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Nucleic Acids and DNA Replication

Total questions: 30

Worksheet time: 21mins

Name
Class
Date
1.

Genes contain instructions for assembling

a)

operons

b)

chromatin

c)

protein

d)

mutagens

2.

Which type of RNA functions as a blueprint of the genetic code?

a)

mRNA

b)

rRNA

c)

tRNA

d)

RNA Polymerase

3.

The hereditary information in DNA is encoded in the sequence of

a)

nitrogen bases

b)

hydrogen bonds

c)

sugars

d)

phosphate groups

4.

The amino acids are actually carried by the rRNA.

a)

This statement is True.

b)

This statement is False - change the underlined word to mRNA.

c)

This statement is False - change the underlined word to tRNA.

d)

This statement is False - change the underlined word to DNA.

5.

The Figure shows the % of bases in a DNA sample. How much Thymine should you expect to find in the sample?

a)

44%

b)

28%

c)

24%

d)

22%

6.

During DNA replication, a DNA strand that has the bases CTAGGT produces a complementary strand with the bases

a)

GAUCCA

b)

AGCTTG

c)

GATCCA

d)

TCGAAC

7.

Who was credited for discovering the structure of DNA?

a)

Franklin and Wilkins

b)

Hershey and Chase

c)

Franklin and Griffith

d)

Watson and Crick

8.

What does the figure show?

a)

anticodons

b)

exons

c)

introns

d)

the genetic code

9.

In eukaryotes, DNA

a)

is circular.

b)

is located in the ribosomes.

c)

floats freely in the cytoplasm.

d)

is located in the nucleus.

10.
In a strand of DNA, if it contains 20% of Thymine, then how much Guanine would be present?
a)
30%
b)
20%
c)
80%
d)
10%
11.
Which 2 molecules form the sides (backbone) of the DNA ladder?
a)

ribose sugar and phosphate

b)
deoxyribose sugar and a hydrogen bond
c)

deoxyribose sugar and the bases

d)
deoxyribose sugar and phosphate
12.
A process in which DNA has the unique ability to make an exact copy of itself.
a)
Replication
b)
Translation
c)
Transcription
d)

Gene splicing

13.
Nitrogenous bases are joined by which type of bond?
a)
polar bonds
b)
ionic bonds
c)
covalent bonds
d)
hydrogen bonds
14.
What is the correct complimentary strand for the following DNA?ATCGAG
a)
TACGAG
b)
ATCGAG
c)
TAGCTG
d)
TAGCTC
15.
What is the difference between DNA and RNA in terms of bases?
a)
RNA contains uracil in place of thymine
b)
RNA contains uracil in place of adenine
c)
RNA contains uracil in place of guanine
d)
RNA contains uracil in place of  cytosine
16.
Which enzyme has the job of unzipping the double helix?
a)
Helicase
b)
Polymerase
c)
Ligase
d)
Primerase
17.
Which enzyme fixes the Okazaki fragments in the lagging strand?
a)
Helicase
b)
Polymerase
c)
Ligase
d)
Primerase
18.
This picture is illustrating the ____ nature of DNA.
a)
anti-parallel
b)
deoxyribosic
c)
helical
d)
radioactive
19.
Polymerase is able to replicate the new DNA ______ along the leading strand.
a)
continuously
b)
only in short fragments
c)
very slowly
d)
prokaryotically
20.
DNA replication turns one strand of DNA into two new strands of DNA. What percent of each new strand is the old strand?
a)
Half of each new DNA is the old DNA
b)
The old strand of DNA was digested, so none
c)
The new DNA is entirely made up of the old DNA
d)
About every sixth base comes from the old DNA
21.
Sometimes, DNA is called "semi-conservative." Why might this be?
a)
The old strand is "conserved" and used to make the new strands
b)
Uracil is "conserved" in that it is only used to make the new strands
c)
ATP is "conserved" via the usage of facilitated diffusion
d)
Ligase is "conserved" in that it is denatured by the process
22.
Which of the following must happen first in order for DNA replication to occur?
a)
DNA polymerase binds to the leading strand
b)
DNA is unwound
c)
Hydrogen bonds form between bases
d)
chromosomes condense
23.
Okazaki fragments form on the:
a)
lagging strand
b)
leading strand
c)
base-pairs
d)
5' end
24.

Which enzyme is responsible for adding nucleotides to the free three prime end

a)

Helicase

b)

Topoisomerase

c)

DNA Polymersase 3

d)

DNA Polymersase 1

25.

The separation of the two single strands of DNA creates a ‘Y’ shape?

a)

enzyme

b)

unzip

c)

replication fork

d)

strand

26.

Structure C is

a)

helicase

b)

primase

c)

DNA polymerase III

d)

gyrase

27.

#5

a)

Leading strand

b)

Lagging Strand

c)

Replication fork

d)

Helicase

28.

Which of the following explains the base pairing rules?

a)

G pairs with T with 3 hydrogen bonds and A pairs with C with 2 hydrogen bonds

b)

G pairs with T with 2 hydrogen bonds and A pairs with C with 3 hydrogen bonds

c)

A pairs with T with 2 hydrogen bonds and G pairs with C with 3 hydrogen bonds

d)

A pairs with T with 3 hydrogen bonds and G pairs with C with 2 hydrogen bonds

29.

Which of the following describes how DNA replication differs between a prokaryotes and eukaryotes?

a)

Prokaryotes have circular DNA requiring one origin of replication while eukaryotes have multiple origins on linear DNA

b)

Prokaryotes have linear DNA requiring one origin of replication while eukaryotes have multiple origins on circular DNA

c)

Prokaryotes have circular DNA requiring multiple origins of replication while eukaryotes have one origin on linear DNA

d)

Prokaryotes have linear DNA requiring multiple origins of replication while eukaryotes have one origin on circular DNA

30.

What is the difference between leading and lagging strands?

a)

DNA is synthesized in a 5' to 3' direction on the lagging strand and a 3' to 5' direction on the leading strand

b)

DNA is synthesized in a 3' to 5' direction on the lagging strand and a 5' to 3' direction on the leading strand

c)

DNA is synthesized continuously on the leading strand and discontinuously on the lagging strand

d)

DNA is synthesized discontinuously on the leading strand and continuously on the lagging strand

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