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Worksheets

Diabetes Pt. 1

Total questions: 17

Worksheet time: 12mins

Name
Class
Date
1.

Which of the following occurs in the Islets of Langerhans?

a)

gluconeogenesis

b)

secretion of somatostatin

c)

GLP-1 synthesis

d)

uptake of glucose into α cells via GLUT-1 transporter

2.

The majority of pancreatic cells are the α, β, δ, and ε islet cells.

a)

True

b)

False

3.

Insulin inhibits which of the following?

a)

glucagon

secretion

b)

somatostatin secretion

c)

hydrolysis of triglycerides in adipose cells

d)

gluconeogenesis

4.

Somatostatin inhibits which of the following?

a)

insulin secretion

b)

glucagon secretion

c)

growth hormone (GH) secretion

d)

thyroid-stimulating hormone (TSH)

5.

Which of the following stimulate glucagon release?

a)

insulin

b)

electric impulses from the vagus nerve

c)

epinephrine

d)

somatostatin

6.

Glucagon stimulates which of the following?

a)

alpha cells in the pancreas (more glucagon secretion)

b)

gluconeogenesis in the liver

c)

HSL in adipose tissue (freeing of FFAs)

d)

glycogenolysis in the liver

7.

Glucagon and GLP-1 are just different sections of the same protein chain called proglucagon.

a)

True

b)

False

8.

The α and β cells in the Islets of Langerhans contain identical ATP-sensitive K+ channels.

a)

True

b)

False

9.

Which of the following stimulates glucagon relase?

a)

Eating

b)

Fasting

c)

Exercise

d)

Sleeping

10.

Insulin facilitates glucose UPTAKE into cells via GLUT-4 transport. What type of cells account for the majority (80%) of this insulin aided uptake?

a)

muscle

b)

fat

c)

liver

d)

brain

11.

Insulin stimulates or promotes which of the following?

a)

glycogenesis

b)

fat formation in adipose tissue

c)

protein synthesis

d)

gluconeogenesis

12.

The half-life and clearance rates of insulin is measured in...

a)

minutes

b)

hours

c)

days

d)

weeks

13.

Gs-coupled GPCRs stimulate insulin release and are responsive to:

a)

glucose

b)

glucagon

c)

GLP-1

d)

GIP

14.

Gq couple GPCRs stimulate insulin release and are responsive to:

a)

muscarinic acetylcholine (mACh)

b)

cholecystokinin

c)

GLP-1

d)

somatostatin

15.

Which of the following inhibits insulin secretion?

a)

Eating

b)

Fasting

c)

Excercise

d)

Stress

16.

The number of insulin RECEPTORS is increased by:

a)

Exercise

b)

Starvation

c)

Chronically high insulin levels

d)

Obesity

17.

The number of insulin RECEPTORS is decreased by:

a)

Exercise

b)

Starvation

c)

Chronically high insulin levels

d)

Obesity