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Cell Biology

Total questions: 187

Worksheet time: 2hrs 9mins

Name
Class
Date
1.

cells are...

a)

Complex factories that carry out functions of life, most basic unit of all living things  

b)

located between plasma membrane and the nucleus 

c)

specialized structures that preform specific functions 

d)

super large

2.

Plasma Membrane(Cell Membrane): forms the (a)   boundary of the cell, where the cell interreacts with external environment 

3.

Nucleus: located (a)   of the cell and directs cell activities 

4.

T or F? Cytoplasm is located between plasma membrane and the nucleus 

a)

True

b)

False

5.

specialized structures that preform specific functions 

 

a)

organisms

b)

organelles

c)

cells

6.

lipid bilayer is composed of...

a)

phospholipids and cholesteryl

b)

proteins

c)

amino acids

7.

which organelle

- functions as the outer boundary of the cell

- controls the entry and exit of substances

- functions in intercellular communication

- enable cells to recognize one another 

a)

golgi apparatus

b)

lysosomes

c)

plasma membrane

d)

mitochondria

8.

chromatin: dispersed, thin strands of (a)   and associated proteins

9.

T or F? the nucleolus acts as the control center of the cell

a)

True

b)

False

10.

Cell (a)   and energy use:  

- Involves all chemical reactions that occur within a cell

11.

Many metabolic reactions have energy released through (a)   which helps maintain body temp 

12.

(a)   of molecules: 

- Different cells of the body synthesize various types of molecules (proteins, nucleic acids, lipids) 

- Structural and functional characteristics of cells are determined by the types of molecules they produce 

13.

Cells communicate through chemical and energy signals 

a)

synthesis

b)

chemical reaction

c)

reproduction

d)

communication

14.

(a)   and inheritance: 

- Most cells contain DNA molecules of an individual 

- DNA determines the structural and functional characteristics of the cell 

-Inheritance is the transmission of traits from one generation to the next through gametes 

15.

T or F? cells have the same genetic code even after cell division 

(a)  

16.

what equipment do we use to see cells?

a)

camera

b)

microscope

c)

magnifying glass

d)

x ray

17.

_____ microscopes(light is used to produce an image): regularly used to examine biopsy specimens 

________ microscopes(beams of electrons are used to produce an image): used to see objects that are much smaller than a cell 

(a)  

18.

T or F? The cytoplasm of a cell is different from the extracellular environment 

(a)  

19.

(a)   potential: an electrical charge difference across the plasma membrane which is a result of a cell's regulation of ion movement into and out of the cell 

20.

More ________ ion along the outside of the plasma membrane while there are more __________ charged ion and proteins along the inside the plasma membrane 

(a)  

21.

The plasma membrane consists primarily of ______ and _______ (45-50%) with a very small amount of _____________ (4-8%) 

a)

lipids

proteins

carbohydrates

b)

proteins

lipids

carbohydrates

c)

carbohydrates

proteins

lipids

d)

lipids

proteins

amino acids

22.

Carbohydrates + lipids =

a)

glycoproteins

b)

glycolipids

23.

the collection of glycolipids and glycoproteins is called... 

 

(a)  

24.

There are two predominant lipids of the plasma membrane: _____________ and ___________

(a)  

25.

Phospholipids readily assemble to form a lipid bilayer(double layer of phospholipid molecules) since they have a _____ head and a ________ tail 

(a)  

26.

These polar heads are attracted to water molecules making they (a)   (water-loving) heads which are exposed to the extracellular fluid in the cytoplasm of the cell (both are aqueous solutions) 

27.

The nonpolar tails are not attracted to water molecules making them (a)   (water-fearing) which face each other in the interior of the plasma membrane 

28.

receptor associates with the G protein complex, what step is this in the

a)

1

b)

2

c)

3

d)

4

e)

5

29.

A ligand is a (a)  

30.

Selectively permeable means ______

a)

only some substances can pass through

b)

only some substances can pass through

31.

Diffusion, active transport and endocytosis are all mechanisms for ______

a)

copying genetic information

b)

making ATP

c)

moving substances across the membrane

d)

catalyzing enzymatic reactions

32.

