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pharmacology of respi

Total questions: 54

Worksheet time: 49mins

Name
Class
Date
1.

H1 blockers or H1 antagonist

(a)  

2.

Suppressing adrenal medulla stimulation, autonomic

gandia stimulation, and exocrine gland secretion, such as

lacrimal and salivary secretions.

(a)  

3.

Inhibiting most smooth muscle responses to histamine in

particular, blocking the constriction of bronchial, GI, and

vascular smooth muscle.

(a)  

4.

The most common adverse reaction of antihistamine

(a)  

5.

adverse reaction of antihistamine, cns reaction

a)

dizziness and fatigue

b)

disturbed coordination

c)

muscle weakness

d)

tachycardia

6.

The most common adverse reaction of antihistamine is cns depression with

the exception of what antihistamines?

a)

fexofenadine

b)

loratadine

c)

desloratadine

d)

formoterol

7.

Act as an inflammatory agent in cases of severe

anaphylaxis, allergic reaction where there is

bronchoconstriction

(a)  

8.

Used to treat hematologic conditions such as rheumatoid

arthritis , lupus, inflammation of the blood vessels

(a)  

9.

Used as adjuvant therapy incases of premature birth

(a)  

10.

steroids are given on what hour prior to expected delivery of preterm infant

(a)  

11.

is administered to accelerate

infant slung maturation /development stimulates synthesis

and release of surfactant

(a)  

12.

when can steroids be given?

(a)  

13.

Premature newborns are given what steroids to help maintain normal bp ?

a)

hydrocortisone

b)

dexamethasone

c)

theophylline

d)

bethametasone

14.

Methylxanthine derivatives:

a)

aminophylline

b)

theophylline

c)

terbutaline sulfate

d)

albuterol

15.

Bronchial Smooth Muscle Relaxants

a)

aminophylline

b)

theophylline

c)

terbutaline sulfate

d)

dexamethasone

16.

Used to treat acute exacerbation of asthma Increase

bronchodilation, increasing vital capacity

(a)  

17.

side effect of bronchodilators :

a)

tachycardia

b)

easy fatigability

c)

muscle weakness

d)

dizziness

18.

Used for the treatment of symptoms associated with

asthma and chronic obstructive pulmonary disease

(COPD).

(a)  

19.

Short-acting beta2-adrenergic agonists include:

a)

Albuterol , Bitolterol

b)

Levalbuterol, Metaproterenol

c)

Pirbuterol, Terbutaline

d)

Formoterol,

Salmeterol

20.

Long-acting beta2-adrenergic agonists include:

a)

Albuterol

b)

Formoterol

c)

Salmeterol

d)

Pirbuterol

21.

Adverse reaction to short-acting beta2-adrenergic agonists

include?

a)

paradoxical bronchospasm

b)

tachycardia

(palpitations)

c)

tremors, dry mouth

d)

bronchospasm

22.

Adverse reaction to long-acting beta2-adrenergic agonists

include

a)

bronchospasm

b)

tachycardia, palpitation

c)

hypertension, and tremors

d)

dry mouth

23.

Loosens bronchial secretions hence eliminated by

coughing

(a)  

24.

Facilitates removal of viscous mucus

(a)  

25.

reduces thickness and

adhesiveness, and surface tension of mucus for

easier clearing up of airways. Provides a

soothing effect to mucus membranes of the

respiratory tract resulting in a more productive

cough.

(a)  

26.

guaifenesin is taken with?

(a)  

27.

examples of experctorants/mucolytics?

a)

guaifenesin

b)

carbocisteine

c)

dypenhydramine

d)

salmeterol

28.

ADVERSE REACTION TO GUAIFENESIN

a)

Vomiting, Diarrhea, Drowsiness

b)

Nausea, Abdominal pain, Headache

c)

hives

d)

easy fatigability

29.

● Interferes with the biosynthesis of the bacterial cell wall

● May also inhibit bacterial enzymes and cellular

metabolism

(a)  

30.

● May also inhibit protein synthesis

(a)  

31.

suppress or inhibit coughing. Typically

used to treat dry, nonproductive coughs.

(a)  

32.

anesthetizes stretch receptors

throughout the bronchi and alveoli which stops

the coughing.

(a)  

33.

in administering benzonatate orally, why swallow instead chew?

a)

cause its bitter

b)

causes local anetsthetic effect in mouth

c)

causes mouth sores

d)

cause it is more easy to swallow than to chew

34.

suppresses cough reflex by direct action on the

cough center in the medulla of the brain thus

lowering the cough threshold

a)

codeine

b)

Dextromethorphan hydrobromide

c)

benzonatate

d)

Hydrocodone bitrate

35.

antitussives drugs

a)

Hydrocodone bitrate

b)

Codeine, Dextromethorphan hydrobromide

c)

Benzonatate

d)

cephalosporin

36.

- Used for treatment of allergies

- Can be used for prevention of asthma especially for

pediatrics

(a)  

37.

Drug of choice for individuals with exercise- induced

asthma

(a)  

38.

these agents seem to inhibit the release

of inflammatory mediators by stabilizing the mast cell

membrane, possibly through the inhibition of chloride

channels.

(a)  

39.

ADVERSE REACTION TO INHALED MAST CELL STABILIZER

a)

● Pharyngeal and tracheal irritation

b)

● Cough

● Wheezing

● Bronchospasm

c)

● Headache

d)

● Hives or skin rash

40.

mast cell stabilizer medications

a)

Nedocromil

b)

cromolyn sodium

c)

benzonatate

d)

codeine

41.

are used for the prevention and

long-term control of mild asthma.

(a)  

42.

are substances which are released from the

mast cells.

(a)  

43.

can result in smooth muscle contraction of the airways and

increase and activates secretion of other inflammatory

mediators

a)

eosinophils

b)

basophils

c)

immune response

d)

neutrophils

44.

Inhibit leukotriene from

interacting with its receptor so

there is a blocking action

(a)  

45.

Include Zafirlukast and

Montelukast

(a)  

46.

Inhibits production of

lipoxygenase, an enzyme that

produces leukotrienes which

contributes to swelling,

bronchoconstriction and

mucus secretion.

(a)  

47.

Include Zileuton

(a)  

48.

Adverse reaction to leukotriene modifier include:

a)

○ Headache

○ Dizziness

b)

○ Nausea and vomiting

c)

○ Myalgia

○ Cough

d)

● Hives or skin rash

49.

Zileuton is contraindicated in patients with?

(a)  

50.

are medicines that relieve congestion by

reducing swelling, inflammation and mucus formation

within the nasal passages or the eye.

(a)  

51.

Used to help reduce the symptoms of a blocked or stuffy

nose

(a)  

52.

stimulates SNS to reduce swelling of

respiratory tract

(a)  

53.

provides immediate relief from nasal

congestion

(a)  

54.

Most adverse reactions of decongestants result from CNS

stimulation and include:

a)

Restlessness and insomnia

b)

Nausea, Palpitations and tachycardia

c)

Difficulty urination, Elevated blood pressure

d)

myalgia