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WorksheetsIMMUNOLOGY
Total questions: 21
Worksheet time: 7mins
Antinuclear antibody tests are performed to help diagnose:
acute leukemia
acute leukemia
lupus erythematosus
Crohn disease
In the anti-double-stranded DNA procedure, the antigen most commonly utilized is:
rat stomach tissue
Crithidia luciliae
mouse kidney tissue
Toxoplasma gondii
Which of the following is most useful in establishing a diagnosis in the convalescence phase of a viral infection?
Slide culture
Shell vial
Serological techniques
Culture on McCoy media
The presence of HbsAg, anti-HBc and often HbeAG is characteristic of:
early acute phase HBV hepatitis
Recovery phase of acute HBV hepatitis
early convalescent phase HBV hepatitis
Past HBV infection
AN example of an organ specific disease with autoimmune antibodies is:
Wegener granulomatosus
Hashimoto thyroiditis
Rheumatoid arthritis
Systemic lupus erythematosus
IgM antibodies are frequently hemolytic because of:
their dimeric structure
their sedimentation coefficient of 7-15 S
the molecule's 5 antigen binding sites
their efficient ability to fix complement
To which of the following classes do the antibodies that cause hemolytic disease of the newborn belong
IgA
IgG
IgE
IgD
Which of the following releases histamine and other mediators from basophils?
C3a
Clq
properdin factor B
C4
A monoclonal spike of IgG, Bence Jones proteinuria, and bone pain are usually associated with:
Burkitt lymphoma
Severe combined immunodeficiency disease
Bruton disease
Multiple myeloma
Which of the following is the most common humoral immune deficiency disease?
Bruton agammaglobulinemia
Selective IgA deficiency
IgG deficiency
Wiskott-Aldrich syndrome
Immunodeficiency with thrombocytopenia and eczema is often referred to as:
DiGeorge syndrome
Ataxia talengiectasia
Bruton agammaglobulinema
Wiskott-Aldrich syndrome
The autosomal recessive form of severe combined immunodeficiency disease is also referred to as:
Bruton agammaglobulinemia
DiGeorge syndrome
Swiss-type lymphopenic agammaglobulinemia
Wiskott-Aldrich syndrome
Hereditary angioedema is characterized by:
decreased activity if C3
increased activity of C1 esterase inhibitor
decreased activity of C1 esterase inhibitor
decreased activity if C2
Infantile X-linked agammaglobulinemia is referred to as:
Bruton agammaglobulinemia
DiGeorge syndrome
Swiss-type agammaglobulinemia
Hypogammaglobulinemia
Which of the following is used to detect allergen specific IgE?
RIST
IEP
RAST
CRP
In skin test, a wheal and flare development is indicative of:
Immediate hypersensitivity
antibody mediated cytotoxicity
immune complex
delayed hypersensitivity
T cells are incapable of:
collaborating with B cells in antibody responses
secretion of immunoglobulins
secretion of cytokines
Producing positive skin tests
Which T-cell malignancy may retain "helper" activity with regard to immunoglobulin synthesis by B cells?
Hodgkin lymphoma
Acute lymphocytic leukemia (ALL)
Sézary syndrome
Chronic lymphocytic leukemia (CLL)
Cells from a patient with hairy cell leukemia have immunologic and functional features of:
mast cells and B lymphocytes
B lymphocytes and T lymphocytes
Granulocytes and monocytes
B lymphocytes and monocytes
HLA-B8 antigen has been associated with which of the following pairs of diseases?
ankylosing spondylitis and myasthenia gravis
celiac disease and ankylosing spondylitis
myasthenia gravis and celiac disease
Reiter disease and multiple sclerosis
Which of the following is an important marker for the presence of immature B cells in patients with acute lymphocytic leukemia (ALL)?
terminal deoxynucleotidyl transferase
adenosine deaminase
glucose-6-phosphate dehydrogenase
purine nucleoside phosphorylase
