WorksheetsNUR354 pharm II exam 2 review
Total questions: 75
Worksheet time: 4hrs 45mins
what are the 3 components of the CV system?
blood vessels
heart
blood
CSF
what is the criteria for normal BP? (please label the values)
(a)
what are the criteria to be diagnosed for HTN? SATA
SBP >130
DBP >80
2-3 visits to establish baseline
living sedentary lifestyle
this term is defined as the hardening of blood vessels
Arteriosclerosis
Atherosclerosis
Aneurysm
Hypertension
this term is defined as the buildup of plaque in the blood vessels
Arteriosclerosis
Atherosclerosis
Aneurysm
Hypertension
what term defined rupture of the blood vessels?
(a)
identify some non-pharmacological interventions for hypertension. SATA
quit smoking
increase caffeine intake
reduce alcohol
following a ADA diet
True or False. BP meds can be discontinued right away if the patient deems it not helpful to their BP.
true
false
Which of the ff statements are true regarding HTN medications? SATA
Most BP meds are NOT safe in pregnancy
Assess BP after administration
BP meds are RARELY given PRN
Many pts are only prescribed one BP med
what is the goal for BP treatment?
to immediately lower BP to reach a therapeutic level
to maintain good level for a long period
to reduce the risk of MI or stroke
to d/c therapy of other meds r/t HTN
RAAS (renin-angiotensin aldosterone system) is run by which organ system?
hepatic
renal
respiratory
cardiac
what is the main goal of the RAAS?
to lower BP
to bring up BP
to increase clotting
to prevent infection
this enzyme is released by the kidneys as a part of the renin-angiotensin aldosterone system.
renin
angiotensin I
angiotensin II
aldosterone
this chemical is released by the liver to help with increasing of BP within the RAAS?
renin
angiotensin I
angiotensin II
aldosterone
angiotensin II is a product of renin and angiotensin I.
what are the effects of angiotensin II in the body? SATA
release aldosterone
vasoconstriction
vasodilation
retains fluid in the body
which of the ff are the 1st line drug classes for the tx of HTN? SATA
ACE inhibitors (angiotensin converting enzyme)
ARB (angiotensin receptor blockers)
CCB (calcium-channel blockers)
thiazide diuretics
loop diuretics
which drug class prevents the conversion of angiotensin I into angiotensin II?
ACE inhibitors
ARBs
thiazides
CCB
ACE inhibitors can be given for HTN, cardiac disease, stroke prevention, and ________
renal diseases
heart failure
angina
dysrhythmias
what is an expected side effect of lisinopril?
cough
kidney injury
facial swelling
neutropenia
Losartan helps lower BP by?
preventing conversion of angio I into angio II
preventing angio II from plugging into its receptors
inhibiting Ca channel mov't in muscles
blocking renin from adding with angio I, making angio II
valsartan and losartan can be given for HTN and ______.
angina
renal disease
edema
heart failure
which of the ff meds are teratogenic (causes damage to fetus)? SATA
ACE inhibitors
ARB
renin blockers
aldosterone antagonists
there are 2 categories under Calcium Channel Blockers. Which of the two acts on the blood vessels ONLY.
dihydropyridine
non-dihydropyridine
what drugs are under Non-dihydropyridines CCB? SATA
amlodipine
nicardipine
verapamil
diltiazem
T or F. Dihydropyridine CCB are not 1st line drugs for HTN.
True
False
which drug class is often used as 1st line tx of HTN for African American population?
angiotensin converting enzyme inhibitors
angiotensin II receptor blockers
dihydropyridines CCB
nonhydropyridines CCB
which of the ff is an indication for Dihydropyridine CCB besides HTN?
angina
dysrhythmias
renal disease
stroke prevention
diuretics have different categories: loop, thiazides, _______, ADH, ___________, and carbonic anhydrase inhibitors. (SATA)
K+ sparing
(aldosterone antagonists)
Osmotic
Alpha 1 antagonists
hydralazine
this drug blocks renin from adding with angiotensin I (creating angiotensin II).
lisinopril
sodium nitroprusside
aliskirin
hydralazine
this class of diuretics is the most potent of all diuretics making it NOT 1st line for tx of HTN.
thiazide
K+ sparing
loop
osmotic
which drug class works at the nephron loop (loop of Henle) and blocks the body from reabsorbing Na and Cl followed by water?
carbonic anhydrase inihibitor
osmotic
aldosterone antagonists
loop
this drug at the distal convoluted tubule and blocks reabsorption of Na and Cl.
chlorthalidone
torsemide
spironolactone
losartan
this drug class blocks aldosterone at the collecting duct resulting in diuresis.
Carbonic anhydase inhibitor
Osmotic diuretic
ADH (antidiuretic hormone)
K+ sparing diuretics
which drug classes can cause hyperkalemia? SATA
K+ sparing
ARB
ACE
CCB
Osmotic diuretic drug Mannitol works by making blood hypertonic by pulling out fluid from the brain into the bloodstream. This results into a decrease of (a) in the brain?
