is Higher than the Normal level in the blood
When glucose level is Lower than the Normal level in the blood
When glucose level is same as the Normal level in the blood
Anytime
The Function of GLUCAGON, is to regulate the Blood Glucose Level by ____
Digesting carbohydrate
Informing the body cells to allow the entry of Glucose inside the cells
Informing liver to convert Glycogen to Glucose & initiate Gluconeogenesis
All of the above
Type 2 Diabetes Complications are ____
a. Macro-vascular
b. Micro-vascular
Both a & b
None
Macro-vascular Complications are _____
Retinopathy
Nephropathy
Coronary Artery Disease
Neuropathy
Micro-vascular Complications are _____
Stroke
Nephropathy
Coronary Artery Disease
Peripheral Vascular Disease
The Mode Of Action of Gliclazide
Increase Insulin Secretion from Beta cell of Pancreas by binding to SUR-2A receptors
Increase Insulin Secretion from Liver cells by stimulating liver cells
Increase the hepatic glucose output, by helping liver to become insulin sensitive
Increase Insulin Secretion from Beta cell of Pancreas by binding to SUR-1 receptors of beta cells in islets of Langerhans
The Mode Of Action of VILDAGLIPTIN
Decrease the effect of Both GLP-1 & GIP Hormone by inhibiting DPP-4 enzyme
Prolongs the effect Only GIP Hormone OR Only GLP-1 Hormone by inhibiting DPP-4 enzyme
InhibitsDecrease the effect of Only GIP Hormone OR Only GLP-1 Hormone by inhibiting DPP-4 enzyme DPP-4 Enzyme
Prolongs the effect of Both GLP-1 & GIP Hormone by inhibiting DPP-4 enzyme
GIP Hormone works on _____
Alpha Decreases Hepatic Glucose Output
Beta cells hence increases the secretion of Insulin
Alpha cells and decreases Glucagon breakdown
Beta cell and increases the Hepatic Glucose Output
GLP-1 Hormone works on ______
Only Alpha to decrease the secretion of Glucagon
Only Beta cells to Increase the secretion of Insulin
Both Alpha and Beta cells to decrease the secretion of Insulin and increase the secretion of Glucagon
Both Alpha and Beta cells to Increase the secretion of Insulin and decrease the secretion of Glucagon
Gliclazide is Cardio Safe as It selectively binds only to _____
SUR2A receptor on Beta cells of Pancreas
SUR-1 receptor on Heart
SUR-1 receptors of Pancreas
Both SUR-1 and SUR2A receptors of Heart and Beta cells of Pancreas
Gliclazide is Kidney Safe as ____
Active metabolites are formed & hence can be given to CKD stage 3,4 & Dialysis patients
NO Active metabolites are formed & can be given to CKD stage 3,4 & Dialysis patients
Moderately Nephro toxic
Both of the above
The MOA of Voglibose ____
Delays Glucose absorption from the Small Intestine by Inhibiting Alpha-Glycosidase Enzyme
Prolongs Glucose absorption from the Small Intestine by Inhibiting DPP-4 enzyme
Decreases Glucose absorption from the Small Intestine by stimulating Beta cells of Pancreas
Decreases Glucose absorption from the Small Intestine by Inhibiting Alpha-Glycosidase Enzyme
The MOA of Pioglitazone ____
Increase Insulin Resistance and Decrease Insulin Sensitivity and Decrease Glucose Uptake to the targeted cells of body
Increase Insulin Resistance and Increase Insulin Sensitivity and Decrease Glucose Uptake to the targeted cells of body
Decrease Insulin Resistance and Increase Insulin Sensitivity thus Increase Glucose Uptake to the targeted cells of the body
Decrease Insulin Resistance and Increase Insulin Sensitivity thus decreases the Glucose Uptake to the targeted cells of body
Pioglitazone acts by working on _____
PPAR-alpha of Liver/Pancreas
PPAR-Gamma of Liver/Pancreas
PPAR-alpha of Nucleus of the cells
PPAR-Gamma of Nucleus of cells
SGLT2 inhibitors also called gliflozins, are a class of medications which act by _____
Increasing reabsorption of glucose in the kidney thus increase blood sugar by stimulating sodium-glucose transport protein 2
Inhibiting reabsorption of glucose in the kidney but increase blood sugar by stimulating sodium-glucose transport protein 2
Inhibiting reabsorption of sodium in the kidney thus increase blood pressure by inhibiting sodium-glucose transport protein 2
Inhibiting reabsorption of glucose in the kidney thus lower blood sugar by inhibiting sodium-glucose transport protein 2
