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Pediatric Toxicology

Total questions: 10

Worksheet time: 8mins

Name
Class
Date
1.

The most benefit from activated charcoal occurs within _ hour(s) from ingestion

a)

1

b)

4

c)

6

d)

24

2.

Which antidote is used to restore hepatic glutathione (GSH) stores in acetaminophen toxicity?

a)

Activated charcoal

b)

N-Acetylcysteine (NAC)

c)

Sodium bicarbonate

d)

Succimer

3.

Which of the following is NOT true regarding treatment with N-Acetylcysteine?

a)

IV formulation is preferred over oral

b)

The 3-bag method is associated with less anaphylaxis

c)

The nomogram is used for single ingestions within 4-24 h

d)

Nausea/vomiting is more likely with oral administration

4.

Which drug is used to alkalize the urine and promote aspirin elimination by the kidneys?

a)

Sodium bicarbonate

b)

Activated charcoal

c)

Succimer

d)

Fomepizole

5.

Treatment for aspirin toxicity may be discontinued when serum salicylate concentration is < _ mg/dL

a)

30

b)

60

c)

90

d)

120

6.

_ is used in severe lead toxicity to chelate heavy metals and promote urinary excretion

a)

Succimer

b)

Fomepizole

c)

Naloxone

d)

Deferoxamine

7.

The only effective long-term treatment for lead toxicity is _

a)

Chronic succimer usage

b)

Identify and remove source

c)

Urinary alkalization

d)

Hemodialysis

8.

An osmolar gap >10 mOsm/kg is used to screen for toxic ingestion of _

a)

Acetaminophen

b)

Opioids

c)

Alcohols

d)

Lead

9.

Which antidotes can be used to competitively inhibit alcohol dehydrogenase in methanol and ethylene glycol toxicity (select all that apply)

a)

Ethanol

b)

Fomepizole

c)

Activated charcoal

d)

Folic Acid

10.

By competitively inhibiting alcohol dehydrogenase, fomepizole _ the formation of toxic metabolites.

a)

decreases

b)

increases

c)

has no effect

d)

completely stops