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BDS Biochem 2

Total questions: 20

Worksheet time: 15mins

Name
Class
Date
1.

Classes of enzymes

a)

6

b)

4

c)

3

d)

8

2.

Isozyme forms of lactate dehydrogenase are

a)

3

b)

6

c)

5

d)

9

3.

Which of the following is a marker enzyme of myocardial infarction

a)

Creatine kinase CK2

b)

Lactate dehydrogenase LDH5

c)

Hexokinase

d)

Glucose 6 PO4 dehydrogenase

4.

Which of the following is a non-competitive enzyme inhibitor

a)

Allopurinol

b)

Malonate

c)

Iodoacetate

d)

Methotrexate

5.

Allopurinol is

a)

a non competitive enzyme inhibitor

b)

a competitive enzyme inhibitor

c)

used to treat Gout disease

d)

used to treat hyperuremia

6.

Induced fit model for enzyme action was proposed by

a)

Fisher

b)

Michaelis Menten

c)

Koshland

d)

Singer

7.

Gout is a disease marked by increased level of

a)

Urea

b)

Uric acid

c)

Creatinine

d)

Creatine

8.

End product of purine catabolism is

a)

Urea

b)

Uric acid

c)

Creatinine

d)

Hippuric acid

9.

Km value is

a)

Enzyme concentration at half of the maximum velocity of the reaction

b)

Substrate concentration at half of the maximum velocity of the reaction

c)

Inhibitor concentration at half of the maximum velocity of the reaction

d)

Co- enzyme concentration at half of the maximum velocity of the reaction

10.

The influence by substrate concentration factor on enzyme activity yields which type of curve?

a)

Sigmoidal

b)

Hyperbolic

c)

Parabolic

d)

Ellipsoidal

11.

Which enzyme catalyses the conversion of fructose 6 PO4 to fructose 1,6 bisphosphate?

a)

Phosphofructokinase 2

b)

Aldolase

c)

Hexokinase

d)

None of the above

12.

Which of the following substances is an inhibitor of the enzyme succinate dehydrogenase?

a)

Arsenite

b)

Fluoride

c)

Malonate

d)

None of the above

13.

The typical curve of an Allosteric enzyme is

a)

Parabolic curve

b)

S curve

c)

Sigmoidal curve

d)

Hyperbolic curve

14.

Which of the following is a positive allosteric modulator of hexokinase enzyme?

a)

ATP

b)

ADP

c)

Glucose 6 PO4

d)

Fructose 6 PO4

15.

Inactive pyruvate dehydrogenase complex becomes active when

a)

Phosphorylated

b)

Dephosphorylated

c)

Diphosphorylated

d)

Bisphosphorylated

16.

The hormone which induces the synthesis of pyruvate kinase in glycolysis pathway is

a)

Glucagon

b)

Thyroxine

c)

Insulin

d)

Growth hormone

17.

The normal activity range of aspartate transaminase in serum is

a)

Upto 20 IU/dL

b)

Upto 40 IU/dL

c)

Upto 40 IU/L

d)

Upto 20 IU/L

18.

Alkaline phosphatase is the marker enzyme of

a)

Hemolytic jaundice

b)

Obstructive jaundice

c)

Latent jaundice

d)

Rickets

19.

Which of the following enzymes is the marker of alcohol abuse?

a)

Lactate dehydrogenase (LDH - 5)

b)

Creatine kinase (CK -3)

c)

Lactate dehydrogenase (LDH - 4)

d)

Gama glutamyl transferase

20.

Which of the following enzymes is used in lysing intravascular clot?

a)

Papain

b)

Urokinase

c)

Streptokinase

d)

Asparaginase