WorksheetsNeurodegenerative Diseases
Total questions: 15
Worksheet time: 8mins
One of the treatment approaches in Alzheimer's disease is the enhancement of cholinergic function.
True
False
Which of the following symptoms would lead to a diagnosis of parkinson's disease:
Tremor
Rigidity
Postural instability
All of the above
What causes parkinson's?
Sensory neuron death
Motor neurones apathy
Decreased acetylcholine
Loss of dopamine producing cells
The leading treatment for Parkinson's disease is
Carbidopa-levodopa
Cardipoda-levopoda
Carbinova-levopada
Carbonipa-levadopa
Which of the following is a symptom of parkinson's disease
Fast speaking
Hyper activity
Bradykinesia (slow movement)
Changes to levels of _____ and _____ have key roles in parkinson's disease
Dopamine, acetylcholine
Serotonin, acetylcholine
Dopamine, melatonin
Dopamin, serotonin
The two characteristic pathologies of Alzheimer's disease are...
Lewy bodies and neurofibrillary tangles
Amyloid plaques and neurofibrillary tangles
Ubiquitinated inclusions and amyloid plaques
Amyloid plaques and lewy bodies
Which protein is most commonly associated with neurofibrillary tangles?
Tau
Actin
APP
β-secretase
Below is/ are the symptom(s) of Alzheimer’s Disease EXCEPT:
Short-term memory loss
Change in mood & personality
Lethargy (lack of energy)
All of the above
Alzheimer’s Disease is the result of damage to the brain that affects the activity of the neurotransmitter ___________.
dopamine
serotonin
adrenaline
acetylcholine
The anatomical hallmarks of Alzheimer's disease are beta-amyloid plaques and neurofibrillary tangles.
True
False
In Parkinson's disease, the levels of dopamine and acetylcholine are evenly balanced.
True
False
The following drug (for Alzheimer's disease) and its primary mechanism is TRUE:
Donepezil - AChE-I (selective & reversible)
Rivastigmine - AChE-I (selective & reversible)
Galantamine - AChE-I (pseudo-irreversible)
None the above
NMDA antagonist regulates excessive glutamate in patient with Alzheimer's disease
True
False
The drugs used in Parkinson's disease are Levodopa, •COMT inhibitors •MAO-B inhibitors, •Dopamine agonists, Amantadine and •Anticholinergics.
True
False
