Which of the following adverse effects is commonly associated with the use of centrally acting sympatholytic agents?

he loop diuretics have their principal diuretic effect on the:

A patient has been diagnosed with uncomplicated primary hypertension. Of the choices below, what type of drug or combination of drugs would be preferable?

A 45-year-old man was just started on therapy for hypertension and developed a persistent, dry cough. Which is most likely responsible for this side effect?

Which may cause reflex tachycardia and/or postural hypotension on initial administration?

A 58-year-old female reports that she recently stopped taking her blood pressure medications because of swelling in her feet that began shortly after she started treatment. Which is most likely to cause peripheral edema?

A 70-year-old retired businessman is admitted with a history of recurrent heart failure and metabolic derangements. He has marked peripheral edema and metabolic alkalosis. Which of the following drugs is most appropriate for the treatment of his edema?

A 70-year-old woman is admitted to the emergency department because of a “fainting spell” at home. She appears to have suffered no trauma from her fall, but her BP is 120/60 when lying down and 60/20 when she sits up. Neurologic examination and an ECG are within normal limits when she is lying down. Questioning reveals that she has recently started taking “water pills” (diuretics) for a heart condition. Which of the following drugs is the most likely cause of her fainting spell?

Which arrhythmia can be treated with lidocaine?

A 60-year-old woman had a myocardial infarction. Which of the following should be used to prevent life-threatening arrhythmias that can occur post– myocardial infarction in this patient?

Which of the following drugs slows conduction through the AV node and has its primary action directly on L-type calcium channels?

A 36-year-old woman with a history of poorly controlled thyrotoxicosis has recurrent episodes of tachycardia with severe shortness of breath. When she is admitted to the emergency department with one of these episodes, which of the following drugs would be most suitable?

What makes losartan different from other ARBs?

How is spironolactone beneficial in HF?

Which one of the following is a significant unwanted effect of the drug named?

A 73-year-old man with a history of a recent change in his treatment for moderately severe HTN is brought to the emergency department because of a fall at home. Which is most likely to cause postural hypoTN and thus an inc risk of falls?

A 32-year-old woman with HTN wishes to become pregnant. Her physician informs her that she will have to switch to another anti-HTN drug. Which of the following drugs is absolutely contraindicated in pregnancy?

Which class of agents is recommended by the JNC-8 as first-line therapy for uncomplicated essential hypertension?

Potential side effects of the thiazide diuretics include:

Spironolactone:

Inhibit NaCl reabsorption by blocking the NaCl transporter

Blocks the uptake and the storage of biogenic amines = depletion of NE, DOPA, SE both central and peripheral neurons

Blocks the uptake and the storage of biogenic amines = depletion of NE, DOPA, SE both central and peripheral neurons

Which side effect is associated with amlodipine?

A 72-year-old woman has long-standing heart failure. Which one of the following drugs has been shown to reduce mortality in chronic heart failure