When a lipid soluble molecule encounters the lipid bilayer, ______

a)

the substance can pass through the membrane if there is an appropriate channel for it

b)

it dissolves into the membrane

c)

it is repelled by the membrane

33.

T or F? Active transport does not requires ATP

(a)  

34.

Activated G protein complexes make changes (a)   a cell

35.

Large, non-lipid-soluble molecules and small pieces of matter are transported across the cell membrane by...

a)

vesicles

b)

transport proteins

c)

channels

36.

Endocytosis is an example of

a)

passive transport

b)

active transport

c)

vesicular transport

37.

Movement of material into or out of a cell using a vesicle and ATP

(a)  

38.

Movement of substances from areas of lower to higher concentration with the use of an ATP-powered pump.

(a)  

39.

Movement of a substance from areas of lower to higher concentration along with an ion that moves from an area of higher to lower concentration. 

(a)  

40.

Identify the passive transport mechanism that requires a carrier protein that exhibits specificity, saturation and competition

(a)  

41.

Oxygen levels in inhaled air in the lungs is much higher than oxygen levels in the capillary blood. Capillary blood has a much higher concentration of carbon dioxide than air in the lungs. Predict what will happen?

a)

Oxygen will diffuse out of the capillaries.

b)

Oxygen will diffuse into the capillaries.

42.

Identify the types of substances that require vesicles for transport across the cell membrane - select all that apply

a)

Small pieces of matter

b)

Large molecules

c)

Non-lipid soluble molecules

d)

Phospholipids and cholesterol

43.

T or F? A concentration gradient occurs when the solute are not evenly distributed in a solvent

a)

True

b)

False

44.

How does passive transport compare to active transport with regard to energy expenditure?

a)

Passive transport uses energy to transport large, charged molecules. Active transport only carriers small molecule

b)

Passive transport always acts as a symport and uses ATP.

c)

Passive transport does not require ATP; active transport does.

d)

Both active and passive transport require ADP.

45.

Molecules can pass through the plasma membrane by (a)  

46.

What effect does increasing the temperature of a solution have on its solutes?

a)

Increasing temperature has no effect on diffusion since both solvent and solute molecules are heated at the same time

b)

Increasing temperature decreases diffusion

c)

Increasing temperature increases diffusion of solutes

47.

The sugar concentration in your glass of ice tea is very high at the bottom and low at the top. This concentration distribution is an example of a

a)

facilitated diffusion

b)

facilitated diffusion

c)

osmotic equilibrium

d)

concentration gradient

48.

T or F? A fluid with a low viscosity flows more easily than a fluid with high viscosity

a)

True

b)

False

49.

ATP is necessary for ______ transport, but not necessary for ______ transport

a)

active, passive

b)

passive, active

50.

The diffusion of water across a semi-permeable membrane

(a)  

51.

Diffusion, active transport and endocytosis are all mechanisms for

a)

catalyzing enzymatic reactions

b)

moving substances across the membrane

c)

copying genetic information

d)

making ATP

52.

Membrane channel proteins called aquaporins are specialized for the passage of (a)   molecules

53.

Diffusion rate will increase as the size of the molecule (a)  

54.

The force required to prevent water from moving across a cell membrane is called ______ pressure

a)

osmotic

b)

hydrostatic

c)

gravitational

55.

Diffusion occurs more ______ in viscous solvents than in watery solvent

a)

slowly

b)

quickly

56.

If two solutions of differing concentrations of solute are separated by a semi-permeable membrane, the solution with the lower concentration solute and the higher concentration of solvent is referred to as being

(a)  

57.

Channels of membrane proteins specialized for the passage of water are called

a)

carrier proteins

b)

ligand-gated channels

c)

aquaporins

58.

Solutions with the same osmotic pressures are

(a)  

59.

What is osmotic pressure

a)

The response of enzymes to ATP

b)

The force expended by the G protein complex when a receptor has been activated

c)

The force exerted by the nucleoplasm during DNA transcription

d)

The force needed to keep water from moving by osmosis across a selectively permeable membrane

60.

A cell will ______ when placed into a hypertonic solution

a)

swell

b)

shrink

61.

The measurement of a fluid's resistance to flow is referred to as its

(a)  

62.

If the concentration of a solute is greater than the concentration of the intracellular environment of a cell, the solution is

a)

hyposmotic

b)

hypotonic

c)

hyperosmotic

d)

isosmotic

63.