(proper name or initials are accepted)
this drug is indicated for severe shock and cardiac arrest. It works by directly pulling water from filtrate and causes vasoconstriction.
spironolactone
antidiuretic hormone
HCTZ
bumex
what are the indications for acetazolamide?
glaucoma
ALS
AMS
stroke
this drug works by directly dilating the arteries and is indicated as an alternative agent for HTN.
aliskirin
isosorbide dinitrate
hydralazine
sodium nitroprusside
this is an emergency medication given to dilate arteries and veins. this medication can metabolize into thiocyanate (cyanide).
sodium nitroprusside
doxazosin
clonidine
bidil
what is the name of combo drug of Hydralazine + Isosorbide Dinitrate?
(a)
this drug is indicated for HTN and BPH.
prazosin
clonidine
isosorbide dinitrate
nicardipine
this drug is mainly used for HTN but has other off label uses. it works by increasing alpha 2 resulting in vasodilation.
metoprolol
clonidine
hydralazine
nipride
what is a CAM for UTI prevention?
(a)
name 1 of the primary labs done to check for kidney function
(proper name or initials are accepted)
(a)
what is the difference between AKI and CKD?
what should you include in your patient education regarding diuretics? SATA
expect increased urine output
take it in the morning
placing a catheter in while on diuretics is necessary
these drugs have an AE of dehydration
T or F. it is a requirement to adjust nephrology medication (i.e., diuretics) dosages to be adjusted based on kidney function.
true
false
Identify three classes of medications that are nephrotoxic?
aminoglycoside
APAP
ACE inihibitors
Loop diuretics
what does refractory mean?
unresponsive to
responsive to
can cause rebound symptom
is not working
Give one biggest risk factor for cardiac disease (Life Simple 7)?
(a)
What is the pathway of cell death? (SATA)
ischemia
infarction
injury
infection
what is a common cause of MI?
arteriosclerosis
atherosclerosis
aneurysm
PAD
stable angina or unstable angina.
This occurs when the blood vessels are in bad shape which leads to ischemia. This does not persist after treatment of nitroglycerin.
stable angina
unstable angina
What diagnoses makes up acute coronary syndrome (ACS)? SATA
stable angina
unstable angina
non- ST elevation MI
ST elevation MI
Unstable angina is when chest pain continues to persist even after the administration of nitroglycerin.
true
false
this treatment is also called angioplasty. This requires the patient to go to the cath lab where a wire will be inserted in the femoral artery to the heart to find the clot.
(proper name or initials)
(a)
which of the ff patient populations usually suffer with torturous vessels? SATA
DM
HTN
HLD
PVD
Which of the ff is the treatment for a myocardial infarction with torturous vessels?
percutaneous intervention
coronary artery bypass graft
closed-heart surgery
stenting
this medication is the 1st line tx for acute angina.
propranolol
nitroglycerin
ranolazine
morphine
Which classes of drugs nitroglycerin falls under? SATA
direct vasodilator
nitrate
calcium channel block
Beta-adrenergic receptor antagonist
Identify the side effects of Nitroglycerin. (SATA)
headache
hypotension
reflex tachycardia
tachypnea
Which of the following routes for nitro is used as a backup agent for the prevention of angina?
SL
TD
IV
PO
Identify the correct dosage of nitroglycerin.
0.1 mg
4000 mcg
0.4 mg
1 mcg
Nitroglycerin can be given up to 4 times, 3 mins apart.
true
false
what are the 2 contraindications for nitro? SATA
cannot be given within 48-72 hours of an ED med
cannot be given for right ventricular MI
cannot be given for a pt in shock
cannot be given for a patient taking anticoagulants
beta-blockers are used as an alternative for prevention of angina.
true
false
The indications for beta adrenergic receptor antagonists are anxiety, angina, dysrhythmias, acute MI, hypertension, and (a) .
(proper name or initials)
Before administering these meds, a nurse must check the patients BP and HR.
amlodipine
labetalol
verapamil
torsemide
administration of beta-blockers should be considered in which population of patients? (SATA)
COPD
DM
HTN
asthma
There are no BP meds safe to be administered for pregnant women.
true
false
which medication has an adverse effect of QT prolongation. it works by decreasing the O2 demand in the heart.
aspirin
alteplase
diltiazem
ranolazine
which of the 2 CCB is used for angina prevention?
non-dihydropyridines
dihydropyridines
these medications are used first for patient having a myocardial infarction. SATA
alteplase
morphine
oxygen
aspirin
Alteplase falls under this drug class. It has a MOA of going to the clot and breaking it up. (proper name only!)
(w/ or w/o S accepted)
(a)
what is a proper treatment/intervention for a hypertensive emergency, asymptomatic with BP of 200/100?
none
give nitroglycerin
give ACE inhibitors
give clonidine or hydralazine
