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WorksheetsCVS Pharmacology II
Total questions: 6
Worksheet time: 4mins
Nitrates that cause RAPID relief of angina
when administered correctly, undergo first-pass effect.
rapidly reaches therapeutic concentration.
cause venodilation.
cause orthostatic hypotension.
cause bradycardia.
A newly diagnosed hypertensive patient has a history of vasospastic angina.
Which of the following drugs or drug classes would be the most rational for starting antihypertensive therapy because it exerts antihypertensive effects, directly lowers myocardial oxygen demand and consumption, and also tends to inhibit cellular processes that otherwise favour coronary vasospasm?
Angiotensin-converting enzyme (ACE) inhibitor or angiotensin receptor
blocker
Alpha-adrenergic blocker
Nifedipine
Thiazide diuretic
Verapamil
A doctor considers prescribing propranolol for a 53-year-old patient.
Which of the following preexisting conditions (comorbidities) would most
likely contraindicate the safe use of this drug?
Stable angina
Asthma
Essential hypertension
Mild heart failure
Sinus tachychardia
We treat a patient with a drug that affects the clotting-thrombolytic
systems for a time sufficient to let the drug’s effects and blood levels stabilize at a therapeutic level. We then isolate platelets from this patient's blood sample and test their in vitro aggregatory responses to adenosine diphosphate (ADP), collagen, PAF, and thromboxane A2. Aggregatory responses to ADP are inhibited; responses to the other platelet proaggregatory agonists are unaffected.
Which drug did we most likely administer to this patient?
Aspirin
Streptokinase
Clopidogrel
Heparin
Warfarin
Quinidine is prescribed to a patient with recurrent atrial fibrillation.
Which of the following is the BEST statement about the beneficial effect of quinidine in this patient?
It increases blood pressure via a direct vasoconstrictor effect.
It is contraindicated if the patient also requires anticoagulant therapy.
It delays atrial depolarization.
It slows electrical impulse conduction velocity.
It will increase cardiac contractility (positive inotropic effect) independent of its antiarrhythmic effects.
Simvastatin
increases the absorption of cholesterol from the intestine.
inhibits HMG-CoA reductase.
causes a decrease in the number of LDL receptors in the liver.
causes myositis and rhabdomyolysis in 50% of patients.
treatment requires monitoring of liver function.
