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Enzymes that Manipulate DNA

Total questions: 16

Worksheet time: 11mins

Name
Class
Date
1.
What is the purpose  of an enzyme?
a)
give permission for the reaction
b)
raise activation energy
c)
speed up reactions
d)
control how many reactions occur
2.
What happens when enzymes are heated to a high temperature?
a)
The enzymes die.
b)
The shapes of the enzyme are altered or denatured
c)
The enzymes' amino acid sequence changes.
d)
The enzymes remain the same
3.

1. The DNA base sequences recognized by Endonuclease are called

a)

a).Restriction Site

b)

b). Recognition Site

c)

c).Fragmentation Site

d)

d).cutting Site

4.

The recognition sites for restriction enzymes are :

a)

a).Tautomer

b)

b). Pallindrome

c)

c).Metamere

d)

d).Acronym

5.

Restriction Enzymes are isolated from :

a)

a).Protozoa

b)

b). Bacteria

c)

c).Virus

d)

d).Fungi

6.

Restriction Enzymes were primarily used as :

a)

a).Defence by Protozoa against antibiotics

b)

b).Tool by Virus to cleave Bacterial genome

c)

c)Defence by Bacteria against bacteriophages viruses

d)

d).All of the above

7.

In molecular cloning, a __________ is used to insert a fragment of DNA into the host cell.

a)

plasmid

b)

DNA fragment

c)

bacterium

d)

virus

8.

The enzyme used to join the DNA fragments

a)

Topoisomerase

b)

DNA ligase

c)

DNA polymerase

d)

Reverse transcriptase

9.

Which of the following tools of recombinant DNA technology is INCORRECTLY paired with one of its uses?

a)

restriction endonuclease - production of DNA fragments for gene cloning.

b)

DNA ligase - enzyme that cuts DNA, creating sticky ends.

c)

reverse transcriptase - production of cDNA from mRNA.

d)

Taq polymerase - copies DNA sequences in the polymerase chain reaction.

10.
Which is true about plasmids?
a)
Plasmids can be cut at specific sequences called restriction sites.
b)
Plasmids contain a promoter sequence that defines where transcription begins.
c)
Plasmids can contain an antibiotic resistance gene.
d)
All of the statements are true about plasmids.
11.
In bacteria, restriction enzymes are used for defense. They cut up the DNA of a virus that infects bacteria.
a)
True
b)
False
12.

Which of the following terms describes the process of the uptake of recombinant plasmids into bacteria cells?

a)

amplification

b)

insertion

c)

transformation

d)

screening

13.

Which enzyme helps fuse the foreign into the new DNA?

a)

DNA Polymerase

b)

DNA ligase

14.

To produce desired protein _____________ should be taken from any source like human, animal and plant.

a)

recombinant DNA

b)

Target DNA

c)

plasmid

d)

ligase

15.

Which of the following enzymes can cut nucleic acids?

a)

DNA polymerase

b)

restriction endonuclease

c)

modifying enzymes

d)

reverse transcriptase

16.

What type of cut is this photo?

a)

Blunt

b)

sticky