As the concentration gradient of a diffusing substance decreases, the rate of diffusion (a)  

64.

What is mediated transport

a)

The movement of vesicles by intermediate filaments

b)

The process of peptide synthesis on the surface of the ribosome

c)

The movement of molecules across a membrane by means of a protein carrier.

d)

Movement of proteins through the cisterns of the endoplasmic reticulum

65.

A cell is placed in a hypertonic solution. This causes the cell to ______

a)

gain water

b)

lose water

66.

T or F? A fluid with a low viscosity flows more easily than a fluid with high viscosity

a)

true

b)

false

67.

Amino acids ______ enter the cell by directly diffusing through the plasma membrane

a)

can

b)

cannot

68.

T or F: Like diffusion, active transport only moves substances along their concentration gradient

a)

true

b)

false

69.

Large molecules move across cell membrane with the help or assistance of protein carriers. This type of transport is generically called

(a)  

70.

The movement of sodium and glucose from the lumen of the intestine into epithelial cells is an example of (a)   active transport

71.

The sodium-potassium pump is an example of ______ transport

a)

active

b)

passive

72.

The type of endocytosis that engulfs water in small vesicles is called

a)

pinocytosis

b)

phagocytosis

73.

Pinocytosis and phagocytosis are both forms of (a)  

74.

Receptor-mediated endocytosis is ______

a)

specific

b)

non specific

75.

How do pinocytosis and phagocytosis differ?

a)

Pinocytosis involves small soluble molecules and small vesicles while phagocytosis involves larger solid particles.

b)

Phagocytosis requires the expenditure of ATP, pinocytosis does not.

c)

ll cells perform pinocytosis, but only red blood cells can do phagocytosis.

d)

Phagocytosis involves small soluble molecules and small vesicles while pinocytosis involves larger solid particles.

76.

What is receptor-mediated endocytosis?

a)

A form of facilitated diffusion that requires ATP and a channel protein.

b)

The movement of molecules out of a cell packaged in a vesicle.

c)

the movement of molecules out of a cell packaged in a vesicle.

d)

A form of endocytosis triggered when a molecule binds to a specific membrane receptor.

77.

Which is a function of the cytoskeleton?

a)

Storing ribosomes

b)

Production of ATP

c)

Packaging of proteins into vesicles

d)

Movement of cell organelles

78.

The secretion of digestive enzymes by the cells of the pancreas and mucus by the cells of the salivary glands are examples of

a)

endocytosis

b)

exocytosis

c)

osmosis

d)

facilitated transport

79.

Which component of the cytoskeleton produces the internal scaffolding of the cell, is involved in cell division and is a component of the centrioles and spindle fibers?

a)

Intermediate filaments

b)

Microtubules

c)

Microfilaments

80.

The cellular material outside the nucleus but inside the plasma membrane that contains the organelles and cytosol is called

(a)  

81.

What is cytosol?

Multiple choice question.

a)

The fluid portion of the cytoplasm containing the cytoskeleton

b)

The fluid portion of the cytoplasm containing the organelles

c)

The fluid matrix found within the nuclear membrane

82.

Cytoskeletal filaments that are about 10 nm in diameter and provide mechanical strength to a cell are (a)   filaments

83.

Aggregates of chemicals either produced by or taken in by the cell (such as lipid droplets, glycogen granules, and pigments) are classified as ______

a)

inclusions

b)

organelles

c)

vesicles

84.

T or F: All organelles are surrounded by a membrane

(a)  

85.

In order for a cell to change its shape, which of the following must occur?

a)

Phospholipids must be removed from the membrane.

b)

Actin filaments must be broken down and reconstructed.

c)

New membrane-associated proteins must be manufactured.

d)

The plasma membrane must be broken down and rebuilt.

86.

What supports the extensions of nerve cells?

(a)  

87.

What is a cytoplasmic inclusion?

a)

Chemicals, minerals and other compounds produced in or stored in the cytoplasm

b)

An organelle necessary for cell functioning

c)

A ribosome or any other sub-microscopic organelle

d)

Waste products that are isolated in one area of the cell awaiting vesicular transport out of the cell

88.

