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GTB225 Study design

Total questions: 18

Worksheet time: 11mins

Name
Class
Date
1.

Researcher controls study variables

a)

Observational study

b)

Experimental study

2.

Descriptive study

a)

Observational study

b)

Experimental study

3.

A clinician investigated his patients with severe cough to find relationship between smoking and bloody phlegm. He asked his patients about their smoking behaviour. Then, he assembled the data in a table. This can be which type of epidemiological design?

a)

Case control

b)

Cohort (Retrospective)

c)

Cohort (Prospective)

d)

Randomized controlled trial

4.

Which of the following designs is/are suitable for studying a genetic polymorphism in relation to risk of diabetes mellitus? (> 1 correct answer)

a)

Case

control study

b)

Cross

sectional study

c)

Cohort study

d)

Randomized controlled trial

5.

Researcher measures and records what is happening without manipulating variables

a)

Experimental study

b)

Observational study

6.

NOT examine relationship between exposure and effect

a)

Descriptive study

b)

Analytical study

c)

Observational study

7.

Prevalence study

a)

cohort

b)

cross-sectional

c)

case-control

d)

community trial

8.

NOT investigate causal relationship (> 1 correct answer)

a)

cross sectional

b)

cohort

c)

descriptive

d)

case-control

9.

Retrospective study

a)

cross sectional

b)

cohort

c)

case control

10.

To test a new vaccine

a)

cohort

b)

case control

c)

field trial

d)

randomized controlled trial

11.

To evaluate health education program (>1 correct answer)

a)

randomized controlled trial

b)

field trial

c)

community trial

d)

clinical trial

12.

NOT longitudinal study

a)

prospective study

b)

retrospective study

c)

case control

d)

cross sectional

13.

Cohort study (>1 correct answer)

a)

prevalence study

b)

incidence study

c)

experimental study

d)

follow-up study

14.

To investigate cause factor of a rare disease

a)

field trial

b)

case-control

c)

community trial

d)

cohort

15.

The

Cancer and Steroid Hormone (CASH) study, in which women with breast cancer and a

comparable group of women without breast cancer were asked about their prior use of oral

contraceptives is an example of which type(s) of study? (>1 correct answer)

a)

clinical trial

b)

cohort study

c)

cohort study

d)

case

control study

e)

observational study

16.

When studying diet and risk of chronic diseases, a cohort study generally has the following

advantage compared to a case

control study: (> 1 correct answer)

a)

Potential confounders can be taken into account

b)

Recall bias does not occur

c)

Various dietary exposures can be studied at the same time

d)

Fewer subjects are needed

17.

A pharmaceutical company showed the following in an article: "1500 subjects with a cold were

treated with our new medicine. Within three days, 95% were asymptomatic and

this result was

statistically significant." The company claims the new medicine was effective.

Is this conclusion justified?

a)

Yes, because the effect was very large (95% of the subjects benefitted from treatment).

b)

No, because statistical significance indicates that the null hypothesis ("no effect") was correct.

c)

No, because no control group was involved in the study.

d)

Yes, because the effect of treatment could not be explained by chance.

18.

500 women aged 40 –54 who present for routine check-ups are asked about their meat consumption. 20% of the women turn out to be vegetarian. During the 5 year follow-up period, 5 vegetarians and 43 non-vegetarians develop colorectal cancer. Which of the following best describes the study design?

a)

Cohort study

b)

Case-control study

c)

Cross-sectional study

d)

Randomized controlled study