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WorksheetsAP Bio Topic 4.1-4.4
Total questions: 15
Worksheet time: 10mins
All signals and receptors are the same in all cells.
True
False
All cells have the same response to the same signal.
True
False
Adrenaline is released from your adrenal glands to affect various systems in the body. This is an example of ____ signaling.
juxtacrine (direct cell to cell contact)
endocrine (long distance)
paracrine (short distance)
autocrine (self-signaling)
Which are two widely used second messengers in many signal transduction pathways? (choose both)
cAMP
G-protein
Ca2+
adrenaline/epinephrine
What type of signaling is shown here?
autocrine (self-signaling)
juxtacrine (direct cell-to-cell contact)
endocrine (long-distance)
paracrine (short distance)
What determines whether a signal molecule binds on the surface or enters the cell?
size
polarity
ability to cross the membrane
all of these
Protein kinases can activate a protein by transferring a phosphate group to it. What is the benefit of pathways containing phosphorylation cascades with many kinases?
they increase signal reception
they create 2nd messengers
they increase amplification of the response
they terminate the signal transduction pathway
Many cancer cells signal themselves to grow and divide. This is an example of ______ signaling.
endocrine (long distance)
autocrine (self-signaling)
paracrine (short distance)
hormone (long distance)
After a cellular response is achieved, how is it terminated?
the ligand and receptor separate
block the transduction pathway
the cell will keep responding
send out a different signal
Which of the following would NOT result in the inhibition of this pathway?
A change in the shape of the receptor
The presence of a competitive ligand
Increase in hormone concentration
Loss of second messenger production
Which part of the signaling pathway could consist of protein modification, second messenger production, amplification or a phosphorylation cascade?
Reception
Transduction
Response
All of these
The B-adrenergic receptor is important because...
growth factor binds to it
It produces a secondary messenger
It is the ligand that activates the pathway
It is the target molecule that stimulates gene expression
If MNK1 remained in its active state permanently, what would be the result?
c-Myc would be unable to translate growth genes
Cell growth and division will stop
The phosphorylation cascade will stop
Cell division will increase, leading to tumor formation
Which receptor is responsible for the signaling pathway that leads to apoptosis?
Delta/Serrate/Lag-2
Frizzled
TGF-B RI/RII
Ptch
Complete the free response on the paper provided. Your score on the short answer will be doubled (score of 3= 6 points).