A chromosome is a complex of ___ and _______

(a)  

89.

How does RNA leave the nucleus?

a)

nuclear pore

b)

exocytosis

c)

endocytosis

90.

The function of intermediate filaments is to ______

a)

provide mechanical strength to cells

b)

define the shape of the cell

c)

aid is cell division

91.

Melanin is considered a(n) ______

a)

organelle

b)

part of the cytoskeleton

c)

microtubule

d)

cytoplasmic inclusion

92.

During most of a cell's life, when it is not dividing, its DNA and associated proteins is(are) called

a)

messenger RNA

b)

histones

c)

chromatin

d)

glycogen

93.

A region of the nucleus that contains the DNA from which ribosomes are produced

(a)  

94.

What is the difference between DNA and RNA?

(2 correct answers)

a)

RNA carries information from the cytoplasm to the nucleus

b)

DNA resides solely in the nucleus

c)

DNA resides in the cytoplasm

d)

RNA carries information from nucleus to the cytoplasm

95.

Ribosomes are free or bound to the (a)  

96.

a nucleus ______ a surrounding membrane?

a)

has

b)

lacks

97.

How does RNA leave the nucleus?

a)

nuclear pores

b)

exocytosis

c)

diffusion

98.

ribosomes synthesis (a)  

99.

DNA is the cell's master set of instructions and is stored in the ______; RNA, however, carries information into the______

a)

nucleus, cytoplasm

b)

nucleus, nucleolus

c)

cytoplasm, nucleus

d)

nucleolus, nucleus

100.

cells must be able to (a)  

101.

The type of endoplasmic reticulum that lacks ribosomes, synthesizes steroids and other lipids, as well as detoxifying alcohol and other drugs is called (a)   endoplasmic reticulum

102.

What is the term used to describe a small generic membrane-bound structure that transports substances to the plasma membrane for release by exocytosis?

a)

Proteosome granule

b)

Secretory vesicle

c)

Centrosome

d)

Chromatid

103.

Ribosomes make.....

a)

proteins

b)

lipids

c)

cholesterol

d)

carbohydrates

104.

The membrane-bounded organelle containing a mixture of enzymes that function in digesting foreign matter, pathogens, and expired organelles is a __________

a)

ribosome

b)

peroxisome

c)

lysosome

105.

sugars stick to.....

a)

proteins/lipids

b)

ribosomes

106.

Organs like the liver and kidney cells contain cells that are active in detoxification. These cells contain a large number of ______

a)

peroxisomes

b)

lysosomes

c)

endoplasmic reticulum

107.

Which organelle is responsible for modifying and packaging newly synthesized proteins?

(a)  

108.

PROteasomes break down ______

a)

carbohydrates

b)

proteins

c)

lipids

d)

bacteria

109.

Secretory vesicles pinch off the ______

a)

golgi apparatus

b)

smooth ER

c)

nucleus

110.

The organelles in the cell that are specialized for synthesizing ATP are called

a)

mitochondria

b)

ribosomes

c)

lysosomes

111.

intercellular communication is (a)   cells

112.

The inner mitochondrial membrane usually has folds called ______ that project into the interior of the organelle

a)

cristae

b)

matrix

113.

You are a histologist studying muscle tissue biopsied from a student volunteers. One volunteer was an amateur athlete who actively engages in intramural sports for about 15 hours a week. The other volunteer was less athletic and spends only about an hour a week in athletic activities. Which of these volunteers would have the most mitochondria per muscle cell?

a)

The muscle cells in the student that participates in regular exercise has an increased energy demand and an increased number of mitochondria

b)

The muscle cells in the less athletic student would have more mitochondria but they would be smaller

114.

The barrel-like protein complexes found within the cytoplasm that break down and recycle other proteins within the cell are referred to as ______

a)

ribosomes

b)

microvilli

c)

intermediate filaments

d)

proteasomes

115.

A small cylindrical organelle composed of microtubules

(a)  

116.

Energy, in the form of ATP, is produced primarily in the cell's (a)  

117.

The region around the nucleus where the microtubules form is called the ______

a)

interphase

b)

centrosome

c)

nucleolus

d)

mitochondrion

118.

Microtubules that extend from the centrosome and attach to the chromosomes

(a)  

119.

Cilia line the respiratory and the ______ tract. 

a)

digestive

b)

female repro

c)

lymphatic

d)

urinary

120.

The only cells in humans with flagella are (a)   cells

121.

Two centrioles make up one...

a)

microtubule

b)

centrosome

c)

chromosome

d)

lysosome

122.

Pinocytosis = cell (a)  

Hint: pinot grigio

123.

Extensions of the plasma membrane that serve primarily to increase a cell's surface area are called

a)

microvilli

b)

cilia

c)

flagella

d)

microtubules

124.

The whiplike tail of a sperm is called a

(a)  

125.

The transmission of genetic characteristics from parent to offspring is called

a)

gene expression

b)

heredity

c)

mutations

126.

Transcription is the process of copying genetic instructions from ______

a)

DNA to tRNA

b)

tRNA to mRNA

c)

mRNA to tRNA

d)

DNA to mRNA

127.

During transcription, the enzyme ______ synthesizes molecules of RNA complementary to the DNA sequence

a)

ligase

b)

DNA polymerase

c)

helicase

d)

RNA polymerase

128.

Regions of the mRNA that do not code for any protein are called (a)  

129.

The production of proteins from information stored in DNA is called (a)   expression

130.

RNA polymerase is essential for synthesis of ______ from _____

a)

RNA, DNA

b)

DNA, RNA

c)

DNA, DNA

d)

RNA, RNA

131.

Pre-mRNA ______ exons

a)

contains

b)

does not contain

132.

Regions of the mRNA that code for proteins are called (a)  

133.

A three-base sequence in mRNA is called a

(a)  

134.

Transcription is the process of copying genetic instructions from ________

a)

DNA to mRNA

b)

mRNA to tRNA

c)

mRNA to DNA

d)

DNA to tRNA

135.

Which is a start codon?

a)

AUG

b)

GAG

c)

TAT

136.

Pre-mRNA is messenger RNA that is composed of ______

a)

introns and exons

b)

exons only

c)

introns but not exons

137.

Conversion of a nucleotide sequences in mRNA into a sequence of amino acids is known as ______

a)

translation

b)

replication

c)

transcription

138.

T or F: The codon AUG not only codes for the amino acid methionine, but also serves as a stop codon

a)

true

b)

false

139.

The form of mRNA that contains both introns and exons is called

a)

neo-mRNA

b)

pre-mRNA

c)

nascent mRNA

140.

At one end of each tRNA, there is a sequence of three nucleotides known as the (a)  

141.

How many base sequences are in one anticodon?

a)

1

b)

2

c)

3

d)

4

142.

The modification of protein after synthesis to produce a functional protein or active enzyme

(a)  

143.

The DNA coding for hemoglobin is expressed in ______  cells

a)

only red blood

b)

all 

c)

most

144.

One mRNA can have 10 or 20 ribosomes attached to it. This complex is called a (a)  

145.

What is the cell life cycle?

a)

The changes that occur in the cell from the time it forms until it produces 2 new cells

b)

The cell cycle describes the transcription of DNA and the production of protein

c)

Prophase, metaphase and anaphase are the stages of the cell cycle

d)

Events that occur in the cell after it forms until it dies

146.

What occurs during the G2 phase of the cell cycle?

a)

A cell leaves the cell cycle and ceases to divide

b)

The cell carries out routine metabolic activities. DNA is replicated in preparation for cell division to occur

c)

A cell synthesizes enzymes that control cell division as well as checks and repairs the newly copied DNA; both prepare the cell to divide

d)

The nucleus divides

147.

A cell makes a duplicate copy of its centrioles and all of its nuclear DNA during ______ phase of the cell cycle.

a)

S

b)

M

c)

anaphase

d)

telophase

148.

In the G0 phase, cells cease to divide

a)

true

b)

false

149.

The cell prepares for cell division during which gap phase?

a)

one

b)

two

150.

What does the cell make during the S phase?

a)

DNA

b)

RNA

c)

organelles

151.

Cells that leave the cell cycle and cease to divide for days or years are said to be in the Blank______ phase

a)

G0

b)

G2

c)

S

d)

M

152.

Name the phase of the cell cycle that runs from the end of cytokinesis to the beginning of the next prophase

(a)  

153.

What occurs during the G2 phase of the cell cycle?

a)

The cell carries out routine metabolic activities. DNA is replicated in preparation for cell division to occur

b)

A cell synthesizes enzymes that control cell division as well as checks and repairs the newly copied DNA; both prepare the cell to divide

c)

The nucleus divides

d)

A cell leaves the cell cycle and ceases to divide

154.

In DNA replication ______

a)

a shorter version of DNA is made

b)

an exact copy of DNA is made

155.

What is the function of the DNA polymerase?

a)

It splices DNA fragments

b)

It splices RNA fragments

c)

It catalyzes synthesis of new RNA strands

d)

It catalyzes production of new DNA strands

156.

During the synthesis (S) phase of the cell cycle a cell

a)

makes a duplicate copy of its centrioles and all of its nuclear DNA

b)

synthesizes enzymes that control cell division as well as checks and repairs the newly copied DNA

c)

leaves the cell cycle and ceases to divide

d)

forms two nuclei

157.

DNA ligase works on the ______ strand of DNA.

a)

leading

b)

lagging

158.

What are the two major events of cell division?

a)

Synthesis and meiosis

b)

Translation and transcription

c)

Mitosis and cytokinesis

159.

DNA (a)   splices Okazaki fragments together during DNA replication

160.

DNA polymerase makes the leading strand of DNA Blank______

a)

longer

b)

shorter

161.

The kinetochore is a ______ structure.

a)

lipid

b)

monosaccharide

c)

DNA

d)

protein

162.

A cell replicates its DNA then divides to form two daughter cells each of which contains one copy of the newly generated DNA

(a)  

163.

Mitosis is the division of ______

a)

cells nucleus

b)

cells cytoplasm

164.

What is the name of a protein associated with chromosomes that allows for the attachment of microtubules?

a)

Leading strand

b)

Kinetochore

c)

Actin

d)

DNA lingase

165.

True or false: The DNA of the daughter cells contains a new strand of the cell's DNA and a strand from the parent cell

a)

true

b)

false

166.

chromatids are (a)   copies

167.

The first sign of cytokinesis is a ______

a)

kinetochore

b)

centriole

c)

spindle appratus

d)

cleavage furrow

168.

Programmed cell death is ______

a)

meiosis

b)

cytokinesis

c)

apoptosis

d)

mitosis

169.

Cytokinesis is the division of the cell's ______ to form two cells

a)

cytoplasm

b)

cell

c)

membrane

d)

cytoplasms

170.

During (a)   chromosomes align along midline of cell

171.

One hypothesis on aging suggests that what type of genes are turned on late in life causing cells to deteriorate?

a)

Mitochondrial genes

b)

Death genes

c)

Cellular clock genes

d)

Radical genes

172.

Apoptosis is a(n) ______ process

a)

normal

b)

abnormal

173.

One of the major sources of DNA damage is (a)   , which are atoms or molecules with unpaired electrons

174.

mRNA stands for (a)  

175.

endo

a)

in

b)

out

176.

exo

a)

in

b)

out

177.

plasma membrane is (a)   permeable

178.

isotonic

a)

cell swells

b)

cell shrinks

c)

neither swell or shrink

179.

hypotonic

a)

swell

b)

shrink

c)

neither swell or shrink

180.

hypertonic

a)

swell

b)

shrink

c)

neither swell or shrink

181.

mediated transport process carried out by carrier/channel proteins; no ATP required

(a)  

182.

facilitated diffusion

a)

Amino acids and glucose in, manufactured proteins out

b)

proteins in, manufactured amino acids and glucose out

183.

Name this step of facilitated diffusion:

A glucose molecule enters a carrier protein from the extracellular fluid

The glucose binds to the carrier protein

a)

1

b)

2

c)

3

d)

4

184.

Name this step in facilitated diffusion:

The carrier protein changes shape and releases the glucose molecule into the cell

The carrier protein then resumes its original shape to transport additional glucose molecules

a)

1

b)

2

c)

3

d)

4

185.

T or F? active diffusion requires ATP

(a)  

186.

active transport concentration gradient

a)

low to high

b)

high to low

187.

T or F: the sodium potassium pump is an example of

a)

active transport

b)

diffusion

c)

osmosis